Zinc aspartate suppresses T cell activation in vitro and relapsing experimental autoimmune encephalomyelitis in SJL/J mice

PETIR-001, a dual inhibitor of dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN), ameliorates experimental autoimmune encephalomyelitis in SJL/J mice

(2011) Dirk Reinhold et al.   BIOLOGICAL CHEMISTRY

Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions

(2011) Aliza Biton et al.   IMMUNOBIOLOGY

Zinc homeostasis and signaling in health and diseases

(2011) Toshiyuki Fukada et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Regulation of T cell receptor signaling by activation-induced zinc influx

(2011) Mingcan Yu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

Zinc signals promote IL-2-dependent proliferation of T cells

(2010) Jennifer Kaltenberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Zinc suppresses Th17 development via inhibition of STAT3 activation

(2010) Chika Kitabayashi et al.   INTERNATIONAL IMMUNOLOGY

TH1 and TH2 cell polarization increases with aging and is modulated by zinc supplementation

(2007) Peter Uciechowski et al.   EXPERIMENTAL GERONTOLOGY

In vitro and in vivo effects of zinc on cytokine signalling in human T cells

(2007) Audrey Varin et al.   EXPERIMENTAL GERONTOLOGY