Oral zinc aspartate treats experimental autoimmune encephalomyelitis

PTEN-inhibition by zinc ions augments interleukin-2-mediated Akt phosphorylation

(2014) Laura Marie Plum et al.   Metallomics

Multiple sclerosis: Prospects and promise

(2013) Stephen L. Hauser et al.   ANNALS OF NEUROLOGY

Using EAE to better understand principles of immune function and autoimmune pathology

(2013) Manu Rangachari et al.   JOURNAL OF AUTOIMMUNITY

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

Zinc aspartate suppresses T cell activation in vitro and relapsing experimental autoimmune encephalomyelitis in SJL/J mice

(2012) Diana Stoye et al.   BIOMETALS

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

(2011) Cris S Constantinescu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cytokines and effector T cell subsets causing autoimmune CNS disease

(2011) Franziska Petermann et al.   FEBS LETTERS

Zinc homeostasis and signaling in health and diseases

(2011) Toshiyuki Fukada et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Regulation of T cell receptor signaling by activation-induced zinc influx

(2011) Mingcan Yu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Zinc differentially regulates mitogen-activated protein kinases in human T cells

(2011) Andrea Hönscheid et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

Zinc signals promote IL-2-dependent proliferation of T cells

(2010) Jennifer Kaltenberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Free zinc ions outside a narrow concentration range are toxic to a variety of cells in vitro

(2010) Rebecca A Bozym et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Zinc suppresses Th17 development via inhibition of STAT3 activation

(2010) Chika Kitabayashi et al.   INTERNATIONAL IMMUNOLOGY

TH1 and TH2 cell polarization increases with aging and is modulated by zinc supplementation

(2007) Peter Uciechowski et al.   EXPERIMENTAL GERONTOLOGY

In vitro and in vivo effects of zinc on cytokine signalling in human T cells

(2007) Audrey Varin et al.   EXPERIMENTAL GERONTOLOGY