Large-scale interaction effects reveal missing heritability in schizophrenia, bipolar disorder and posttraumatic stress disorder

Collective Genetic Interaction Effects and the Role of Antigen-Presenting Cells in Autoimmune Diseases

(2017) Hyung Jun Woo et al.   PLoS One

Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease mechanism

(2016) Hyung Jun Woo et al.   BMC GENOMICS

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers

(2016) Murray B. Stein et al.   JAMA Psychiatry

A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces

(2015) Lynn M. Almli et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Heparan sulfation is essential for the prevention of cellular senescence

(2015) S H Jung et al.   CELL DEATH AND DIFFERENTIATION

Distinguishing schizophrenia from posttraumatic stress disorder with psychosis

(2015) Aengus OConghaile et al.   CURRENT OPINION IN PSYCHIATRY

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

(2015)   NATURE NEUROSCIENCE

The endocannabinoid system in guarding against fear, anxiety and stress

(2015) Beat Lutz et al.   NATURE REVIEWS NEUROSCIENCE

Stress and Fear Extinction

(2015) Stephen Maren et al.   NEUROPSYCHOPHARMACOLOGY

The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration

(2015) Mark W Logue et al.   NEUROPSYCHOPHARMACOLOGY

Association of age-of-onset groups with GWAS significant schizophrenia and bipolar disorder loci in Romanian bipolar I patients

(2015) Maria Grigoroiu-Serbanescu et al.   PSYCHIATRY RESEARCH

Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene

(2015) Caroline M. Nievergelt et al.   PSYCHONEUROENDOCRINOLOGY

Crosstalk between intracellular and extracellular signals regulating interneuron production, migration and integration into the cortex

(2015) Elise Peyre et al.   Frontiers in Cellular Neuroscience

Microglia Function in Central Nervous System Development and Plasticity

(2015) Dorothy P. Schafer et al.   Cold Spring Harbor Perspectives in Biology

Brain structure, cognition and negative symptoms in schizophrenia are associated with serum levels of polysialic acid-modified NCAM

(2015) F Piras et al.   Translational Psychiatry

Proteoglycans and neuronal migration in the cerebral cortex during development and disease

(2015) Nobuaki Maeda   Frontiers in Neuroscience

The Cell Biology of Neurogenesis: Toward an Understanding of the Development and Evolution of the Neocortex

(2014) Elena Taverna et al.   Annual Review of Cell and Developmental Biology

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1

(2014) Wei Xu et al.   BMC Medical Genetics

Neurogenesis during development of the vertebrate central nervous system

(2014) J. T. Paridaen et al.   EMBO REPORTS

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Peripheral gating of pain signals by endogenous lipid mediators

(2014) Daniele Piomelli et al.   NATURE NEUROSCIENCE

Maternal immune activation and abnormal brain development across CNS disorders

(2014) Irene Knuesel et al.   Nature Reviews Neurology

Polyunsaturated fatty acids and their metabolites in brain function and disease

(2014) Richard P. Bazinet et al.   NATURE REVIEWS NEUROSCIENCE

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(2014) Guy C. Brown et al.   NATURE REVIEWS NEUROSCIENCE

Neuregulin-ERBB Signaling in the Nervous System and Neuropsychiatric Diseases

(2014) Lin Mei et al.   NEURON

The CSMD1 genome-wide associated schizophrenia risk variant rs10503253 affects general cognitive ability and executive function in healthy males

(2014) Erasmia Koiliari et al.   SCHIZOPHRENIA RESEARCH

Identification of Pathways for Bipolar Disorder

(2014) John I. Nurnberger et al.   JAMA Psychiatry

Genome-wide Association Study Identifies New Susceptibility Loci for Posttraumatic Stress Disorder

(2013) Pingxing Xie et al.   BIOLOGICAL PSYCHIATRY

Genome-Wide Association Study of Opioid Dependence: Multiple Associations Mapped to Calcium and Potassium Pathways

(2013) Joel Gelernter et al.   BIOLOGICAL PSYCHIATRY

The novel complement inhibitor human CUB and Sushi multiple domains 1 (CSMD1) protein promotes factor I-mediated degradation of C4b and C3b and inhibits the membrane attack complex assembly

(2013) Astrid Escudero-Esparza et al.   FASEB JOURNAL

The Role of Secretory Phospholipase A2 in the Central Nervous System and Neurological Diseases

(2013) Tatsurou Yagami et al.   MOLECULAR NEUROBIOLOGY

Meta-analysis methods for genome-wide association studies and beyond

(2013) Evangelos Evangelou et al.   NATURE REVIEWS GENETICS

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

IgE and mast cells in allergic disease

(2012) Stephen J Galli et al.   NATURE MEDICINE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Neural and cellular mechanisms of fear and extinction memory formation

(2012) Caitlin A. Orsini et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

(2011) Michael C. Wu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia

(2011) Bjarte Håvik et al.   BIOLOGICAL PSYCHIATRY

Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets

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Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Extracellular matrix abnormalities in schizophrenia

(2011) Sabina Berretta   NEUROPHARMACOLOGY

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Chondroitin Sulfate Acts in Concert with Semaphorin 3A to Guide Tangential Migration of Cortical Interneurons in the Ventral Telencephalon

(2010) Geraldine Zimmer et al.   CEREBRAL CORTEX

Enduring consequences of maternal obesity for brain inflammation and behavior of offspring

(2010) Staci D. Bilbo et al.   FASEB JOURNAL

Alleviation of Neurotoxicity by Microglial Human Siglec-11

(2010) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

(2010) Alexander Dityatev et al.   NATURE REVIEWS NEUROSCIENCE

Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear

(2010) Hans-Christian Pape et al.   PHYSIOLOGICAL REVIEWS

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

(2010) Ayellet V. Segrè et al.   PLoS Genetics

The Genetic Interpretation of Area under the ROC Curve in Genomic Profiling

(2010) Naomi R. Wray et al.   PLoS Genetics

Leptin modulates cell morphology and cytokine release in microglia

(2009) Véronique Lafrance et al.   BRAIN BEHAVIOR AND IMMUNITY

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

(2009) Paul Lichtenstein et al.   LANCET

Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-  nuclear receptors

(2009) C. Mazzola et al.   LEARNING & MEMORY

Genome-wide association study of bipolar disorder in European American and African American individuals

(2009) E N Smith et al.   MOLECULAR PSYCHIATRY

DNA repair deficiency and neurological disease

(2009) Peter J. McKinnon   NATURE REVIEWS NEUROSCIENCE

Amygdala Inhibitory Circuits and the Control of Fear Memory

(2009) Ingrid Ehrlich et al.   NEURON

How Prevalent Are Anxiety Disorders in Schizophrenia? A Meta-Analysis and Critical Review on a Significant Association

(2009) A. M. Achim et al.   SCHIZOPHRENIA BULLETIN

Whole-genome association study of bipolar disorder

(2008) P Sklar et al.   MOLECULAR PSYCHIATRY

Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

(2008) John E. Lisman et al.   TRENDS IN NEUROSCIENCES