Meta-analysis methods for genome-wide association studies and beyond
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Meta-analysis methods for genome-wide association studies and beyond
Authors
Keywords
-
Journal
NATURE REVIEWS GENETICS
Volume 14, Issue 6, Pages 379-389
Publisher
Springer Nature
Online
2013-05-09
DOI
10.1038/nrg3472
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genome-wide association studies identify four ER negative–specific breast cancer risk loci
- (2013) Montserrat Garcia-Closas et al. NATURE GENETICS
- GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
- (2013) Paul D P Pharoah et al. NATURE GENETICS
- Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
- (2013) Rosalind A Eeles et al. NATURE GENETICS
- Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
- (2013) Stig E Bojesen et al. NATURE GENETICS
- Large-scale genotyping identifies 41 new loci associated with breast cancer risk
- (2013) Kyriaki Michailidou et al. NATURE GENETICS
- Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies
- (2012) Seunggeun Lee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Subset-Based Approach Improves Power and Interpretation for the Combined Analysis of Genetic Association Studies of Heterogeneous Traits
- (2012) Samsiddhi Bhattacharjee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- ARIEL and AMELIA: Testing for an Accumulation of Rare Variants Using Next-Generation Sequencing Data
- (2012) Jennifer L. Asimit et al. HUMAN HEREDITY
- Sex-specific differences in effect size estimates at established complex trait loci
- (2012) Gisela Orozco et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
- (2012) Benjamin F Voight et al. LANCET
- Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
- (2012) Karol Estrada et al. NATURE GENETICS
- Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
- (2012) Eli A Stahl et al. NATURE GENETICS
- Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
- (2012) Bryan Howie et al. NATURE GENETICS
- Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
- (2012) Jian Yang et al. NATURE GENETICS
- Comprehensive literature review and statistical considerations for GWAS meta-analysis
- (2012) Ferdouse Begum et al. NUCLEIC ACIDS RESEARCH
- A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans
- (2012) Nicholette D. Palmer et al. PLoS One
- Rare and Low Frequency Variant Stratification in the UK Population: Description and Impact on Association Tests
- (2012) Marie-Claude Babron et al. PLoS One
- On the covariance of two correlated log-odds ratios
- (2012) Pantelis G. Bagos STATISTICS IN MEDICINE
- Impact of Phenotype Definition on Genome-Wide Association Signals: Empirical Evaluation in Human Immunodeficiency Virus Type 1 Infection
- (2011) Evangelos Evangelou et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test
- (2011) Michael C. Wu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Estimating Missing Heritability for Disease from Genome-wide Association Studies
- (2011) Sang Hong Lee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies
- (2011) Buhm Han et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A unified framework for multi-locus association analysis of both common and rare variants
- (2011) Daniel Shriner et al. BMC GENOMICS
- The meta-analysis of genome-wide association studies
- (2011) J. R. Thompson et al. BRIEFINGS IN BIOINFORMATICS
- Mining gold dust under the genome wide significance level: a two-stage approach to analysis of GWAS
- (2011) Gang Shi et al. GENETIC EPIDEMIOLOGY
- Defining the power limits of genome-wide association scan meta-analyses
- (2011) Kay Chapman et al. GENETIC EPIDEMIOLOGY
- The use of imputed values in the meta-analysis of genome-wide association studies
- (2011) Shuo Jiao et al. GENETIC EPIDEMIOLOGY
- Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience
- (2011) Siiri N. Bennett et al. GENETIC EPIDEMIOLOGY
- Optimal methods for meta-analysis of genome-wide association studies
- (2011) Baiyu Zhou et al. GENETIC EPIDEMIOLOGY
- Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability
- (2011) Zoltán Kutalik et al. GENETIC EPIDEMIOLOGY
- Transethnic meta-analysis of genomewide association studies
- (2011) Andrew P. Morris GENETIC EPIDEMIOLOGY
- To stratify or not to stratify: power considerations for population-based genome-wide association studies of quantitative traits
- (2011) Gundula Behrens et al. GENETIC EPIDEMIOLOGY
- Consistency of genome-wide associations across major ancestral groups
- (2011) Evangelia E. Ntzani et al. HUMAN GENETICS
- Genome-Wide Meta-Analysis of Joint Tests for Genetic and Gene-Environment Interaction Effects
- (2011) Hugues Aschard et al. HUMAN HEREDITY
- What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations
- (2011) Orestis A Panagiotou et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
- (2011) Heribert Schunkert et al. NATURE GENETICS
- Pervasive Sharing of Genetic Effects in Autoimmune Disease
- (2011) Chris Cotsapas et al. PLoS Genetics
- Fine Mapping of Five Loci Associated with Low-Density Lipoprotein Cholesterol Detects Variants That Double the Explained Heritability
- (2011) Serena Sanna et al. PLoS Genetics
- Extending Rare-Variant Testing Strategies: Analysis of Noncoding Sequence and Imputed Genotypes
- (2010) Matthew Zawistowski et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Pooled Association Tests for Rare Variants in Exon-Resequencing Studies
- (2010) Alkes L. Price et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Prioritizing GWAS Results: A Review of Statistical Methods and Recommendations for Their Application
- (2010) Rita M. Cantor et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22
- (2010) E. Evangelou et al. ANNALS OF THE RHEUMATIC DISEASES
- METAL: fast and efficient meta-analysis of genomewide association scans
- (2010) C. J. Willer et al. BIOINFORMATICS
- CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
- (2010) Robert Lawrence et al. BMC BIOINFORMATICS
- GWAMA: software for genome-wide association meta-analysis
- (2010) Reedik Mägi et al. BMC BIOINFORMATICS
- The effect of next-generation sequencing technology on complex trait research
- (2010) Aaron G. Day-Williams et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Imputation aware meta-analysis of genome-wide association studies
- (2010) Noah Zaitlen et al. GENETIC EPIDEMIOLOGY
- Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients
- (2010) Alisa K. Manning et al. GENETIC EPIDEMIOLOGY
- Meta-analysis of sex-specific genome-wide association studies
- (2010) Reedik Magi et al. GENETIC EPIDEMIOLOGY
- MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
- (2010) Yun Li et al. GENETIC EPIDEMIOLOGY
- A Data-Adaptive Sum Test for Disease Association with Multiple Common or Rare Variants
- (2010) Fang Han et al. HUMAN HEREDITY
- Glad You Asked: Participants' Opinions of Re-Consent for DbGap Data Submission
- (2010) Evette J. Ludman et al. Journal of Empirical Research on Human Research Ethics
- Genome-wide meta-analyses identify multiple loci associated with smoking behavior
- (2010) NATURE GENETICS
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
- (2010) Iris M Heid et al. NATURE GENETICS
- Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation
- (2010) Geneviève Galarneau et al. NATURE GENETICS
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
- (2010) Elizabeth K Speliotes et al. NATURE GENETICS
- Variance component model to account for sample structure in genome-wide association studies
- (2010) Hyun Min Kang et al. NATURE GENETICS
- Genotype imputation for genome-wide association studies
- (2010) Jonathan Marchini et al. NATURE REVIEWS GENETICS
- Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium
- (2010) H.J.M. Kerkhof et al. OSTEOARTHRITIS AND CARTILAGE
- A New Statistic to Evaluate Imputation Reliability
- (2010) Peng Lin et al. PLoS One
- On Combining Data From Genome-Wide Association Studies to Discover Disease-Associated SNPs
- (2010) Ruth M. Pfeiffer et al. STATISTICAL SCIENCE
- A Covering Method for Detecting Genetic Associations between Rare Variants and Common Phenotypes
- (2010) Gaurav Bhatia et al. PLoS Computational Biology
- Consistent Association of Type 2 Diabetes Risk Variants Found in Europeans in Diverse Racial and Ethnic Groups
- (2010) Kevin M. Waters et al. PLoS Genetics
- Critical interpretation of Cochran's Q test depends on power and prior assumptions about heterogeneity
- (2010) Tiago V. Pereira et al. Research Synthesis Methods
- Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations
- (2009) Georgia Salanti et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Discovery Properties of Genome-wide Association Signals From Cumulatively Combined Data Sets
- (2009) T. V. Pereira et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Large-scale analysis of association betweenGDF5andFRZBvariants and osteoarthritis of the hip, knee, and hand
- (2009) Evangelos Evangelou et al. ARTHRITIS AND RHEUMATISM
- An evaluation of statistical approaches to rare variant analysis in genetic association studies
- (2009) Andrew P. Morris et al. GENETIC EPIDEMIOLOGY
- Validating, augmenting and refining genome-wide association signals
- (2009) John P. A. Ioannidis et al. NATURE REVIEWS GENETICS
- Challenges in phenotype definition in the whole-genome era: multivariate models of memory and intelligence
- (2009) F.W. Sabb et al. NEUROSCIENCE
- Meta-analysis in genome-wide association studies
- (2009) Eleftheria Zeggini et al. PHARMACOGENOMICS
- Empirical vs natural weighting in random effects meta-analysis
- (2009) Jonathan J. Shuster STATISTICS IN MEDICINE
- Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?
- (2009) Iris M. Heid et al. PLoS Genetics
- A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic
- (2009) Bo Eskerod Madsen et al. PLoS Genetics
- Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data
- (2008) Bingshan Li et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Estimation of significance thresholds for genomewide association scans
- (2008) Frank Dudbridge et al. GENETIC EPIDEMIOLOGY
- Estimation of the multiple testing burden for genomewide association studies of nearly all common variants
- (2008) Itsik Pe'er et al. GENETIC EPIDEMIOLOGY
- Bayes factors for genome-wide association studies: comparison withP-values
- (2008) Jon Wakefield GENETIC EPIDEMIOLOGY
- Practical aspects of imputation-driven meta-analysis of genome-wide association studies
- (2008) P. I.W. de Bakker et al. HUMAN MOLECULAR GENETICS
- Genome-wide association studies for complex traits: consensus, uncertainty and challenges
- (2008) Mark I. McCarthy et al. NATURE REVIEWS GENETICS
- Genotype-Phenotype Associations in Obesity Dependent on Definition of the Obesity Phenotype
- (2008) Sofia Inez Iqbal Kring et al. Obesity Facts
- Analysis and Application of European Genetic Substructure Using 300 K SNP Information
- (2008) Chao Tian et al. PLoS Genetics
- Required sample size and nonreplicability thresholds for heterogeneous genetic associations
- (2008) R. Moonesinghe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Unification of Multivariate Methods for Meta-Analysis of Genetic Association Studies
- (2008) Pantelis G Bagos Statistical Applications in Genetics and Molecular Biology
- Why add anything to nothing? The arcsine difference as a measure of treatment effect in meta-analysis with zero cells
- (2008) Gerta Rücker et al. STATISTICS IN MEDICINE
- Tracing Sub-Structure in the European American Population with PCA-Informative Markers
- (2008) Peristera Paschou et al. PLoS Genetics
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now