Separate roles for chromatin and lamins in nuclear mechanics

Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins

(2018) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanosensing by the nucleus: From pathways to scaling relationships

(2017) Sangkyun Cho et al.   JOURNAL OF CELL BIOLOGY

Nucleosome–nucleosome interactions via histone tails and linker DNA regulate nuclear rigidity

(2017) Yuta Shimamoto et al.   MOLECULAR BIOLOGY OF THE CELL

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

(2017) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

Phase separation drives heterochromatin domain formation

(2017) Amy R. Strom et al.   NATURE

The molecular architecture of lamins in somatic cells

(2017) Yagmur Turgay et al.   NATURE

The 4D nucleome project

(2017) Job Dekker et al.   NATURE

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

(2017) Adam G. Larson et al.   NATURE

Atomic Force Microscopy micro-rheology reveals large structural inhomogeneities in single cell-nuclei

(2017) Michael Lherbette et al.   Scientific Reports

The 3D Genome as Moderator of Chromosomal Communication

(2016) Job Dekker et al.   CELL

Transcription upregulation via force-induced direct stretching of chromatin

(2016) Arash Tajik et al.   NATURE MATERIALS

Visualizing the molecular sociology at the HeLa cell nuclear periphery

(2016) J. Mahamid et al.   SCIENCE

Extracellular Forces Cause the Nucleus to Deform in a Highly Controlled Anisotropic Manner

(2016) Kristina Haase et al.   Scientific Reports

Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins

(2015) Jennifer C. Harr et al.   JOURNAL OF CELL BIOLOGY

Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell

(2015) Srujana Neelam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness

(2015) Takashi Furusawa et al.   Nature Communications

The tethering of chromatin to the nuclear envelope supports nuclear mechanics

(2015) Sarah M. Schreiner et al.   Nature Communications

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus

(2014) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Auxetic nuclei in embryonic stem cells exiting pluripotency

(2014) Stefano Pagliara et al.   NATURE MATERIALS

Mapping of protein- and chromatin-interactions at the nuclear lamina

(2014) Nard Kubben et al.   Nucleus

Nuclear Mechanics and Mechanotransduction in Health and Disease

(2013) Philipp Isermann et al.   CURRENT BIOLOGY

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Probing the compressibility of tumor cell nuclei by combined atomic force–confocal microscopy

(2013) Marina Krause et al.   PHYSICAL BIOLOGY

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Nuclear lamin functions and disease

(2012) Veronika Butin-Israeli et al.   TRENDS IN GENETICS

Nuclear mechanics during cell migration

(2010) Peter Friedl et al.   CURRENT OPINION IN CELL BIOLOGY

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

Influence of Lamin A on the Mechanical Properties of Amphibian Oocyte Nuclei Measured by Atomic Force Microscopy

(2009) Jens Schäpe et al.   BIOPHYSICAL JOURNAL