Treatment of Diabetes Mellitus Using iPS Cells and Spice Polyphenols

ω-3 polyunsaturated fatty acids ameliorate type 1 diabetes and autoimmunity

(2017) Xinyun Bi et al.   JOURNAL OF CLINICAL INVESTIGATION

Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance

(2016) Pingping Li et al.   CELL

UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness

(2016) Chitoku Toda et al.   CELL

Metformin reduces the rate of small intestinal glucose absorption in type 2 diabetes

(2016) Tongzhi Wu et al.   DIABETES OBESITY & METABOLISM

Remission of congenital hyperinsulinism following conservative treatment: an exploratory study in patients with KATP channel mutations

(2016) Mark J. Lachmann et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Curcumin activates autophagy and attenuates oxidative damage in EA.hy926 cells via the Akt/mTOR pathway

(2016) SHOUYU GUO et al.   Molecular Medicine Reports

Fatty acid synthesis configures the plasma membrane for inflammation in diabetes

(2016) Xiaochao Wei et al.   NATURE

Identification of proliferative and mature β-cells in the islets of Langerhans

(2016) Erik Bader et al.   NATURE

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

(2016) James Dooley et al.   NATURE GENETICS

Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents

(2016) Jarrad M Scarlett et al.   NATURE MEDICINE

A formulation of grape seed, Indian gooseberry, turmeric and fenugreek helps controlling type 2 diabetes mellitus in advanced-stage patients

(2016) Sangeeta Banerji et al.   European Journal of Integrative Medicine

Generation of functional hepatocytes from human spermatogonial stem cells

(2016) Zheng Chen et al.   Oncotarget

Curcumin Suppresses Proliferation and Migration of MDA-MB-231 Breast Cancer Cells through Autophagy-Dependent Akt Degradation

(2016) Feng Guan et al.   PLoS One

Neuroprotective effects of (Val8)GLP-1-Glu-PAL in the MPTP Parkinson’s disease mouse model

(2015) YanFang Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Long Noncoding RNA MALAT-1 Enhances Stem Cell-Like Phenotypes in Pancreatic Cancer Cells

(2015) Feng Jiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

The effect of ginger powder supplementation on insulin resistance and glycemic indices in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trial

(2014) Hassan Mozaffari-Khosravi et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Decrease of postprandial endothelial dysfunction by spice mix added to high-fat hamburger meat in men with Type 2 diabetes mellitus

(2013) Z. Li et al.   DIABETIC MEDICINE

Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes

(2012) Ting Lu et al.   NUTRITION RESEARCH

Gingerols of Zingiber officinale Enhance Glucose Uptake by Increasing Cell Surface GLUT4 in Cultured L6 Myotubes

(2012) Yiming Li et al.   PLANTA MEDICA

Primary and Secondary Prevention Strategy for Cardiovascular Disease in Diabetes Mellitus

(2011) Sundararajan Srikanth et al.   CARDIOLOGY CLINICS

iPS Cells in Type 1 Diabetes Research and Treatment

(2011) R Maehr   CLINICAL PHARMACOLOGY & THERAPEUTICS

Stem cell-based treatments for Type 1 diabetes mellitus: bone marrow, embryonic, hepatic, pancreatic and induced pluripotent stem cells

(2011) K. J. Godfrey et al.   DIABETIC MEDICINE

Immune intervention in type 1 diabetes

(2011) Aaron W. Michels et al.   SEMINARS IN IMMUNOLOGY

Enrichment of Human ESC-Derived Multipotent Mesenchymal Stem Cells with Immunosuppressive and Anti-Inflammatory Properties Capable to Protect Against Experimental Inflammatory Bowel Disease

(2010) Laura Sánchez et al.   STEM CELLS

Prediction and prevention of Type 1 diabetes mellitus

(2010) Li ZHANG et al.   Journal of Diabetes

Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells

(2009) Donghui Zhang et al.   CELL RESEARCH

Are stem cells a cure for diabetes?

(2009) Michael D. McCall et al.   CLINICAL SCIENCE

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Effectiveness of Cinnamon for Lowering Hemoglobin A1C in Patients with Type 2 Diabetes: A Randomized, Controlled Trial

(2009) P. Crawford   Journal of the American Board of Family Medicine

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Hypoglycemic activity of a polyphenolic oligomer-rich extract of Cinnamomum parthenoxylon bark in normal and streptozotocin-induced diabetic rats

(2009) Q. Jia et al.   PHYTOMEDICINE

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Generation of Insulin-secreting Islet-like Clusters from Human Skin Fibroblasts

(2008) Keisuke Tateishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microfluidic device for multimodal characterization of pancreatic islets

(2008) Javeed Shaikh Mohammed et al.   LAB ON A CHIP

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bioinformatics analysis of functional protein sequences reveals a role for brain-derived neurotrophic factor in obesity and type 2 diabetes mellitus

(2007) Allam Appa Rao et al.   MEDICAL HYPOTHESES