Prediction and prevention of Type 1 diabetes mellitus

Banting Lecture 2009: An Unfinished Journey: Molecular Pathogenesis to Prevention of Type 1A Diabetes

(2010) G. S. Eisenbarth   DIABETES

Entities and frequency of neonatal diabetes: data from the diabetes documentation and quality management system (DPV)

(2010) J. Grulich-Henn et al.   DIABETIC MEDICINE

Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies

(2010) M. Schlosser et al.   DIABETOLOGIA

Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass

(2010) B. Keymeulen et al.   DIABETOLOGIA

Humoral Autoimmunity against the Extracellular Domain of the Neuroendocrine Autoantigen IA-2 Heightens the Risk of Type 1 Diabetes

(2010) Michael P. Morran et al.   ENDOCRINOLOGY

Combination therapies for Type 1 diabetes: why not now?

(2010) Matthias von Herrath   Immunotherapy

Immunotherapy of type 1 diabetes — How to rationally prioritize combination therapies in T1D

(2010) Tobias Boettler et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Harmonization of Glutamic Acid Decarboxylase and Islet Antigen-2 Autoantibody Assays for National Institute of Diabetes and Digestive and Kidney Diseases Consortia

(2010) Ezio Bonifacio et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ofatumumab

(2010) Bodi Zhang   mAbs

Anti-CD20 Treatment Prolongs Syngeneic Islet Graft Survival and Delays the Onset of Recurrent Autoimmune Diabetes

(2009) Changyun Hu et al.   Annals of the New York Academy of Sciences

SlC30A8 Is a Major Target of Humoral Autoimmunity in Type 1 Diabetes and a Predictive Marker in Prediabetes

(2009) Janet M. Wenzlau et al.   Annals of the New York Academy of Sciences

Autoimmune Type 1 Diabetes Genetic Susceptibility Encoded by Human Leukocyte Antigen DRB1 and DQB1 Genes in Tunisia

(2009) M. Stayoussef et al.   Clinical and Vaccine Immunology

A new automated human leukocyte antigen genotyping strategy to identify DR-DQ risk alleles for celiac disease and type 1 diabetes mellitus

(2009) Ewa H. Lavant et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years

(2009) Kevan C. Herold et al.   CLINICAL IMMUNOLOGY

Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodies

(2009) Simona Cernea et al.   CLINICAL IMMUNOLOGY

Diabetic Subjects Diagnosed Through the Diabetes Prevention Trial-Type 1 (DPT-1) Are Often Asymptomatic With Normal A1C at Diabetes Onset

(2009) T. M. Triolo et al.   DIABETES CARE

Pancreatic Islet Autoantibodies as Predictors of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1

(2009) T. Orban et al.   DIABETES CARE

The incidence of type 1 diabetes is increasing in both children and young adults in Northern Italy: 1984–2004 temporal trends

(2009) G. Bruno et al.   DIABETOLOGIA

Predictive power of screening for antibodies against insulinoma-associated protein 2 beta (IA-2β) and zinc transporter-8 to select first-degree relatives of type 1 diabetic patients with risk of rapid progression to clinical onset of the disease: implications for prevention trials

(2009) J. De Grijse et al.   DIABETOLOGIA

Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk

(2009) P. Achenbach et al.   DIABETOLOGIA

Clinical Applications of Diabetes Antibody Testing

(2009) Polly J. Bingley   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetics of Type 1A Diabetes

(2009) Patrick Concannon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species

(2008) Dan B. Rainbow et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Modulating the natural history of type 1 diabetes in children at high genetic risk by mucosal insulin immunization

(2008) Peter Achenbach et al.   Current Diabetes Reports

Two Single Nucleotide Polymorphisms Identify the Highest-Risk Diabetes HLA Genotype: Potential for Rapid Screening

(2008) J. M. Barker et al.   DIABETES

Autoantibodies to IA-2β improve diabetes risk assessment in high-risk relatives

(2008) P. Achenbach et al.   DIABETOLOGIA

Characterization of the humoral immune response to islet antigen 2 in children with newly diagnosed type 1 diabetes.

(2008) Anna Mäkinen et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Concordance for Islet Autoimmunity among Monozygotic Twins

(2008) Maria J. Redondo et al.   NEW ENGLAND JOURNAL OF MEDICINE

GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes

(2008) Johnny Ludvigsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enhanced levels of cow’s milk antibodies in infancy in children who develop type 1 diabetes later in childhood

(2008) Kristiina Luopajärvi et al.   PEDIATRIC DIABETES

The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results

(2008) Jeffrey L Mahon et al.   PEDIATRIC DIABETES