Structure-Based Prototype Peptides Targeting the Pseudomonas aeruginosa Type VI Secretion System Effector as a Novel Antibacterial Strategy

Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides

(2017) Sung-Min Kang et al.   NUCLEIC ACIDS RESEARCH

Aim, Load, Fire: The Type VI Secretion System, a Bacterial Nanoweapon

(2016) Francesca R. Cianfanelli et al.   TRENDS IN MICROBIOLOGY

The Pseudomonas aeruginosa Type VI Secretion PGAP1-like Effector Induces Host Autophagy by Activating Endoplasmic Reticulum Stress

(2016) Feng Jiang et al.   Cell Reports

Structure, Biology, and Therapeutic Application of Toxin–Antitoxin Systems in Pathogenic Bacteria

(2016) Ki-Young Lee et al.   Toxins

The T6SSs of Pseudomonas aeruginosa Strain PAO1 and Their Effectors: Beyond Bacterial-Cell Targeting

(2016) Thibault G. Sana et al.   Frontiers in Cellular and Infection Microbiology

An Interbacterial NAD(P)+ Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells

(2015) John C. Whitney et al.   CELL

Molecular weaponry: diverse effectors delivered by the Type VI secretion system

(2015) Juliana Alcoforado Diniz et al.   CELLULAR MICROBIOLOGY

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

The increasing threat of Pseudomonas aeruginosa high-risk clones

(2015) Antonio Oliver et al.   DRUG RESISTANCE UPDATES

Structural and functional studies of theMycobacterium tuberculosisVapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides

(2015) In-Gyun Lee et al.   NUCLEIC ACIDS RESEARCH

Genetically distinct pathways guide effector export through the type VI secretion system

(2014) John C. Whitney et al.   MOLECULAR MICROBIOLOGY

US vows to combat antibiotic resistance

(2014) Sara Reardon   NATURE

Type VI secretion system effectors: poisons with a purpose

(2014) Alistair B. Russell et al.   NATURE REVIEWS MICROBIOLOGY

VgrG, Tae, Tle, and beyond: the versatile arsenal of Type VI secretion effectors

(2014) Eric Durand et al.   TRENDS IN MICROBIOLOGY

The structural basis of the Tle4–Tli4 complex reveals the self-protection mechanism of H2-T6SS inPseudomonas aeruginosa

(2014) Defen Lu et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3

(2013) Cheng Dong et al.   BIOCHEMICAL JOURNAL

Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates

(2013) Julie M. Silverman et al.   MOLECULAR CELL

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors

(2013) Alistair B. Russell et al.   NATURE

PAAR-repeat proteins sharpen and diversify the type VI secretion system spike

(2013) Mikhail M. Shneider et al.   NATURE

PDBsum additions

(2013) Tjaart A. P. de Beer et al.   NUCLEIC ACIDS RESEARCH

A Widespread Bacterial Type VI Secretion Effector Superfamily Identified Using a Heuristic Approach

(2012) Alistair B. Russell et al.   Cell Host & Microbe

Design and synthesis of peptides from bacterial ParE toxin as inhibitors of topoisomerases

(2012) Luiz Carlos Bertucci Barbosa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structural Basis of Potent and Broad HIV-1 Fusion Inhibitor CP32M

(2012) Xue Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Escherichia coli Extracellular Death Factor EDF Induces the Endoribonucleolytic Activities of the Toxins MazF and ChpBK

(2011) Maria Belitsky et al.   MOLECULAR CELL

Type VI secretion delivers bacteriolytic effectors to target cells

(2011) Alistair B. Russell et al.   NATURE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PemK Toxin ofBacillus anthracisIs a Ribonuclease

(2009) Shivangi Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY