Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
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Title
Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
Authors
Keywords
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Journal
eLife
Volume 6, Issue -, Pages -
Publisher
eLife Sciences Organisation, Ltd.
Online
2017-04-18
DOI
10.7554/elife.20725
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Note: Only part of the references are listed.- Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling
- (2016) David J. Simon et al. CELL
- Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules
- (2016) L. Yang et al. JOURNAL OF NEUROSCIENCE
- Axonal Degeneration Is Regulated by a Transcriptional Program that Coordinates Expression of Pro- and Anti-degenerative Factors
- (2016) Maya Maor-Nof et al. NEURON
- Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses
- (2016) Karpagam Srinivasan et al. Nature Communications
- Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury
- (2016) Maritza Oñate et al. Scientific Reports
- Single-cell RNA-seq reveals distinct injury responses in different types of DRG sensory neurons
- (2016) Ganlu Hu et al. Scientific Reports
- The Unfolded Protein Response and Cholesterol Biosynthesis Link Luman/CREB3 to Regenerative Axon Growth in Sensory Neurons
- (2015) Z. Ying et al. JOURNAL OF NEUROSCIENCE
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity
- (2015) M Halliday et al. Cell Death & Disease
- The transcriptional landscape of dorsal root ganglia after sciatic nerve transection
- (2015) Shiying Li et al. Scientific Reports
- Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response
- (2015) Carmela Sidrauski et al. eLife
- Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions
- (2014) Jimena Baleriola et al. CELL
- CHAC1/MGC4504 Is a Novel Proapoptotic Component of the Unfolded Protein Response, Downstream of the ATF4-ATF3-CHOP Cascade
- (2014) I. N. Mungrue et al. JOURNAL OF IMMUNOLOGY
- Discovery of Dual Leucine Zipper Kinase (DLK, MAP3K12) Inhibitors with Activity in Neurodegeneration Models
- (2014) Snahel Patel et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nuclear and cytosolic JNK signalling in neurons
- (2014) Eleanor T. Coffey NATURE REVIEWS NEUROSCIENCE
- RNA Sequence Reveals Mouse Retinal Transcriptome Changes Early after Axonal Injury
- (2014) Masayuki Yasuda et al. PLoS One
- Production and Isolation of Axons from Sensory Neurons for Biochemical Analysis Using Porous Filters
- (2014) Nicolas Unsain et al. Jove-Journal of Visualized Experiments
- The DLK signalling pathway—a double-edged sword in neural development and regeneration
- (2013) Andrea Tedeschi et al. EMBO REPORTS
- JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells
- (2013) Kimberly A. Fernandes et al. EXPERIMENTAL EYE RESEARCH
- JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis
- (2013) Sarah Huntwork-Rodriguez et al. JOURNAL OF CELL BIOLOGY
- Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
- (2013) Tao Ma et al. NATURE NEUROSCIENCE
- Regulation of Axon Degeneration after Injury and in Development by the Endogenous Calpain Inhibitor Calpastatin
- (2013) Jing Yang et al. NEURON
- Targeting the unfolded protein response in neurodegeneration: A new approach to therapy
- (2013) Mark Halliday et al. NEUROPHARMACOLOGY
- Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis
- (2013) Soledad Matus et al. PLoS One
- Automatic Nuclei Segmentation in H&E Stained Breast Cancer Histopathology Images
- (2013) Mitko Veta et al. PLoS One
- DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury
- (2013) T. A. Watkins et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death
- (2013) D. S. Welsbie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A New PERKspective on Neurodegeneration
- (2013) W. Scheper et al. Science Translational Medicine
- Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
- (2013) J. A. Moreno et al. Science Translational Medicine
- Pharmacological brake-release of mRNA translation enhances cognitive memory
- (2013) Carmela Sidrauski et al. eLife
- Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)
- (2012) Jeffrey M. Axten et al. JOURNAL OF MEDICINAL CHEMISTRY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death
- (2012) Kimberly A. Fernandes et al. NEUROBIOLOGY OF DISEASE
- Differential Effects of Unfolded Protein Response Pathways on Axon Injury-Induced Death of Retinal Ganglion Cells
- (2012) Yang Hu et al. NEURON
- Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration
- (2012) Jung Eun Shin et al. NEURON
- Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to EnhanceCHOPTranslation
- (2011) Lakshmi Reddy Palam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity
- (2011) Arundhati Sengupta Ghosh et al. JOURNAL OF CELL BIOLOGY
- The Unfolded Protein Response Is a Major Mechanism by Which LRP1 Regulates Schwann Cell Survival after Injury
- (2011) E. Mantuano et al. JOURNAL OF NEUROSCIENCE
- Gadd45a protects against cell death in dorsal root ganglion neurons following peripheral nerve injury
- (2011) Chung-Ren Lin et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Fast and SNP-tolerant detection of complex variants and splicing in short reads
- (2010) T. D. Wu et al. BIOINFORMATICS
- PKR-like endoplasmic reticulum kinase (PERK) activation following brain ischemia is independent of unfolded nascent proteins
- (2010) T.H. Sanderson et al. NEUROSCIENCE
- The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts
- (2009) Tatsuya Yoshizawa et al. JOURNAL OF CLINICAL INVESTIGATION
- Axotomy-Induced Smad1 Activation Promotes Axonal Growth in Adult Sensory Neurons
- (2009) H. Zou et al. JOURNAL OF NEUROSCIENCE
- APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
- (2009) Anatoly Nikolaev et al. NATURE
- Conditioning lesions enhance growth state only in sensory neurons lacking calcitonin gene-related peptide and isolectin B4-binding
- (2009) A. Kalous et al. NEUROSCIENCE
- ATF4-Mediated Induction of 4E-BP1 Contributes to Pancreatic β Cell Survival under Endoplasmic Reticulum Stress
- (2008) Suguru Yamaguchi et al. Cell Metabolism
- ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo
- (2008) Philipp S. Lange et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Species and strain differences in rodent sciatic nerve anatomy: Implications for studies of neuropathic pain
- (2008) Marcel Rigaud et al. PAIN
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