Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
出版年份 2017 全文链接
标题
Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
作者
关键词
-
出版物
eLife
Volume 6, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2017-04-18
DOI
10.7554/elife.20725
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling
- (2016) David J. Simon et al. CELL
- Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules
- (2016) L. Yang et al. JOURNAL OF NEUROSCIENCE
- Axonal Degeneration Is Regulated by a Transcriptional Program that Coordinates Expression of Pro- and Anti-degenerative Factors
- (2016) Maya Maor-Nof et al. NEURON
- Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses
- (2016) Karpagam Srinivasan et al. Nature Communications
- Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury
- (2016) Maritza Oñate et al. Scientific Reports
- Single-cell RNA-seq reveals distinct injury responses in different types of DRG sensory neurons
- (2016) Ganlu Hu et al. Scientific Reports
- The Unfolded Protein Response and Cholesterol Biosynthesis Link Luman/CREB3 to Regenerative Axon Growth in Sensory Neurons
- (2015) Z. Ying et al. JOURNAL OF NEUROSCIENCE
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity
- (2015) M Halliday et al. Cell Death & Disease
- The transcriptional landscape of dorsal root ganglia after sciatic nerve transection
- (2015) Shiying Li et al. Scientific Reports
- Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response
- (2015) Carmela Sidrauski et al. eLife
- Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions
- (2014) Jimena Baleriola et al. CELL
- CHAC1/MGC4504 Is a Novel Proapoptotic Component of the Unfolded Protein Response, Downstream of the ATF4-ATF3-CHOP Cascade
- (2014) I. N. Mungrue et al. JOURNAL OF IMMUNOLOGY
- Discovery of Dual Leucine Zipper Kinase (DLK, MAP3K12) Inhibitors with Activity in Neurodegeneration Models
- (2014) Snahel Patel et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nuclear and cytosolic JNK signalling in neurons
- (2014) Eleanor T. Coffey NATURE REVIEWS NEUROSCIENCE
- RNA Sequence Reveals Mouse Retinal Transcriptome Changes Early after Axonal Injury
- (2014) Masayuki Yasuda et al. PLoS One
- Production and Isolation of Axons from Sensory Neurons for Biochemical Analysis Using Porous Filters
- (2014) Nicolas Unsain et al. Jove-Journal of Visualized Experiments
- The DLK signalling pathway—a double-edged sword in neural development and regeneration
- (2013) Andrea Tedeschi et al. EMBO REPORTS
- JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells
- (2013) Kimberly A. Fernandes et al. EXPERIMENTAL EYE RESEARCH
- JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis
- (2013) Sarah Huntwork-Rodriguez et al. JOURNAL OF CELL BIOLOGY
- Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
- (2013) Tao Ma et al. NATURE NEUROSCIENCE
- Regulation of Axon Degeneration after Injury and in Development by the Endogenous Calpain Inhibitor Calpastatin
- (2013) Jing Yang et al. NEURON
- Targeting the unfolded protein response in neurodegeneration: A new approach to therapy
- (2013) Mark Halliday et al. NEUROPHARMACOLOGY
- Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis
- (2013) Soledad Matus et al. PLoS One
- Automatic Nuclei Segmentation in H&E Stained Breast Cancer Histopathology Images
- (2013) Mitko Veta et al. PLoS One
- DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury
- (2013) T. A. Watkins et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death
- (2013) D. S. Welsbie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A New PERKspective on Neurodegeneration
- (2013) W. Scheper et al. Science Translational Medicine
- Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
- (2013) J. A. Moreno et al. Science Translational Medicine
- Pharmacological brake-release of mRNA translation enhances cognitive memory
- (2013) Carmela Sidrauski et al. eLife
- Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)
- (2012) Jeffrey M. Axten et al. JOURNAL OF MEDICINAL CHEMISTRY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death
- (2012) Kimberly A. Fernandes et al. NEUROBIOLOGY OF DISEASE
- Differential Effects of Unfolded Protein Response Pathways on Axon Injury-Induced Death of Retinal Ganglion Cells
- (2012) Yang Hu et al. NEURON
- Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration
- (2012) Jung Eun Shin et al. NEURON
- Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to EnhanceCHOPTranslation
- (2011) Lakshmi Reddy Palam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity
- (2011) Arundhati Sengupta Ghosh et al. JOURNAL OF CELL BIOLOGY
- The Unfolded Protein Response Is a Major Mechanism by Which LRP1 Regulates Schwann Cell Survival after Injury
- (2011) E. Mantuano et al. JOURNAL OF NEUROSCIENCE
- Gadd45a protects against cell death in dorsal root ganglion neurons following peripheral nerve injury
- (2011) Chung-Ren Lin et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Fast and SNP-tolerant detection of complex variants and splicing in short reads
- (2010) T. D. Wu et al. BIOINFORMATICS
- PKR-like endoplasmic reticulum kinase (PERK) activation following brain ischemia is independent of unfolded nascent proteins
- (2010) T.H. Sanderson et al. NEUROSCIENCE
- The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts
- (2009) Tatsuya Yoshizawa et al. JOURNAL OF CLINICAL INVESTIGATION
- Axotomy-Induced Smad1 Activation Promotes Axonal Growth in Adult Sensory Neurons
- (2009) H. Zou et al. JOURNAL OF NEUROSCIENCE
- APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
- (2009) Anatoly Nikolaev et al. NATURE
- Conditioning lesions enhance growth state only in sensory neurons lacking calcitonin gene-related peptide and isolectin B4-binding
- (2009) A. Kalous et al. NEUROSCIENCE
- ATF4-Mediated Induction of 4E-BP1 Contributes to Pancreatic β Cell Survival under Endoplasmic Reticulum Stress
- (2008) Suguru Yamaguchi et al. Cell Metabolism
- ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo
- (2008) Philipp S. Lange et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Species and strain differences in rodent sciatic nerve anatomy: Implications for studies of neuropathic pain
- (2008) Marcel Rigaud et al. PAIN
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now