JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis

DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury

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Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death

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The Phr1 Ubiquitin Ligase Promotes Injury-Induced Axon Self-Destruction

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JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death

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Regulation of DLK-1 Kinase Activity by Calcium-Mediated Dissociation from an Inhibitory Isoform

(2012) Dong Yan et al.   NEURON

Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration

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The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

(2012) Xin Xiong et al.   PLOS BIOLOGY

DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity

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Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury

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Improved Quantitative Mass Spectrometry Methods for Characterizing Complex Ubiquitin Signals

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Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

(2009) Martin Schwickart et al.   NATURE

A dual leucine kinase–dependent axon self-destruction program promotes Wallerian degeneration

(2009) Bradley R Miller et al.   NATURE NEUROSCIENCE

Axon Regeneration Requires a Conserved MAP Kinase Pathway

(2009) M. Hammarlund et al.   SCIENCE

Antiapoptotic and Trophic Effects of Dominant-Negative Forms of Dual Leucine Zipper Kinase in Dopamine Neurons of the Substantia Nigra In Vivo

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The Impact of Peptide Abundance and Dynamic Range on Stable-Isotope-Based Quantitative Proteomic Analyses

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