Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody

Generation of monoclonal antibodies against native viral proteins using antigen-expressing mammalian cells for mouse immunization

(2016) Natalie Rose et al.   BMC BIOTECHNOLOGY

Essential Role of the PfRh5/PfRipr/CyRPA Complex during Plasmodium falciparum Invasion of Erythrocytes

(2016) Jennifer C. Volz et al.   Cell Host & Microbe

Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA

(2016) Paola Favuzza et al.   MALARIA JOURNAL

Protein Crystallography in Vaccine Research and Development

(2015) Enrico Malito et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial forPlasmodium falciparumerythrocyte invasion

(2015) K. Sony Reddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Analysis of Bacterial ABC Transporter Inhibition by an Antibody Fragment

(2015) Shivani Ahuja et al.   STRUCTURE

Paths to a malaria vaccine illuminated by parasite genomics

(2015) David J. Conway   TRENDS IN GENETICS

The case for a rational genome-based vaccine against malaria

(2015) Carla Proietti et al.   Frontiers in Microbiology

Malaria vaccines: identifying Plasmodium falciparum liver-stage targets

(2015) Rhea J. Longley et al.   Frontiers in Microbiology

Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens

(2015) Lassi Liljeroos et al.   Journal of Immunology Research

Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies

(2014) Katherine E. Wright et al.   NATURE

Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts

(2014) Thomas D. Otto et al.   Nature Communications

Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes

(2014) Lin Chen et al.   eLife

Antibody and B cell responses to Plasmodium sporozoites

(2014) Johanna N. Dups et al.   Frontiers in Microbiology

Reverse vaccinology in the 21st century: improvements over the original design

(2013) Claudio Donati et al.   Annals of the New York Academy of Sciences

riDOM, a cell penetrating peptide. Interaction with phospholipid bilayers

(2013) Gabriela Québatte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural Vaccinology: A Three-dimensional View for Vaccine Development

(2013) Ilaria Ferlenghi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Neutralization of Plasmodium falciparum Merozoites by Antibodies against PfRH5

(2013) A. D. Douglas et al.   JOURNAL OF IMMUNOLOGY

Max Bergmann lecture Protein epitope mimetics in the age of structural vaccinology

(2013) John A. Robinson   JOURNAL OF PEPTIDE SCIENCE

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

(2013) Enrico Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host sialoglycans and bacterial sialidases: a mucosal perspective

(2012) Amanda L. Lewis et al.   CELLULAR MICROBIOLOGY

Development of a virosomal malaria vaccine candidate: from synthetic peptide design to clinical concept validation

(2012) Gerd Pluschke et al.   Future Virology

The cellular and molecular basis for malaria parasite invasion of the human red blood cell

(2012) Alan F. Cowman et al.   JOURNAL OF CELL BIOLOGY

Passive Immunoprotection of Plasmodium falciparum-Infected Mice Designates the CyRPA as Candidate Malaria Vaccine Antigen

(2012) A. M. Dreyer et al.   JOURNAL OF IMMUNOLOGY

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

(2012) Magnus Manske et al.   NATURE

Structural vaccinology starts to deliver

(2012) Philip R. Dormitzer et al.   NATURE REVIEWS MICROBIOLOGY

A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants

(2012) Leyla Y. Bustamante et al.   VACCINE

An efficient system to generate monoclonal antibodies against membrane-associated proteins by immunisation with antigen-expressing mammalian cells

(2011) Anita M Dreyer et al.   BMC BIOTECHNOLOGY

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum

(2011) Cécile Crosnier et al.   NATURE

Virosome-Formulated Plasmodium falciparum AMA-1 & CSP Derived Peptides as Malaria Vaccine: Randomized Phase 1b Trial in Semi-Immune Adults & Children

(2011) Patrick Georges Cech et al.   PLoS One

The many blades of the β-propeller proteins: conserved but versatile

(2011) Cammy K.-M. Chen et al.   TRENDS IN BIOCHEMICAL SCIENCES

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

(2011) Alexander D. Douglas et al.   Nature Communications

An EGF-like Protein Forms a Complex with PfRh5 and Is Required for Invasion of Human Erythrocytes by Plasmodium falciparum

(2011) Lin Chen et al.   PLoS Pathogens

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Improved Murine Model of Malaria Using Plasmodium falciparum Competent Strains and Non-Myelodepleted NOD-scid IL2R null Mice Engrafted with Human Erythrocytes

(2009) M. B. Jimenez-Diaz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetics of antigenic variation in Plasmodium falciparum

(2009) Ron Dzikowski et al.   CURRENT GENETICS

Extreme Polymorphism in a Vaccine Antigen and Risk of Clinical Malaria: Implications for Vaccine Development

(2009) S. L. Takala et al.   Science Translational Medicine

Structural insights into sialic acid enzymology

(2008) Alejandro Buschiazzo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Reticulocyte-binding protein homologue 5 – An essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum

(2008) Jake Baum et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Structure-based antigen design: a strategy for next generation vaccines

(2008) Philip R. Dormitzer et al.   TRENDS IN BIOTECHNOLOGY