Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial forPlasmodium falciparumerythrocyte invasion

Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria

(2014) P. Srinivasan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterially Expressed Full-Length Recombinant Plasmodium falciparum RH5 Protein Binds Erythrocytes and Elicits Potent Strain-Transcending Parasite-Neutralizing Antibodies

(2013) K. Sony Reddy et al.   INFECTION AND IMMUNITY

Neutralization of Plasmodium falciparum Merozoites by Antibodies against PfRH5

(2013) A. D. Douglas et al.   JOURNAL OF IMMUNOLOGY

Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to Plasmodium falciparum Malaria for Vaccine and Biomarker Development

(2013) J. S. Richards et al.   JOURNAL OF IMMUNOLOGY

Various PfRH5 polymorphisms can support Plasmodium falciparum invasion into the erythrocytes of owl monkeys and rats

(2013) Karen Hayton et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Effective Identification of Akt Interacting Proteins by Two-Step Chemical Crosslinking, Co-Immunoprecipitation and Mass Spectrometry

(2013) Bill X. Huang et al.   PLoS One

RH5-Basigin interaction plays a major role in the host tropism of Plasmodium falciparum

(2013) M. Wanaguru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disrupting malaria parasite AMA1–RON2 interaction with a small molecule prevents erythrocyte invasion

(2013) Prakash Srinivasan et al.   Nature Communications

Identification of a Potent Combination of Key Plasmodium falciparum Merozoite Antigens That Elicit Strain-Transcending Parasite-Neutralizing Antibodies

(2012) Alok K. Pandey et al.   INFECTION AND IMMUNITY

The cellular and molecular basis for malaria parasite invasion of the human red blood cell

(2012) Alan F. Cowman et al.   JOURNAL OF CELL BIOLOGY

Passive Immunoprotection of Plasmodium falciparum-Infected Mice Designates the CyRPA as Candidate Malaria Vaccine Antigen

(2012) A. M. Dreyer et al.   JOURNAL OF IMMUNOLOGY

Protein–protein interaction inhibitors get into the groove

(2012) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants

(2012) Leyla Y. Bustamante et al.   VACCINE

Enhancing Blockade of Plasmodium falciparum Erythrocyte Invasion: Assessing Combinations of Antibodies against PfRH5 and Other Merozoite Antigens

(2012) Andrew R. Williams et al.   PLoS Pathogens

Super-Resolution Dissection of Coordinated Events during Malaria Parasite Invasion of the Human Erythrocyte

(2011) David T. Riglar et al.   Cell Host & Microbe

Molecular interactions and signaling mechanisms during erythrocyte invasion by malaria parasites

(2011) Deepak Gaur et al.   CURRENT OPINION IN MICROBIOLOGY

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum

(2011) Cécile Crosnier et al.   NATURE

Plasmodium falciparum Reticulocyte Binding-Like Homologue Protein 2 (PfRH2) Is a Key Adhesive Molecule Involved in Erythrocyte Invasion

(2011) Tajali Sahar et al.   PLoS One

Binding ofPlasmodiummerozoite proteins RON2 and AMA1 triggers commitment to invasion

(2011) Prakash Srinivasan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

(2011) Alexander D. Douglas et al.   Nature Communications

An EGF-like Protein Forms a Complex with PfRh5 and Is Required for Invasion of Human Erythrocytes by Plasmodium falciparum

(2011) Lin Chen et al.   PLoS Pathogens

Targeting protein–protein interactions for therapeutic intervention: a challenge for the future

(2010) Giovanna Zinzalla et al.   Future Medicinal Chemistry

Advances and challenges in malaria vaccine development

(2010) Peter D. Crompton et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinct External Signals Trigger Sequential Release of Apical Organelles during Erythrocyte Invasion by Malaria Parasites

(2010) Shailja Singh et al.   PLoS Pathogens

Novel Putative Glycosylphosphatidylinositol-Anchored Micronemal Antigen ofPlasmodium falciparumThat Binds to Erythrocytes

(2009) Louise Hinds et al.   EUKARYOTIC CELL

Erythrocyte Binding Protein PfRH5 Polymorphisms Determine Species-Specific Pathways of Plasmodium falciparum Invasion

(2008) Karen Hayton et al.   Cell Host & Microbe

Reticulocyte-binding protein homologue 5 – An essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum

(2008) Jake Baum et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY