Modulation of host central carbon metabolism and in situ glucose uptake by intracellular Trypanosoma cruzi amastigotes

Cardiac manifestations of parasitic diseases

(2017) Maria Carmo P Nunes et al.   HEART

Macrophages Promote Oxidative Metabolism To Drive Nitric Oxide Generation in Response to Trypanosoma cruzi

(2016) Sue-jie Koo et al.   INFECTION AND IMMUNITY

Subversion of Schwann Cell Glucose Metabolism byMycobacterium leprae

(2016) Rychelle Clayde Affonso Medeiros et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioenergetic profiling of Trypanosoma cruzi life stages using Seahorse extracellular flux technology

(2016) Sheena Shah-Simpson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The BENEFIT Trial: Where Do We Go from Here?

(2016) Bernard Pecoul et al.   PLoS Neglected Tropical Diseases

Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection

(2016) Yuan Li et al.   PLoS Pathogens

SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease

(2016) Xianxiu Wan et al.   PLoS Pathogens

Hepatic Bmal1 Regulates Rhythmic Mitochondrial Dynamics and Promotes Metabolic Fitness

(2015) David Jacobi et al.   Cell Metabolism

Mitochondrial dysfunction in skeletal muscle during experimental Chagas disease

(2015) Alejandra L. Báez et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM)

(2015) Jaime A. Costales et al.   Parasites & Vectors

Infection with Mycobacterium tuberculosis induces the Warburg effect in mouse lungs

(2015) Lanbo Shi et al.   Scientific Reports

Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease

(2015) Shilpi Khare et al.   PLoS Pathogens

Glucose metabolism inTrypanosoma cruzi

(2015) Dante A. Maugeri et al.   Essays in Biochemistry

Dysregulation of Autonomic Nervous System in Chagas’ Heart Disease Is Associated with Altered Adipocytokines Levels

(2015) João Marcos Barbosa-Ferreira et al.   PLoS One

Bioluminescence imaging of chronicTrypanosoma cruziinfections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection

(2014) Michael D. Lewis et al.   CELLULAR MICROBIOLOGY

The three-dimensional structure of the cytostome-cytopharynx complex ofTrypanosoma cruziepimastigotes

(2014) Carolina L. Alcantara et al.   JOURNAL OF CELL SCIENCE

Alamethicin Disrupts the Cholesterol Distribution in Dimyristoyl Phosphatidylcholine–Cholesterol Lipid Bilayers

(2014) Shuo Qian et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Beta Interferon Regulation of Glucose Metabolism Is PI3K/Akt Dependent and Important for Antiviral Activity against Coxsackievirus B3

(2014) J. D. Burke et al.   JOURNAL OF VIROLOGY

Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts

(2014) Kamil S. Sitarz et al.   MOLECULAR GENETICS AND METABOLISM

Shigellareroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth

(2014) David Kentner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Metabolomic Profiling of Acute Myocarditis Caused by Trypanosoma cruzi Infection

(2014) Núria Gironès et al.   PLoS Neglected Tropical Diseases

Alterations in Glucose Homeostasis in a Murine Model of Chagas Disease

(2013) Fnu Nagajyothi et al.   AMERICAN JOURNAL OF PATHOLOGY

Remodeling of Oxidative Energy Metabolism by Galactose Improves Glucose Handling and Metabolic Switching in Human Skeletal Muscle Cells

(2013) Eili Tranheim Kase et al.   PLoS One

Stimulation of de Novo Pyrimidine Synthesis by Growth Signaling Through mTOR and S6K1

(2013) I. Ben-Sahra et al.   SCIENCE

Quinolone-3-Diarylethers: A New Class of Antimalarial Drug

(2013) A. Nilsen et al.   Science Translational Medicine

Regulation of Glucose Transporter Translocation in Health and Diabetes

(2012) Jonathan S. Bogan   Annual Review of Biochemistry

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

Response of Adipose Tissue to Early Infection With Trypanosoma cruzi (Brazil Strain)

(2012) F. Nagajyothi et al.   JOURNAL OF INFECTIOUS DISEASES

Microscale oxygraphy reveals OXPHOS impairment in MRC mutant cells

(2012) F. Invernizzi et al.   MITOCHONDRION

A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

(2012) Min Yuan et al.   Nature Protocols

Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis

(2012) J. S. Doggett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes: Bioenergetics and Utilization in Safety Screening

(2012) Payal Rana et al.   TOXICOLOGICAL SCIENCES

New Insights into Cytosolic Glucose Levels during Differentiation of 3T3-L1 Fibroblasts into Adipocytes

(2011) Petra Brina Kovacic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Trypanosoma cruzi in adipose tissue in human chronic Chagas disease

(2011) Adaliene Versiani Matos Ferreira et al.   MICROBES AND INFECTION

Metabolomic Profiling from Formalin-Fixed, Paraffin-Embedded Tumor Tissue Using Targeted LC/MS/MS: Application in Sarcoma

(2011) Andrew D. Kelly et al.   PLoS One

Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection

(2011) Yongjun Yu et al.   TRENDS IN MICROBIOLOGY

Chagas disease

(2010) Anis Rassi et al.   LANCET

Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters

(2010) Gabriela Schumann Burkard et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Allotopic expression of mitochondrial-encoded genes in mammals: achieved goal, undemonstrated mechanism or impossible task?

(2010) Ester Perales-Clemente et al.   NUCLEIC ACIDS RESEARCH

Central carbon metabolism of Leishmania parasites

(2010) ELEANOR C. SAUNDERS et al.   PARASITOLOGY

Mitochondrial Complex III Defects Contribute to Inefficient Respiration and ATP Synthesis in the Myocardium of Trypanosoma cruzi–Infected Mice

(2009) Jian-Jun Wen et al.   ANTIOXIDANTS & REDOX SIGNALING

The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi

(2009) Todd A Minning et al.   BMC GENOMICS

Cytokine-dependent and–independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling

(2009) Jaime A Costales et al.   BMC GENOMICS

CD8+ T cells in Trypanosoma cruzi infection

(2009) Angel M Padilla et al.   CURRENT OPINION IN IMMUNOLOGY

Glucose uptake in the mammalian stages of Trypanosoma cruzi

(2009) Ariel M. Silber et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

GLUT1 and GLUT9 as major contributors to glucose influx in HepG2 cells identified by a high sensitivity intramolecular FRET glucose sensor

(2008) Hitomi Takanaga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Tissue-specific oxidative imbalance and mitochondrial dysfunction during Trypanosoma cruzi infection in mice

(2008) J WEN et al.   MICROBES AND INFECTION