Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model
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Title
Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model
Authors
Keywords
Hypoxia, Biochemical simulations, Phosphorylation, Simulation and modeling, Oxygen, Messenger RNA, Medical hypoxia, Protein expression
Journal
PLoS Computational Biology
Volume 13, Issue 1, Pages e1005272
Publisher
Public Library of Science (PLoS)
Online
2017-01-10
DOI
10.1371/journal.pcbi.1005272
References
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Note: Only part of the references are listed.- CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer
- (2016) Kipp Weiskopf et al. JOURNAL OF CLINICAL INVESTIGATION
- A computational model of cardiac fibroblast signaling predicts context-dependent drivers of myofibroblast differentiation
- (2016) A.C. Zeigler et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Transforming growth factor-beta 1 produced by vascular smooth muscle cells predicts fibrosis in the gastrocnemius of patients with peripheral artery disease
- (2016) Duy M. Ha et al. Journal of Translational Medicine
- CD47 regulates renal tubular epithelial cell self-renewal and proliferation following renal ischemia reperfusion
- (2016) Natasha M. Rogers et al. KIDNEY INTERNATIONAL
- Endothelial cells decode VEGF-mediated Ca2+signaling patterns to produce distinct functional responses
- (2016) David P. Noren et al. Science Signaling
- High-glucose environment increased thrombospondin-1 expression in keratinocytes via DNA hypomethylation
- (2016) Cheng-Che E. Lan et al. Translational Research
- Endothelial cells decode VEGF-mediated Ca2+signaling patterns to produce distinct functional responses
- (2016) David P. Noren et al. Science Signaling
- Hypoxia Induces Autophagy through Translational Up-Regulation of Lysosomal Proteins in Human Colon Cancer Cells
- (2016) Ming-Chih Lai et al. PLoS One
- HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction
- (2015) David Labrousse-Arias et al. CARDIOVASCULAR RESEARCH
- Thrombospondin-1-Based Antiangiogenic Therapy
- (2015) Jennifer N. Sims et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- Targeting the TGFβ pathway for cancer therapy
- (2015) Cindy Neuzillet et al. PHARMACOLOGY & THERAPEUTICS
- PADPIN: protein-protein interaction networks of angiogenesis, arteriogenesis, and inflammation in peripheral arterial disease
- (2015) Liang-Hui Chu et al. PHYSIOLOGICAL GENOMICS
- Modeling the interplay between the HIF-1 and p53 pathways in hypoxia
- (2015) Chun-Hong Zhou et al. Scientific Reports
- Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer
- (2015) Chen Zhao et al. PLoS Computational Biology
- Cyclic Pifithrin-α Sensitizes Wild Type p53 Tumor Cells to Antimicrotubule Agent–Induced Apoptosis
- (2015) Valentina Zuco et al. NEOPLASIA
- The Thrombospondin-1 Mimetic ABT-510 Increases the Uptake and Effectiveness of Cisplatin and Paclitaxel in a Mouse Model of Epithelial Ovarian Cancer
- (2015) Nicole E. Campbell et al. NEOPLASIA
- Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions
- (2014) Naveen S. Vasudev et al. ANGIOGENESIS
- Hypoxia represses microRNA biogenesis proteins in breast cancer cells
- (2014) Veronika Bandara et al. BMC CANCER
- Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis
- (2014) Joo-Hyeon Lee et al. CELL
- Small Molecules Targeting c-Myc Oncogene: Promising Anti-Cancer Therapeutics
- (2014) Bing-Jia Chen et al. International Journal of Biological Sciences
- Thrombospondin-1 Activation of Signal-Regulatory Protein- Stimulates Reactive Oxygen Species Production and Promotes Renal Ischemia Reperfusion Injury
- (2014) M. Yao et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Masking Epistasis Between MYC and TGF-β Pathways in Antiangiogenesis-Mediated Colon Cancer Suppression
- (2014) Michael Dews et al. JNCI-Journal of the National Cancer Institute
- Towards elucidating the connection between epithelial-mesenchymal transitions and stemness
- (2014) M. K. Jolly et al. Journal of the Royal Society Interface
- Current understanding of the thrombospondin-1 interactome
- (2014) Andrea Resovi et al. MATRIX BIOLOGY
- Thrombospondin-1 and CD47 regulation of cardiac, pulmonary and vascular responses in health and disease
- (2014) Natasha M. Rogers et al. MATRIX BIOLOGY
- The Self-Limiting Dynamics of TGF-β Signaling In Silico and In Vitro, with Negative Feedback through PPM1A Upregulation
- (2014) Junjie Wang et al. PLoS Computational Biology
- Thrombospondins, Potential Drug Targets for Cardiovascular Diseases
- (2013) Erja Mustonen et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
- (2013) E Mogilyansky et al. CELL DEATH AND DIFFERENTIATION
- Differential MicroRNA Expression Profiles in Peripheral Arterial Disease
- (2013) Philip W. Stather et al. Circulation-Cardiovascular Genetics
- TGFβ Signaling and Cardiovascular Diseases
- (2013) Evangelia Pardali et al. International Journal of Biological Sciences
- Angiogenic response to passive movement and active exercise in individuals with peripheral arterial disease
- (2013) B. Hoier et al. JOURNAL OF APPLIED PHYSIOLOGY
- A dynamic model of the hypoxia-inducible factor 1 (HIF-1 ) network
- (2013) L. K. Nguyen et al. JOURNAL OF CELL SCIENCE
- Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis
- (2013) Zhen Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Thrombospondin-1 mediates oncogenic Ras–induced senescence in premalignant lung tumors
- (2013) Kwan-Hyuck Baek et al. JOURNAL OF CLINICAL INVESTIGATION
- Temporal response of positive and negative regulators in response to acute and chronic exercise training in mice
- (2013) Sara A. Olenich et al. JOURNAL OF PHYSIOLOGY-LONDON
- Let-7g Improves Multiple Endothelial Functions Through Targeting Transforming Growth Factor-Beta and SIRT-1 Signaling
- (2013) Yi-Chu Liao et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF- superfamily network
- (2013) D. Nicklas et al. Journal of the Royal Society Interface
- MYC Degradation under Low O2Tension Promotes Survival by Evading Hypoxia-Induced Cell Death
- (2013) Waihay J. Wong et al. MOLECULAR AND CELLULAR BIOLOGY
- Erratum: Corrigendum: Global quantification of mammalian gene expression control
- (2013) Björn Schwanhäusser et al. NATURE
- BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors
- (2013) R Tsuchida et al. ONCOGENE
- TGF-Beta Suppresses VEGFA-Mediated Angiogenesis in Colon Cancer Metastasis
- (2013) Liying Geng et al. PLoS One
- Inhibition of Nuclear Factor of Activated T-Cells (NFAT) Suppresses Accelerated Atherosclerosis in Diabetic Mice
- (2013) Anna V. Zetterqvist et al. PLoS One
- Thrombospondin-1 Signaling through CD47 Inhibits Self-renewal by Regulating c-Myc and Other Stem Cell Transcription Factors
- (2013) Sukhbir Kaur et al. Scientific Reports
- Molecular Basis for the Regulation of Angiogenesis by Thrombospondin-1 and -2
- (2013) P. R. Lawler et al. Cold Spring Harbor Perspectives in Medicine
- A phase I study of ABT-510 plus bevacizumab in advanced solid tumors
- (2013) Hope E. Uronis et al. Cancer Medicine
- Therapeutic Angiogenesis in Critical Limb Ischemia
- (2012) Geoffrey O. Ouma et al. ANGIOLOGY
- Plasmin Triggers a Switch-Like Decrease in Thrombospondin-Dependent Activation of TGF-β1
- (2012) Lakshmi Venkatraman et al. BIOPHYSICAL JOURNAL
- MYC on the Path to Cancer
- (2012) Chi V. Dang CELL
- Functional Importance of Dicer Protein in the Adaptive Cellular Response to Hypoxia
- (2012) J. J. David Ho et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of Parenchymal CD47 Promotes Renal Ischemia-Reperfusion Injury
- (2012) N. M. Rogers et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration
- (2012) Jeffrey S. Heier et al. OPHTHALMOLOGY
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- (2011) Geert C. van Almen et al. AGING CELL
- p53-Responsive miR-194 Inhibits Thrombospondin-1 and Promotes Angiogenesis in Colon Cancers
- (2011) P. Sundaram et al. CANCER RESEARCH
- Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms
- (2011) Elena Piskounova et al. CELL
- Thrombospondin-1: Multiple Paths to Inflammation
- (2011) Zenaida Lopez-Dee et al. MEDIATORS OF INFLAMMATION
- MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1 Activity during Prolonged Hypoxia
- (2011) U. Bruning et al. MOLECULAR AND CELLULAR BIOLOGY
- Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells
- (2011) Sandrine Chamboredon et al. MOLECULAR BIOLOGY OF THE CELL
- ABT-898 Induces Tumor Regression and Prolongs Survival in a Mouse Model of Epithelial Ovarian Cancer
- (2011) N. Campbell et al. MOLECULAR CANCER THERAPEUTICS
- Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast
- (2011) C. Miller et al. Molecular Systems Biology
- Analysis of microRNA turnover in mammalian cells following Dicer1 ablation
- (2011) Michael P. Gantier et al. NUCLEIC ACIDS RESEARCH
- Reciprocal influence of the p53 and the hypoxic pathways
- (2011) A Sermeus et al. Cell Death & Disease
- Thrombospondin-1 Is a Plasmatic Marker of Peripheral Arterial Disease That Modulates Endothelial Progenitor Cell Angiogenic Properties
- (2010) David M. Smadja et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Silencing of Thrombospondin-1 Is Critical for Myc-Induced Metastatic Phenotypes in Medulloblastoma
- (2010) L. Zhou et al. CANCER RESEARCH
- The Myc-miR-17 92 Axis Blunts TGF Signaling and Production of Multiple TGF -Dependent Antiangiogenic Factors
- (2010) M. Dews et al. CANCER RESEARCH
- The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism
- (2010) Na Zhang et al. Cell Metabolism
- Thrombospondin-1 Inhibits VEGF Receptor-2 Signaling by Disrupting Its Association with CD47
- (2010) Sukhbir Kaur et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Role of Calcium/Calmodulin-Activated Calcineurin in Rapid and Slow Endocytosis at Central Synapses
- (2010) T. Sun et al. JOURNAL OF NEUROSCIENCE
- Negative Regulation of Tumor Suppressor p53 by MicroRNA miR-504
- (2010) Wenwei Hu et al. MOLECULAR CELL
- Thrombospondin-1 inhibition of vascular smooth muscle cell responses occurs via modulation of both cAMP and cGMP
- (2010) Mingyi Yao et al. PHARMACOLOGICAL RESEARCH
- Tristetraprolin regulates the stability of HIF-1α mRNA during prolonged hypoxia
- (2009) Tae Woo Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MicroRNAs As Novel Regulators of Angiogenesis
- (2009) Yajaira Suárez et al. CIRCULATION RESEARCH
- Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis
- (2009) Hong-li Yan et al. EMBO JOURNAL
- MicroRNA-125b is a novel negative regulator of p53
- (2009) M. T.N. Le et al. GENES & DEVELOPMENT
- Mechanisms of c-Myc Degradation by Nickel Compounds and Hypoxia
- (2009) Qin Li et al. PLoS One
- Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
- (2009) T.-C. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1
- (2009) S.-Y. Kang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Absolute quantification of microRNAs by using a universal reference
- (2009) U. Bissels et al. RNA
- NK cell apoptosis in coronary artery disease
- (2008) Wei Li et al. ATHEROSCLEROSIS
- Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences
- (2008) Arjun Raj et al. CELL
- Thrombospondins: from structure to therapeutics
- (2008) J. S. Isenberg et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Thrombospondins: from structure to therapeutics
- (2008) D. D. Roberts CELLULAR AND MOLECULAR LIFE SCIENCES
- A methodology for performing global uncertainty and sensitivity analysis in systems biology
- (2008) Simeone Marino et al. JOURNAL OF THEORETICAL BIOLOGY
- Transforming Growth Factor -Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth
- (2008) A. C. Daly et al. MOLECULAR AND CELLULAR BIOLOGY
- A positive role for Myc in TGFβ-induced Snail transcription and epithelial-to-mesenchymal transition
- (2008) A P Smith et al. ONCOGENE
- Modulation of Macrophage Activation State Protects Tissue from Necrosis during Critical Limb Ischemia in Thrombospondin-1-Deficient Mice
- (2008) Nicolas Bréchot et al. PLoS One
- Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis
- (2008) Y. Suarez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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