MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure

Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy

(2011) Andrew J. Boyle et al.   EXPERIMENTAL GERONTOLOGY

microRNA and aging: A novel modulator in regulating the aging network

(2010) Li-Hsin Chen et al.   AGEING RESEARCH REVIEWS

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

(2010) Matthias Hackl et al.   AGING CELL

The miR-17-92 Cluster of MicroRNAs Confers Tumorigenicity by Inhibiting Oncogene-Induced Senescence

(2010) L. Hong et al.   CANCER RESEARCH

Novel modulators of senescence, aging, and longevity: Small non-coding RNAs enter the stage

(2010) Johannes Grillari et al.   EXPERIMENTAL GERONTOLOGY

Tumorigenicity of the miR-17-92 cluster distilled

(2010) G. van Haaften et al.   GENES & DEVELOPMENT

Involvement of NADPH oxidase in age-associated cardiac remodeling

(2010) Mingyi Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

In situ detection of microRNAs in paraffin embedded, formalin fixed tissues and the co-localization of their putative targets

(2010) Gerard J. Nuovo   METHODS

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling

(2010) Paula A. da Costa Martins et al.   NATURE CELL BIOLOGY

microRNA Expression Patterns Reveal Differential Expression of Target Genes with Age

(2010) Nicole Noren Hooten et al.   PLoS One

Age-dependent alterations in fibrillar collagen content and myocardial diastolic function: role of SPARC in post-synthetic procollagen processing

(2009) Amy D. Bradshaw et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Absence of Thrombospondin-2 Causes Age-Related Dilated Cardiomyopathy

(2009) Melissa Swinnen et al.   CIRCULATION

Association Between Elevated Fibrosis Markers and Heart Failure in the Elderly

(2009) Eddy Barasch et al.   Circulation-Heart Failure

Regulation of chondrocytic phenotype by micro RNA 18a: Involvement ofCcn2/Ctgfas a major target gene

(2009) Toshihiro Ohgawara et al.   FEBS LETTERS

Alterations in microRNA expression in stress-induced cellular senescence

(2009) Guorong Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

MicroRNA MiR-17 retards tissue growth and represses fibronectin expression

(2009) Sze Wan Shan et al.   NATURE CELL BIOLOGY

Connective Tissue Growth Factor Overexpression in Cardiomyocytes Promotes Cardiac Hypertrophy and Protection against Pressure Overload

(2009) Anna N. Panek et al.   PLoS One

Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells

(2008) Shu Takakura et al.   CANCER SCIENCE

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Thrombospondin-1 Deficiency Accelerates Atherosclerotic Plaque Maturation in ApoE −/− Mice

(2008) Rute Moura et al.   CIRCULATION RESEARCH

miR-133 and miR-30 Regulate Connective Tissue Growth Factor

(2008) Rudy F. Duisters et al.   CIRCULATION RESEARCH

Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis

(2008) Xu Shi-Wen et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

(2008) Rajini Mudhasani et al.   JOURNAL OF CELL BIOLOGY

Changes in MicroRNA expression patterns in human fibroblasts after low-LET radiation

(2008) Olivier C. Maes et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation

(2008) Ran Brosh et al.   Molecular Systems Biology

Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis

(2008) Y. Suarez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA