Dissecting the Molecular Mechanisms of Neurodegenerative Diseases through Network Biology
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Title
Dissecting the Molecular Mechanisms of Neurodegenerative Diseases through Network Biology
Authors
Keywords
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Journal
Frontiers in Aging Neuroscience
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-05-29
DOI
10.3389/fnagi.2017.00166
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Note: Only part of the references are listed.- Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
- (2016) Steve Horvath et al. Aging-US
- Comparing Alzheimer’s and Parkinson’s diseases networks using graph communities structure
- (2016) Alberto Calderone et al. BMC Systems Biology
- The Cellular Phase of Alzheimer’s Disease
- (2016) Bart De Strooper et al. CELL
- Discovering New Genes in the Pathways of Common Sporadic Neurodegenerative Diseases: A Bioinformatics Approach
- (2016) Yong Hwan Kim et al. JOURNAL OF ALZHEIMERS DISEASE
- NAMPT protects against 6-hydroxydopamine-induced neurotoxicity in PC12 cells through modulating SIRT1 activity
- (2016) XIAO-DONG ZOU et al. Molecular Medicine Reports
- Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice
- (2016) Peter Langfelder et al. NATURE NEUROSCIENCE
- Common disease signatures from gene expression analysis in Huntington’s disease human blood and brain
- (2016) Eleni Mina et al. Orphanet Journal of Rare Diseases
- A transcriptional signature of Alzheimer’s disease is associated with a metastable subproteome at risk for aggregation
- (2016) Prajwal Ciryam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson’s disease etiology
- (2016) Simon G. Coetzee et al. Scientific Reports
- Integrative transcriptomic meta-analysis of Parkinson’s disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson’s disease
- (2016) Jose A. Santiago et al. Scientific Reports
- A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer’s Disease
- (2016) Shan Jiang et al. Frontiers in Aging Neuroscience
- Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington’s Disease
- (2016) Joseph R. Scarpa et al. PLoS Genetics
- Systems Nutrigenomics Reveals Brain Gene Networks Linking Metabolic and Brain Disorders
- (2016) Qingying Meng et al. EBioMedicine
- Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning
- (2015) Morgan E Levine et al. Aging-US
- Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients
- (2015) R. Fernandez-Santiago et al. EMBO Molecular Medicine
- Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses
- (2015) Anna Wilkaniec et al. JOURNAL OF NEUROCHEMISTRY
- Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial
- (2015) LANCET NEUROLOGY
- Reconfiguration of DNA methylation in aging
- (2015) Michele Zampieri et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus
- (2015) R S Desikan et al. MOLECULAR PSYCHIATRY
- Lithium Treatment in Patients With Huntington's Disease and Suicidal Behavior
- (2015) Michele Raja et al. MOVEMENT DISORDERS
- Epigenetic regulation of ageing: linking environmental inputs to genomic stability
- (2015) Bérénice A. Benayoun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Laying the foundations for disease-modifying therapies in PD
- (2015) Patrik Brundin et al. Nature Reviews Neurology
- Comparative pathway and network analysis of brain transcriptome changes during adult aging and in Parkinson's disease
- (2015) Enrico Glaab et al. NEUROBIOLOGY OF DISEASE
- Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice
- (2015) Alessandro Pristerà et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Network-based metaanalysis identifies HNF4A and PTBP1 as longitudinally dynamic biomarkers for Parkinson’s disease
- (2015) Jose A. Santiago et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson’s disease
- (2015) Harriet Keane et al. Scientific Reports
- A Systems Approach Identifies Networks and Genes Linking Sleep and Stress: Implications for Neuropsychiatric Disorders
- (2015) Peng Jiang et al. Cell Reports
- Peripheral Biomarkers of Parkinson’s Disease Progression and Pioglitazone Effects
- (2015) David K. Simon et al. Journal of Parkinsons Disease
- Motor and Cognitive Advantages Persist 12 Months After Exenatide Exposure in Parkinson’s Disease
- (2015) Iciar Aviles-Olmos et al. Journal of Parkinsons Disease
- Age, Sex, andAPOEε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span
- (2015) Clifford R. Jack et al. JAMA Neurology
- Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis
- (2015) Afroza Khanam Irin et al. Journal of Immunology Research
- Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells
- (2015) Karen L. Ring et al. Stem Cell Reports
- Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease
- (2014) Puneet Talwar et al. BMC GENOMICS
- A common gene expression signature in Huntington’s disease patient brain regions
- (2014) Andreas Neueder et al. BMC Medical Genomics
- Thiazolidinediones under preclinical and early clinical development for the treatment of Parkinson’s disease
- (2014) Anna R Carta et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity
- (2014) Julien Dusonchet et al. HUMAN MOLECULAR GENETICS
- Preclinical and Clinical Investigations of Mood Stabilizers for Huntington's Disease: What Have We Learned?
- (2014) Lisa Scheuing et al. International Journal of Biological Sciences
- Epigenetics of Aging and Aging-related Disease
- (2014) A. Brunet et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Identifying the Association Between Alzheimer’s Disease and Parkinson’s Disease Using Genome-Wide Association Studies and Protein-Protein Interaction Network
- (2014) Guiyou Liu et al. MOLECULAR NEUROBIOLOGY
- Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases
- (2014) M. Narayanan et al. Molecular Systems Biology
- Huntington disease: natural history, biomarkers and prospects for therapeutics
- (2014) Christopher A. Ross et al. Nature Reviews Neurology
- Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction
- (2014) Marie Orre et al. NEUROBIOLOGY OF AGING
- System-based approaches to decode the molecular links in Parkinson's disease and diabetes
- (2014) Jose A. Santiago et al. NEUROBIOLOGY OF DISEASE
- Targeting histone-modifications in Alzheimer's disease. What is the evidence that this is a promising therapeutic avenue?
- (2014) Andre Fischer NEUROPHARMACOLOGY
- A review of physical and cognitive interventions in aging
- (2014) P.D. Bamidis et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Network Analysis Identifies SOD2 mRNA as a Potential Biomarker for Parkinson's Disease
- (2014) Jose A. Santiago et al. PLoS One
- A network approach to clinical intervention in neurodegenerative diseases
- (2014) Jose A. Santiago et al. TRENDS IN MOLECULAR MEDICINE
- A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease
- (2014) Marc Brehme et al. Cell Reports
- The emerging role of nutrition in Parkinson's disease
- (2014) Stacey E. Seidl et al. Frontiers in Aging Neuroscience
- Genetics and genomics of Parkinson’s disease
- (2014) Michelle K Lin et al. Genome Medicine
- Molecular Evidence for the Inverse Comorbidity between Central Nervous System Disorders and Cancers Detected by Transcriptomic Meta-analyses
- (2014) Kristina Ibáñez et al. PLoS Genetics
- Complex Network-Driven View of Genomic Mechanisms Underlying Parkinson’s Disease: Analyses in Dorsal Motor Vagal Nucleus, Locus Coeruleus, and Substantia Nigra
- (2014) Beatriz Raposo Corradini et al. Biomed Research International
- Shared Mechanisms of Neurodegeneration in Alzheimer’s Disease and Parkinson’s Disease
- (2014) Anmu Xie et al. Biomed Research International
- The incorporation of epigenetics in artificial gene regulatory networks
- (2013) Alexander P. Turner et al. BIOSYSTEMS
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- Sirtuin deacetylases in neurodegenerative diseases of aging
- (2013) Adrianna Z Herskovits et al. CELL RESEARCH
- SIRT1 and SIRT2: emerging targets in neurodegeneration
- (2013) Gizem Donmez et al. EMBO Molecular Medicine
- Discovery of the neuroprotective effects of alvespimycin by computational prioritization of potential anti-parkinson agents
- (2013) Li Gao et al. FEBS Journal
- Exenatide and the treatment of patients with Parkinson’s disease
- (2013) Iciar Aviles-Olmos et al. JOURNAL OF CLINICAL INVESTIGATION
- A network approach to diagnostic biomarkers in progressive supranuclear palsy
- (2013) Jose A. Santiago et al. MOVEMENT DISORDERS
- Identification of Unstable Network Modules Reveals Disease Modules Associated with the Progression of Alzheimer’s Disease
- (2013) Masataka Kikuchi et al. PLoS One
- Integrative Network Analysis Unveils Convergent Molecular Pathways in Parkinson's Disease and Diabetes
- (2013) Jose A. Santiago et al. PLoS One
- Parkinson's disease in the nuclear age of neuroinflammation
- (2013) Yvonne M. Nolan et al. TRENDS IN MOLECULAR MEDICINE
- Shared dysregulated pathways lead to Parkinson's disease and diabetes
- (2013) Jose A. Santiago et al. TRENDS IN MOLECULAR MEDICINE
- An ERcentric view of Parkinson's disease
- (2013) Gabriela Mercado et al. TRENDS IN MOLECULAR MEDICINE
- Genes and pathways underlying regional and cell type changes in Alzheimer's disease
- (2013) Jeremy A Miller et al. Genome Medicine
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells
- (2012) Mahru C. An et al. Cell Stem Cell
- Huntington’s Disease and the Striatal Medium Spiny Neuron: Cell-Autonomous and Non-Cell-Autonomous Mechanisms of Disease
- (2012) Michelle E. Ehrlich Neurotherapeutics
- Integrating the Alzheimer's Disease Proteome and Transcriptome: A Comprehensive Network Model of a Complex Disease
- (2012) Peter Hallock et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Concerted Perturbation Observed in a Hub Network in Alzheimer’s Disease
- (2012) Dapeng Liang et al. PLoS One
- Action of RORs and their ligands in (patho)physiology
- (2012) Laura A. Solt et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Alternative α-synuclein transcript usage as a convergent mechanism in Parkinson's disease pathology
- (2012) Herve Rhinn et al. Nature Communications
- EpiRegNet: Constructing epigenetic regulatory network from high throughput gene expression data for humans
- (2011) Lily Yan Wang et al. Epigenetics
- Sodium valproate blocks the transforming growth factor (TGF)-β1 autocrine loop and attenuates the TGF-β1-induced collagen synthesis in a human hepatic stellate cell line
- (2011) Toshifumi Watanabe INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Depression in Parkinson disease—epidemiology, mechanisms and management
- (2011) Dag Aarsland et al. Nature Reviews Neurology
- Dynamic modularity in protein interaction networks predicts breast cancer outcome
- (2009) Ian W Taylor et al. NATURE BIOTECHNOLOGY
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network
- (2009) Bolan Linghu et al. GENOME BIOLOGY
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- A Systems Level Analysis of Transcriptional Changes in Alzheimer's Disease and Normal Aging
- (2008) J. A. Miller et al. JOURNAL OF NEUROSCIENCE
- Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons
- (2008) A. Schneider et al. JOURNAL OF NEUROSCIENCE
- Variations in DNA elucidate molecular networks that cause disease
- (2008) Yanqing Chen et al. NATURE
- Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling
- (2007) Min-Huei Liang et al. MOLECULAR AND CELLULAR NEUROSCIENCE
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