A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer’s Disease

Dysfunctional Pro-Ceramide, ER Stress, and Insulin/IGF Signaling Networks with Progression of Alzheimer's Disease

(2018) Suzanne M. de la Monte et al.   JOURNAL OF ALZHEIMERS DISEASE

Immune Profiling in Blood Identifies sTNF-R1 Performing Comparably Well as Biomarker Panels for Classification of Alzheimer's Disease Patients

(2018) Christoph Laske et al.   JOURNAL OF ALZHEIMERS DISEASE

GAD65, GAD67, and GABAT Immunostaining in Human Brain and Apparent GAD65 Loss in Alzheimer's Disease

(2018) Claudia Schwab et al.   JOURNAL OF ALZHEIMERS DISEASE

Differential Activation of Tumor Necrosis Factor Receptors Distinguishes between Brains from Alzheimer's Disease and Non-Demented Patients

(2017) Xin Cheng et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's Disease Genetic Risk Factor APOE-ε4 Also Affects Normal Brain Function

(2016) Amanda M. Di Battista et al.   Current Alzheimer Research

MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials

(2016) Xue Hua et al.   NEUROBIOLOGY OF AGING

Apolipoprotein E4 reduces evoked hippocampal acetylcholine release in adult mice

(2015) Eva Dolejší et al.   JOURNAL OF NEUROCHEMISTRY

Age, Sex, andAPOEε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span

(2015) Clifford R. Jack et al.   JAMA Neurology

Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease

(2014) Puneet Talwar et al.   BMC GENOMICS

Endoplasmic reticulum stress promotes amyloid-beta peptides production in RGC-5 cells

(2014) Bingqian Liu et al.   CELL STRESS & CHAPERONES

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical and pathologic presentation in Parkinson's disease by apolipoprotein e4 allele status

(2014) Sarah E. Monsell et al.   PARKINSONISM & RELATED DISORDERS

Genome-Wide Association Study of CSF Levels of 59 Alzheimer's Disease Candidate Proteins: Significant Associations with Proteins Involved in Amyloid Processing and Inflammation

(2014) John S. K. Kauwe et al.   PLoS Genetics

Thyroid hormone receptor and liver X receptor competitively up-regulate human selective Alzheimer’s disease indicator-1 gene expression at the transcriptional levels

(2013) Emi Ishida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased risk of developing dementia in patients with bipolar disorder: a nested matched case-control study

(2013) Kuan-Yi Wu et al.   BIPOLAR DISORDERS

TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys

(2013) Mychael V. Lourenco et al.   Cell Metabolism

Common Variants in Psychiatric Risk Genes Predict Brain Structure at Birth

(2013) R. C. Knickmeyer et al.   CEREBRAL CORTEX

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Acetyl-CoA the Key Factor for Survival or Death of Cholinergic Neurons in Course of Neurodegenerative Diseases

(2013) Andrzej Szutowicz et al.   NEUROCHEMICAL RESEARCH

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

(2013) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

A blood based 12-miRNA signature of Alzheimer disease patients

(2013) Petra Leidinger et al.   GENOME BIOLOGY

Involvement of endoplasmic reticulum stress in tauopathy

(2012) Yukako Sakagami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Retinoic acid protects cardiomyocytes from high glucose-induced apoptosis through inhibition of NF-κB signaling Pathway

(2012) Irina T. Nizamutdinova et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PPAR /RXR -Induced and CD36-Mediated Microglial Amyloid-  Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice

(2012) M. Yamanaka et al.   JOURNAL OF NEUROSCIENCE

Two gene co-expression modules differentiate psychotics and controls

(2012) C Chen et al.   MOLECULAR PSYCHIATRY

APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease

(2012) Andrew B. Wolf et al.   NEUROBIOLOGY OF AGING

A Gene Co-Expression Network in Whole Blood of Schizophrenia Patients Is Independent of Antipsychotic-Use and Enriched for Brain-Expressed Genes

(2012) Simone de Jong et al.   PLoS One

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

(2012) Purvesh Khatri et al.   PLoS Computational Biology

Epigenetic modifications in frontal cortex from Alzheimer's disease and bipolar disorder patients

(2012) J S Rao et al.   Translational Psychiatry

Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

(2011) C Dirk Keene et al.   CURRENT OPINION IN NEUROBIOLOGY

Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1

(2011) Filip Van Hauwermeiren et al.   CYTOKINE & GROWTH FACTOR REVIEWS

miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes

(2011) Harsh Dweep et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Is My Network Module Preserved and Reproducible?

(2011) Peter Langfelder et al.   PLoS Computational Biology

Genome-Wide Association of Familial Late-Onset Alzheimer's Disease Replicates BIN1 and CLU and Nominates CUGBP2 in Interaction with APOE

(2011) Ellen M. Wijsman et al.   PLoS Genetics

Patterns of microRNA expression in normal and early Alzheimer’s disease human temporal cortex: white matter versus gray matter

(2010) Wang-Xia Wang et al.   ACTA NEUROPATHOLOGICA

Gene Coexpression Network Topology of Cardiac Development, Hypertrophy, and Failure

(2010) Frederick E. Dewey et al.   Circulation-Cardiovascular Genetics

SHORT COMMUNICATION: Apolipoprotein E genotype and Cognition in Bipolar Disorder

(2010) Márcio Gerhardt Soeiro De Souza et al.   CNS Neuroscience & Therapeutics

Morphine Induces AMPA Receptor Internalization in Primary Hippocampal Neurons via Calcineurin-Dependent Dephosphorylation of GluR1 Subunits

(2010) A. Y. F. Kam et al.   JOURNAL OF NEUROSCIENCE

Deletion of M1 Muscarinic Acetylcholine Receptors Increases Amyloid Pathology In Vitro and In Vivo

(2010) A. A. Davis et al.   JOURNAL OF NEUROSCIENCE

The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE

(2010) Rita J. Guerreiro et al.   NEUROBIOLOGY OF AGING

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

(2010) Li Shen et al.   NEUROIMAGE

i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study

(2010) K. Zhang et al.   NUCLEIC ACIDS RESEARCH

Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease

(2010) D. A. Wolk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common variants conferring risk of schizophrenia: A pathway analysis of GWAS data

(2010) Peilin Jia et al.   SCHIZOPHRENIA RESEARCH

Genetic Control of Human Brain Transcript Expression in Alzheimer Disease

(2009) Jennifer A. Webster et al.   AMERICAN JOURNAL OF HUMAN GENETICS

MicroRNAs: novel therapeutic targets in neurodegenerative diseases

(2009) Reema Roshan et al.   DRUG DISCOVERY TODAY

Up-regulation of the α-secretase ADAM10 by retinoic acid receptors and acitretin

(2009) Frank Tippmann et al.   FASEB JOURNAL

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

(2009) S. E. Baranzini et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

New insights into brain BDNF function in normal aging and Alzheimer disease

(2008) Lucia Tapia-Arancibia et al.   BRAIN RESEARCH REVIEWS

Functional organization of the transcriptome in human brain

(2008) Michael C Oldham et al.   NATURE NEUROSCIENCE

Tensor-based morphometry as a neuroimaging biomarker for Alzheimer's disease: An MRI study of 676 AD, MCI, and normal subjects

(2008) Xue Hua et al.   NEUROIMAGE

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

(2008) W. S. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Geometric Interpretation of Gene Coexpression Network Analysis

(2008) Steve Horvath et al.   PLoS Computational Biology

Candidate Single-Nucleotide Polymorphisms From a Genomewide Association Study of Alzheimer Disease

(2007) Hao Li et al.   ARCHIVES OF NEUROLOGY