Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel

Erratum: Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity

(2016) Chang-lin Li et al.   CELL RESEARCH

Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli

(2016) Y. Yang et al.   JOURNAL OF NEUROSCIENCE

A Gain-of-Function Mutation in Nav1.6 in a Case of Trigeminal Neuralgia

(2016) Brian S Tanaka et al.   MOLECULAR MEDICINE

SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons

(2016) Qingjian Han et al.   NEURON

Group II mGluRs suppress hyperexcitability in mouse and human nociceptors

(2016) Steve Davidson et al.   PAIN

Pain regulation by non-neuronal cells and inflammation

(2016) R.-R. Ji et al.   SCIENCE

Glial Activation, A Common Mechanism Underlying Spinal Synaptic Plasticity?

(2016) Li-Jun Zhou et al.   Neuroscience Bulletin

Modulation of Nav1.8 by Lysophosphatidic Acid in the Induction of Bone Cancer Pain

(2016) Hai-Li Pan et al.   Neuroscience Bulletin

Human Nav1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons

(2015) Chongyang Han et al.   JOURNAL OF NEUROPHYSIOLOGY

The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4

(2015) Y. Li et al.   JOURNAL OF NEUROSCIENCE

Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade

(2015) Zhen-Zhong Xu et al.   NATURE MEDICINE

NaV1.9: a sodium channel linked to human pain

(2015) Sulayman D. Dib-Hajj et al.   NATURE REVIEWS NEUROSCIENCE

Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7

(2015) Michael S. Minett et al.   Nature Communications

A Monoclonal Antibody that Targets a NaV1.7 Channel Voltage Sensor for Pain and Itch Relief

(2014) Jun-Ho Lee et al.   CELL

Toll-Like Receptor 4 Signaling Contributes to Paclitaxel-Induced Peripheral Neuropathy

(2014) Yan Li et al.   JOURNAL OF PAIN

Painful and painless channelopathies

(2014) David L H Bennett et al.   LANCET NEUROLOGY

Voltage-Gated Sodium Channel Expression in Mouse DRG after SNI Leads to Re-Evaluation of Projections of Injured Fibers

(2014) Cédric J Laedermann et al.   Molecular Pain

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

(2014) Dmitry Usoskin et al.   NATURE NEUROSCIENCE

Human sensory neurons: Membrane properties and sensitization by inflammatory mediators

(2014) Steve Davidson et al.   PAIN

Global Nav1.7 Knockout Mice Recapitulate the Phenotype of Human Congenital Indifference to Pain

(2014) Jacinthe Gingras et al.   PLoS One

Pain without Nociceptors? Nav1.7-Independent Pain Mechanisms

(2014) Michael S. Minett et al.   Cell Reports

Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain

(2013) Cédric J. Laedermann et al.   JOURNAL OF CLINICAL INVESTIGATION

Knockdown of sodium channel NaV1.6 blocks mechanical pain and abnormal bursting activity of afferent neurons in inflamed sensory ganglia

(2013) Wenrui Xie et al.   PAIN

Activation of mammalian target of rapamycin contributes to pain nociception induced in rats by BmK I, a sodium channel-specific modulator

(2013) Feng Jiang et al.   Neuroscience Bulletin

Emerging role of Toll-like receptors in the control of pain and itch

(2012) Tong Liu et al.   Neuroscience Bulletin

Loss-of-function mutations in sodium channel Nav1.7 cause anosmia

(2011) Jan Weiss et al.   NATURE

Overcoming obstacles to developing new analgesics

(2010) Clifford J Woolf   NATURE MEDICINE

Nociceptor sensitization in pain pathogenesis

(2010) Michael S Gold et al.   NATURE MEDICINE

Animal models of pain: progress and challenges

(2009) Jeffrey S. Mogil   NATURE REVIEWS NEUROSCIENCE

Continuous  -Opioid Receptor Activation Reduces Neuronal Voltage-Gated Sodium Channel (NaV1.7) Levels through Activation of Protein Kinase C in Painful Diabetic Neuropathy

(2008) M. Chattopadhyay et al.   JOURNAL OF NEUROSCIENCE