Human Nav1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons
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Title
Human Nav1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons
Authors
Keywords
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Journal
JOURNAL OF NEUROPHYSIOLOGY
Volume 113, Issue 9, Pages 3172-3185
Publisher
American Physiological Society
Online
2015-03-19
DOI
10.1152/jn.00113.2015
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- Dynamic clamp with StdpC software
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- Transfection of rat or mouse neurons by biolistics or electroporation
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- A riluzole- and valproate-sensitive persistent sodium current contributes to the resting membrane potential and increases the excitability of sympathetic neurones
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- Changes in action potentials and intracellular ionic homeostasis in a ventricular cell model related to a persistent sodium current in SCN5A mutations underlying LQT3
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