Global Nav1.7 Knockout Mice Recapitulate the Phenotype of Human Congenital Indifference to Pain

A Monoclonal Antibody that Targets a NaV1.7 Channel Voltage Sensor for Pain and Itch Relief

(2014) Jun-Ho Lee et al.   CELL

Pain without Nociceptors? Nav1.7-Independent Pain Mechanisms

(2014) Michael S. Minett et al.   Cell Reports

Isoform Selective Voltage-Gated Sodium Channel Modulators and the Therapy of Pain

(2013) Marko Jukic et al.   CURRENT MEDICINAL CHEMISTRY

Voltage-Gated Sodium Channel in Grasshopper Mice Defends Against Bark Scorpion Toxin

(2013) A. H. Rowe et al.   SCIENCE

Membrane properties and electrogenesis in the distal axons of small dorsal root ganglion neurons in vitro

(2012) Dmytro V. Vasylyev et al.   JOURNAL OF NEUROPHYSIOLOGY

Sodium Channel Nav1.7 Is Essential for Lowering Heat Pain Threshold after Burn Injury

(2012) S. D. Shields et al.   JOURNAL OF NEUROSCIENCE

Expression of Nav1.7 in DRG Neurons Extends from Peripheral Terminals in the Skin to Central Preterminal Branches and Terminals in the Dorsal Horn

(2012) Joel A Black et al.   Molecular Pain

The NaV1.7 sodium channel: from molecule to man

(2012) Sulayman D. Dib-Hajj et al.   NATURE REVIEWS NEUROSCIENCE

TRPA1 Mediates Mechanical Sensitization in Nociceptors during Inflammation

(2012) Richard C. Lennertz et al.   PLoS One

Gain-of-function Nav1.8 mutations in painful neuropathy

(2012) C. G. Faber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons

(2012) Michael S. Minett et al.   Nature Communications

Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy

(2011) Catharina G. Faber et al.   ANNALS OF NEUROLOGY

Intra- and Interfamily Phenotypic Diversity in Pain Syndromes Associated with a Gain-of-Function Variant of NaV1.7

(2011) Mark Estación et al.   Molecular Pain

Are Voltage-Gated Sodium Channels on the Dorsal Root Ganglion Involved in the Development of Neuropathic Pain?

(2011) Wei Wang et al.   Molecular Pain

Loss-of-function mutations in sodium channel Nav1.7 cause anosmia

(2011) Jan Weiss et al.   NATURE

Differential Evolution of Voltage-Gated Sodium Channels in Tetrapods and Teleost Fishes

(2010) J. Widmark et al.   MOLECULAR BIOLOGY AND EVOLUTION

Pain perception is altered by a nucleotide polymorphism in SCN9A

(2010) F. Reimann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice

(2009) Sandra Leo et al.   BEHAVIOURAL BRAIN RESEARCH

Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas

(2008) Joel A. Black et al.   ANNALS OF NEUROLOGY

Cautionary insights on knockout mouse studies: The gene or not the gene?

(2008) Amy F. Eisener-Dorman et al.   BRAIN BEHAVIOR AND IMMUNITY

ProTx-II, a Selective Inhibitor of NaV1.7 Sodium Channels, Blocks Action Potential Propagation in Nociceptors

(2008) W. A. Schmalhofer et al.   MOLECULAR PHARMACOLOGY

Predictive validity of animal pain models? A comparison of the pharmacokinetic–pharmacodynamic relationship for pain drugs in rats and humans

(2008) G.T. Whiteside et al.   NEUROPHARMACOLOGY