THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors
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Title
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors
Authors
Keywords
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Journal
Nature Communications
Volume 8, Issue -, Pages 14290
Publisher
Springer Nature
Online
2017-01-30
DOI
10.1038/ncomms14290
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Note: Only part of the references are listed.- Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization
- (2016) Juan B. Rodríguez-Molina et al. MOLECULAR CELL
- Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors
- (2016) Tinghu Zhang et al. Nature Chemical Biology
- Feedback Activation of STAT3 as a Cancer Drug-Resistance Mechanism
- (2016) Chengguang Zhao et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma
- (2015) Ramona Crescenzo et al. CANCER CELL
- STAT3 the oncogene - still eluding therapy?
- (2015) Matthew S. Wake et al. FEBS Journal
- Belinostat in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma: Results of the Pivotal Phase II BELIEF (CLN-19) Study
- (2015) Owen A. O'Connor et al. JOURNAL OF CLINICAL ONCOLOGY
- Novel ALK inhibitors in clinical use and development
- (2015) Chaitanya Iragavarapu et al. Journal of Hematology & Oncology
- THZ1 Reveals Roles for Cdk7 in Co-transcriptional Capping and Pausing
- (2015) Kyle A. Nilson et al. MOLECULAR CELL
- New dimension in therapeutic targeting of BCL-2 family proteins
- (2015) Samaher Besbes et al. Oncotarget
- Molecular Pathogenesis of Peripheral T Cell Lymphoma
- (2015) Mamiko Sakata-Yanagimoto et al. Current Hematologic Malignancy Reports
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- How I treat the peripheral T-cell lymphomas
- (2014) A. J. Moskowitz et al. BLOOD
- Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma
- (2014) J. Iqbal et al. BLOOD
- Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor
- (2014) Camilla L. Christensen et al. CANCER CELL
- Therapeutic options in relapsed or refractory peripheral T-cell lymphoma
- (2014) Bertrand Coiffier et al. CANCER TREATMENT REVIEWS
- CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer
- (2014) Edmond Chipumuro et al. CELL
- Romidepsin for the treatment of relapsed/refractory peripheral T-cell lymphoma: pivotal study update demonstrates durable responses
- (2014) Bertrand Coiffier et al. Journal of Hematology & Oncology
- Exploring the IL-21–STAT3 Axis as Therapeutic Target for Sézary Syndrome
- (2014) Leslie van der Fits et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Cyclin-Dependent Kinase 7 Controls mRNA Synthesis by Affecting Stability of Preinitiation Complexes, Leading to Altered Gene Expression, Cell Cycle Progression, and Survival of Tumor Cells
- (2014) T. W. R. Kelso et al. MOLECULAR AND CELLULAR BIOLOGY
- Targeting transcription regulation in cancer with a covalent CDK7 inhibitor
- (2014) Nicholas Kwiatkowski et al. NATURE
- The microenvironment in T-cell lymphomas: Emerging themes
- (2013) Philippe Gaulard et al. SEMINARS IN CANCER BIOLOGY
- Utility of BCL2, PD1, and CD25 Immunohistochemical Expression in the Diagnosis of T-cell Lymphomas
- (2013) Dennis P. O’Malley et al. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Bortezomib in combination with CHOP as first-line treatment for patients with stage III/IV peripheral T-cell lymphomas: A multicentre, single-arm, phase 2 trial
- (2012) Seok Jin Kim et al. EUROPEAN JOURNAL OF CANCER
- New molecular insights into peripheral T cell lymphomas
- (2012) Stefano A. Pileri et al. JOURNAL OF CLINICAL INVESTIGATION
- TFIIH: when transcription met DNA repair
- (2012) Emmanuel Compe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- SomaticSTAT3Mutations in Large Granular Lymphocytic Leukemia
- (2012) Hanna L.M. Koskela et al. NEW ENGLAND JOURNAL OF MEDICINE
- Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas
- (2011) Camilla Pilati et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis
- (2010) Lydia Durant et al. IMMUNITY
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia
- (2009) Rong Chen et al. BLOOD
- Diagnostic and prognostic evaluation of phenotypic markers TRAF1, MUM1, BCL2 and CD15 in cutaneous CD30-positive lymphoproliferative disorders
- (2009) M.F. Benner et al. BRITISH JOURNAL OF DERMATOLOGY
- Cryptotanshinone Inhibits Constitutive Signal Transducer and Activator of Transcription 3 Function through Blocking the Dimerization in DU145 Prostate Cancer Cells
- (2008) D.-S. Shin et al. CANCER RESEARCH
- International Peripheral T-Cell and Natural Killer/T-Cell Lymphoma Study: Pathology Findings and Clinical Outcomes
- (2008) JOURNAL OF CLINICAL ONCOLOGY
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