Effect of methotrexate/vitamin B12 on DNA methylation as a potential factor in leukemia treatment-related neurotoxicity

Maternal folate depletion during early development and high fat feeding from weaning elicit similar changes in gene expression, but not in DNA methylation, in adult offspring

(2017) Jill A. McKay et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Prevalence and predictors of anxiety and depression after completion of chemotherapy for childhood acute lymphoblastic leukemia: A prospective longitudinal study

(2016) Alicia S. Kunin-Batson et al.   CANCER

Non-DHFR-mediated effects of methotrexate in osteosarcoma cell lines: epigenetic alterations and enhanced cell differentiation

(2016) Martin Sramek et al.   Cancer Cell International

Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients

(2016) Victoria J. Forster et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Gene promoter DNA methylation patterns have a limited role in orchestrating transcriptional changes in the fetal liver in response to maternal folate depletion during pregnancy

(2016) Jill A. McKay et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Organ-Specific Gene Expression Changes in the Fetal Liver and Placenta in Response to Maternal Folate Depletion

(2016) Jill McKay et al.   Nutrients

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936

(2015) Riccardo E Marioni et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Psychosocial and Neurocognitive Outcomes in Adult Survivors of Adolescent and Early Young Adult Cancer: A Report From the Childhood Cancer Survivor Study

(2015) Pinki K. Prasad et al.   JOURNAL OF CLINICAL ONCOLOGY

Neurocognitive outcomes in long-term survivors of childhood acute lymphoblastic leukemia treated on contemporary treatment protocols: A systematic review

(2015) Yin Ting Cheung et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Psychiatric disorders in 130 survivors of childhood cancer: Preliminary results of a semi-standardized interview

(2015) J. Bagur et al.   PEDIATRIC BLOOD & CANCER

Genomic DNA Hypomethylation Is Associated with Neural Tube Defects Induced by Methotrexate Inhibition of Folate Metabolism

(2015) Xiuwei Wang et al.   PLoS One

Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic and interleukin-6 genes

(2015) Therese M. Murphy et al.   PSYCHIATRIC GENETICS

The role of epigenetics in depression and suicide: A platform for gene–environment interactions

(2015) Laura E. Lockwood et al.   PSYCHIATRY RESEARCH

Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate

(2015) María C. de Andres et al.   ARTHRITIS RESEARCH & THERAPY

Aberrations in DNA methylation are detectable during remission of acute lymphoblastic leukemia and predict patient outcome

(2015) Sanne D van Otterdijk et al.   Epigenomics

The effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjects

(2015) Dieuwertje E. G. Kok et al.   Clinical Epigenetics

Methotrexate Restores Regulatory T Cell Function Through Demethylation of the FoxP3 Upstream Enhancer in Patients With Rheumatoid Arthritis

(2015) Adam P. Cribbs et al.   Arthritis & Rheumatology

A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia

(2014) A. V. Moorman et al.   BLOOD

Astrocytic abnormalities and global DNA methylation patterns in depression and suicide

(2014) C Nagy et al.   MOLECULAR PSYCHIATRY

S-adenosylmethionine Levels Regulate the Schwann Cell DNA Methylome

(2014) Marta Varela-Rey et al.   NEURON

Epigenetic modifications in the nervous system and their impact upon cognitive impairments

(2014) Andrii Rudenko et al.   NEUROPHARMACOLOGY

Severe neurotoxicity following intrathecal methotrexate with nitrous oxide sedation in a child with acute lymphoblastic leukemia

(2014) U. Löbel et al.   PEDIATRIC BLOOD & CANCER

Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in down syndrome

(2013) Meaghan J Jones et al.   BMC Medical Genomics

Post-weaning selenium and folate supplementation affects gene and protein expression and global DNA methylation in mice fed high-fat diets

(2013) Emma N Bermingham et al.   BMC Medical Genomics

Transcriptomic and epigenetic changes in early liver steatosis associated to obesity: Effect of dietary methyl donor supplementation

(2013) Paul Cordero et al.   MOLECULAR GENETICS AND METABOLISM

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Genetic and Non-Genetic Influences during Pregnancy on Infant Global and Site Specific DNA Methylation: Role for Folate Gene Variants and Vitamin B12

(2012) Jill A. McKay et al.   PLoS One

Diet induced epigenetic changes and their implications for health

(2011) J. A. McKay et al.   Acta Physiologica

Methylene tetrahydrofolate reductase gene polymorphisms and their association with methotrexate toxicity

(2011) Kalliopi P. Spyridopoulou et al.   Pharmacogenetics and Genomics

Therapeutic Drug Monitoring of Methotrexate in Cerebrospinal Fluid After Systemic High-Dose Infusion in Children: Can the Burden of Intrathecal Methotrexate be Reduced?

(2010) Andreas Niemann et al.   THERAPEUTIC DRUG MONITORING

Methotrexate-associated alterations of the folate and methyl-transfer pathway in the CSF of ALL patients with and without symptoms of neurotoxicity

(2008) Sandra Vezmar et al.   PEDIATRIC BLOOD & CANCER