Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in down syndrome

mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies

(2013) Antonella Caccamo et al.   AGING CELL

Atypical aging in down syndrome

(2013) Warren B. Zigman   Developmental Disabilities Research Reviews

Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies

(2013) Robert Lowe et al.   Epigenetics

Dynamic DNA methylation across diverse human cell lines and tissues

(2013) K. E. Varley et al.   GENOME RESEARCH

Charting a dynamic DNA methylation landscape of the human genome

(2013) Michael J. Ziller et al.   NATURE

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

(2013) Yun Liu et al.   NATURE BIOTECHNOLOGY

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

(2013) Magda E Price et al.   Epigenetics & Chromatin

Global DNA Hypermethylation in Down Syndrome Placenta

(2013) Shengnan Jin et al.   PLoS Genetics

Skeletal Muscle-Specific CPT1 Deficiency Elevates Lipotoxic Intermediates but Preserves Insulin Sensitivity

(2013) Wanchun Shi et al.   Journal of Diabetes Research

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome

(2012) A. Auinger et al.   BRITISH JOURNAL OF NUTRITION

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Factors underlying variable DNA methylation in a human community cohort

(2012) L. L. Lam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin

(2012) Zhao Zhong Chong et al.   PROGRESS IN NEUROBIOLOGY

A Skew-t space-varying regression model for the spectral analysis of resting state brain activity

(2012) Salimah Ismail et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome

(2011) Stefania Trazzi et al.   HUMAN MOLECULAR GENETICS

Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles

(2011) M G Loudin et al.   LEUKEMIA

Extensive epigenetic reprogramming in human somatic tissues between fetus and adult

(2011) Ryan KC Yuen et al.   Epigenetics & Chromatin

Evaluation of the Infinium Methylation 450K technology

(2011) Sarah Dedeurwaerder et al.   Epigenomics

Updated national birth prevalence estimates for selected birth defects in the United States, 2004-2006

(2010) Samantha E. Parker et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Altered DNA Methylation in Leukocytes with Trisomy 21

(2010) Kristi Kerkel et al.   PLoS Genetics

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma

(2008) Sanjukta Chakraborty et al.   BMC CANCER

Tuberous sclerosis complex proteins control axon formation

(2008) Y.-J. Choi et al.   GENES & DEVELOPMENT

Comprehensive high-throughput arrays for relative methylation (CHARM)

(2008) R. A. Irizarry et al.   GENOME RESEARCH

Rnd1 Regulates Axon Extension by Enhancing the Microtubule Destabilizing Activity of SCG10

(2008) Ying-Hua Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The TSC1-TSC2 Complex Is Required for Proper Activation of mTOR Complex 2

(2008) J. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of Tuberin in Neuronal Degeneration

(2008) Samy L. Habib et al.   NEUROCHEMICAL RESEARCH

DNA methylation impacts on learning and memory in aging

(2007) Liang Liu et al.   NEUROBIOLOGY OF AGING