Methylene tetrahydrofolate reductase gene polymorphisms and their association with methotrexate toxicity

Polymorphisms in Methotrexate Pathways: What Is Clinically Relevant, What Is Not, and What Is Promising

(2012) Guillermo Gervasini   CURRENT DRUG METABOLISM

An update on methotrexate

(2010) Juergen Braun et al.   CURRENT OPINION IN RHEUMATOLOGY

Homocysteine,MTHFR gene polymorphisms, and cardio-cerebrovascular risk

(2010) Elisabetta Trabetti   JOURNAL OF APPLIED GENETICS

Functional polymorphisms and methotrexate treatment outcome in recent-onset rheumatoid arthritis

(2010) Wouter M Kooloos et al.   PHARMACOGENOMICS

Meta- and Pooled Analyses of the Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism and Colorectal Cancer: A HuGE-GSEC Review

(2009) E. Taioli et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms

(2009) R.B. Warren et al.   BRITISH JOURNAL OF DERMATOLOGY

Advances in individual prediction of methotrexate toxicity: a review

(2009) Kjeld Schmiegelow   BRITISH JOURNAL OF HAEMATOLOGY

Genetics of human neural tube defects

(2009) N. D.E. Greene et al.   HUMAN MOLECULAR GENETICS

Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects

(2009) Lisa R. Treviño et al.   JOURNAL OF CLINICAL ONCOLOGY

Metaanalysis of Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms Affecting Methotrexate Toxicity

(2009) M. C. FISHER et al.   JOURNAL OF RHEUMATOLOGY

Pharmacogenetic study of 5,10-methylenetetrahydrofolate reductase C677T and thymidylate synthase 3R/2R gene polymorphisms and methotrexate-related toxicity in Chinese Han patients with inflammatory arthritis

(2008) Q-Y Zeng et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism

(2008) Petra Bohanec Grabar et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Decreased risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in patients with the 5,10-methylenetetrahydrofolate reductase 677TT genotype

(2008) Kyoko Sugimoto et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Influence of MTHFR and RFC1 Polymorphisms on Toxicities During Maintenance Chemotherapy for Childhood Acute Lymphoblastic Leukemia or Lymphoma

(2008) Noriko Shimasaki et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Drug Related Genetic Polymorphisms Affecting Adverse Reactions to Methotrexate, Vinblastine, Doxorubicin and Cisplatin in Patients With Urothelial Cancer

(2008) Norihiko Tsuchiya et al.   JOURNAL OF UROLOGY

Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX

(2008) S. L. Hider et al.   RHEUMATOLOGY

Folate Pathway Genetic Polymorphisms are Related to Attention Disorders in Childhood Leukemia Survivors

(2007) Kevin R. Krull et al.   JOURNAL OF PEDIATRICS