Non-DHFR-mediated effects of methotrexate in osteosarcoma cell lines: epigenetic alterations and enhanced cell differentiation

Advances in emerging drugs for osteosarcoma

(2015) Claudia Maria Hattinger et al.   EXPERT OPINION ON EMERGING DRUGS

Solid Tumor Differentiation Therapy – Is It Possible?

(2015) Filemon Dela cruz et al.   Oncotarget

E2F1 impairs all-trans retinoic acid-induced osteogenic differentiation of osteosarcoma via promoting ubiquitination-mediated degradation of RARα

(2014) Lei Zhang et al.   CELL CYCLE

Relationship between RFC gene expression and intracellular drug concentration in methotrexate-resistant osteosarcoma cells

(2014) J.J. Wang et al.   GENETICS AND MOLECULAR RESEARCH

LOX/COX inhibitors enhance the antineoplastic effects of all-trans retinoic acid in osteosarcoma cell lines

(2014) Miroslava Krzyzankova et al.   TUMOR BIOLOGY

Mechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3) in acute promyelocytic leukemia

(2013) Akihiro Tomita et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Methotrexate-Induced Decrease in Embryonic 5-Methyl-Tetrahydrofolate Is Irreversible with Leucovorin Supplementation

(2013) Tseng-Ting Kao et al.   Zebrafish

Folate and DNA Methylation: A Review of Molecular Mechanisms and the Evidence for Folate's Role

(2012) Krista S. Crider et al.   Advances in Nutrition

Reduction of Fas/CD95 Promoter Methylation, Upregulation of Fas Protein, and Enhancement of Sensitivity to Apoptosis in Cutaneous T-Cell Lymphoma

(2010) Jianqiang Wu et al.   ARCHIVES OF DERMATOLOGY

The sequence of application of methotrexate and histone deacetylase inhibitors determines either a synergistic or an antagonistic response in childhood acute lymphoblastic leukemia cells

(2010) L Bastian et al.   LEUKEMIA

Inhibition of histone deacetylase activity is a novel function of the antifolate drug methotrexate

(2009) Pei-Ming Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High-dose Methotrexate in Pediatric Oncology—Back to Bench From Bedside for a While?

(2009) Jaroslav Sterba et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences

(2009) S. J. Diede et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines

(2008) Renata Veselska et al.   BMC CANCER

High-Dose Methotrexate in Osteosarcoma: Let the Questions Surcease—Time for Final Acceptance

(2008) Norman Jaffe et al.   JOURNAL OF CLINICAL ONCOLOGY

Retinoic acid syndrome: a review

(2008) E. Patatanian et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Mechanisms of antifolate resistance and methotrexate efficacy in leukemia cells

(2008) Alan Kambiz Fotoohi et al.   LEUKEMIA & LYMPHOMA

Methotrexate-associated alterations of the folate and methyl-transfer pathway in the CSF of ALL patients with and without symptoms of neurotoxicity

(2008) Sandra Vezmar et al.   PEDIATRIC BLOOD & CANCER