Maternal folate depletion during early development and high fat feeding from weaning elicit similar changes in gene expression, but not in DNA methylation, in adult offspring

Gene promoter DNA methylation patterns have a limited role in orchestrating transcriptional changes in the fetal liver in response to maternal folate depletion during pregnancy

(2016) Jill A. McKay et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Transcription factors as readers and effectors of DNA methylation

(2016) Heng Zhu et al.   NATURE REVIEWS GENETICS

Organ-Specific Gene Expression Changes in the Fetal Liver and Placenta in Response to Maternal Folate Depletion

(2016) Jill McKay et al.   Nutrients

Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90+ study

(2015) T. Nevalainen et al.   AGE

Global DNA methylation was changed by a maternal high-lipid, high-energy diet during gestation and lactation in male adult mice liver

(2015) Huan-Ling Yu et al.   BRITISH JOURNAL OF NUTRITION

Function and information content of DNA methylation

(2015) Dirk Schübeler   NATURE

DNA methylation pathways and their crosstalk with histone methylation

(2015) Jiamu Du et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

WikiPathways: capturing the full diversity of pathway knowledge

(2015) Martina Kutmon et al.   NUCLEIC ACIDS RESEARCH

High-fat diet caused widespread epigenomic differences on hepatic methylome in rat

(2015) Yukun Zhang et al.   PHYSIOLOGICAL GENOMICS

Maternal folate deficiency and metabolic dysfunction in offspring

(2015) Jill A. McKay et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis

(2015) Danielle L. Ippolito et al.   TOXICOLOGICAL SCIENCES

PathVisio 3: An Extendable Pathway Analysis Toolbox

(2015) Martina Kutmon et al.   PLoS Computational Biology

Maternal Supplementation with Folic Acid and Other Vitamins and Risk of Leukemia in Offspring

(2014) Catherine Metayer et al.   EPIDEMIOLOGY

Erythrocyte folate concentrations, CpG methylation at genomically imprinted domains, and birth weight in a multiethnic newborn cohort

(2014) Cathrine Hoyo et al.   Epigenetics

Identification of master genes involved in liver key functions through transcriptomics and epigenomics of methyl donor deficiency in rat: Relevance to nonalcoholic liver disease

(2014) Gaili Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Metabolic effects of a high-fat diet post-weaning after low maternal dietary folate during pregnancy and lactation

(2014) Jill A. McKay et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Maternal Dietary Intake of Folate and Vitamins B6 and B12 During Pregnancy and Risk of Childhood Brain Tumors

(2014) Kathryn R. Greenop et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Genome-Wide Methylation and Gene Expression Changes in Newborn Rats following Maternal Protein Restriction and Reversal by Folic Acid

(2014) Gioia Altobelli et al.   PLoS One

Prevention of congenital malformations and other adverse pregnancy outcomes with 4.0 mg of folic acid: community-based randomized clinical trial in Italy and the Netherlands

(2014) Renata Bortolus et al.   BMC Pregnancy and Childbirth

Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer

(2013) Marta Kulis et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Correction of unexpected distributions of P values from analysis of whole genome arrays by rectifying violation of statistical assumptions

(2013) Sheila J Barton et al.   BMC GENOMICS

Post-weaning selenium and folate supplementation affects gene and protein expression and global DNA methylation in mice fed high-fat diets

(2013) Emma N Bermingham et al.   BMC Medical Genomics

Gene set analysis methods: statistical models and methodological differences

(2013) H. Maciejewski   BRIEFINGS IN BIOINFORMATICS

Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort

(2013) Sajin Bae et al.   Epigenetics

Maternal folate depletion and high-fat feeding from weaning affects DNA methylation and DNA repair in brain of adult offspring

(2013) Sabine A. S. Langie et al.   FASEB JOURNAL

Comparative analysis of gene expression profiles of acute hepatic failure and that of liver regeneration in rat

(2013) Cunshuan Xu et al.   GENE

Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children

(2013) Pål Surén et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Transcriptomic and epigenetic changes in early liver steatosis associated to obesity: Effect of dietary methyl donor supplementation

(2013) Paul Cordero et al.   MOLECULAR GENETICS AND METABOLISM

Effect of maternal and postweaning folic acid supplementation on global and gene-specific DNA methylation in the liver of the rat offspring

(2013) Karen K. Y. Sie et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Enhancers: five essential questions

(2013) Len A. Pennacchio et al.   NATURE REVIEWS GENETICS

Gene Expression in Brain and Liver Produced by Three Different Regimens of Alcohol Consumption in Mice: Comparison with Immune Activation

(2013) Elizabeth Osterndorff-Kahanek et al.   PLoS One

Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study

(2012) Rebecca J Schmidt et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

An evaluation of two-channel ChIP-on-chip and DNA methylation microarray normalization strategies

(2012) Michiel E Adriaens et al.   BMC GENOMICS

Folic acid supplementation, MTHFR and MTRR polymorphisms, and the risk of childhood leukemia: the ESCALE study (SFCE)

(2012) Alicia Amigou et al.   CANCER CAUSES & CONTROL

Maternal Use of Folic Acid and Other Supplements and Risk of Childhood Brain Tumors

(2012) E. Milne et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Metabolic Syndrome in Adolescence

(2012) Stamatis P. Efstathiou et al.   CIRCULATION

Standardization and quality controls for the methylated DNA immunoprecipitation technique

(2012) Sofia Lisanti et al.   Epigenetics

Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism

(2012) Volodymyr Tryndyak et al.   FASEB JOURNAL

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Maternal Dietary Intake of Folate and Vitamins B6 and B12 During Pregnancy and the Risk of Childhood Acute Lymphoblastic Leukemia

(2012) Helen D. Bailey et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Folate depletion changes gene expression of fatty acid metabolism, DNA synthesis, and circadian cycle in male mice

(2012) Jacques Champier et al.   NUTRITION RESEARCH

Effect of high doses of folic acid supplementation in early pregnancy on child neurodevelopment at 18 months of age: the mother–child cohort ‘Rhea’ study in Crete, Greece

(2012) Leda Chatzi et al.   PUBLIC HEALTH NUTRITION

Mechanisms underlying the developmental origins of disease

(2012) Malgorzata S. Martin-Gronert et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

(2012) Purvesh Khatri et al.   PLoS Computational Biology

Protein and folic acid content in the maternal diet determine lipid metabolism and response to high-fat feeding in rat progeny in an age-dependent manner

(2011) Agata Chmurzynska et al.   Genes and Nutrition

Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer

(2011) G. C. Hon et al.   GENOME RESEARCH

Folic Acid Supplements in Pregnancy and Severe Language Delay in Children

(2011) Christine Roth et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Long-term adaptation of global transcription and metabolism in the liver of high-fat diet-fed C57BL/6J mice

(2011) Gyeong-Min Do et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Maternal folate supply and sex influence gene-specific DNA methylation in the fetal gut

(2011) Jill A. McKay et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Blood as a surrogate marker for tissue-specific DNA methylation and changes due to folate depletion in post-partum female mice

(2011) Jill A. McKay et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Increased methylation variation in epigenetic domains across cancer types

(2011) Kasper Daniel Hansen et al.   NATURE GENETICS

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains

(2011) Benjamin P Berman et al.   NATURE GENETICS

Gene Expression in Livers of BALB/C and C57BL/6J Mice Fed a High-Fat Diet

(2011) Satomi Nishikawa et al.   TOXICOLOGIC PATHOLOGY

New Insights from Rodent Models of Fatty Liver Disease

(2010) Jacquelyn J. Maher   ANTIOXIDANTS & REDOX SIGNALING

Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics

(2010) Alexander Link et al.   BIOCHEMICAL PHARMACOLOGY

Folate depletion during pregnancy and lactation reduces genomic DNA methylation in murine adult offspring

(2010) Jill A. McKay et al.   Genes and Nutrition

Folic acid to reduce neonatal mortality from neural tube disorders

(2010) H. Blencowe et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease

(2010) Irina A. Kirpich et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Animal models of nonalcoholic fatty liver disease

(2010) Lionel Hebbard et al.   Nature Reviews Gastroenterology & Hepatology

Finding the Right Questions: Exploratory Pathway Analysis to Enhance Biological Discovery in Large Datasets

(2010) Thomas Kelder et al.   PLOS BIOLOGY

Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction

(2009) Luigi Bouchard et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Antenatal Micronutrient Supplementation Reduces Metabolic Syndrome in 6- to 8-Year-Old Children in Rural Nepal

(2009) Christine P. Stewart et al.   JOURNAL OF NUTRITION

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

arrayQualityMetrics—a bioconductor package for quality assessment of microarray data

(2008) Audrey Kauffmann et al.   BIOINFORMATICS

Gene-set approach for expression pattern analysis

(2008) D. Nam et al.   BRIEFINGS IN BIOINFORMATICS

Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions

(2008) K. De Preter et al.   NUCLEIC ACIDS RESEARCH