Cystatin C as a potential therapeutic mediator against Parkinson’s disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units

Help-me signaling: Non-cell autonomous mechanisms of neuroprotection and neurorecovery

(2017) Changhong Xing et al.   PROGRESS IN NEUROBIOLOGY

Oridonin induces autophagy via inhibition of glucose metabolism in p53-mutated colorectal cancer cells

(2017) Zhuo Yao et al.   Cell Death & Disease

Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease

(2016) S.-M. Oh et al.   EMBO Molecular Medicine

Pericytes of the neurovascular unit: key functions and signaling pathways

(2016) Melanie D Sweeney et al.   NATURE NEUROSCIENCE

The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases

(2016) Matthew Redmann et al.   Aging and Disease

Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux

(2015) Sandy Giuliano et al.   Autophagy

A missense variant in CST3 exerts a recessive effect on susceptibility to age-related macular degeneration resembling its association with Alzheimer’s disease

(2015) Joe M. Butler et al.   HUMAN GENETICS

Inhibition of Mitochondrial Clearance and Cu/Zn-SOD Activity Enhance 6-Hydroxydopamine-Induced Neuronal Apoptosis

(2015) Sua In et al.   MOLECULAR NEUROBIOLOGY

Botanical Drug Puerarin Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Neurotoxicity via Upregulating Mitochondrial Enzyme Arginase-2

(2015) Jia Zhao et al.   MOLECULAR NEUROBIOLOGY

Tetramethylpyrazine Promotes Migration of Neural Precursor Cells via Activating the Phosphatidylinositol 3-Kinase Pathway

(2015) Xiangying Kong et al.   MOLECULAR NEUROBIOLOGY

Contra-directional Coupling of Nur77 and Nurr1 in Neurodegeneration: A Novel Mechanism for Memantine-Induced Anti-inflammation and Anti-mitochondrial Impairment

(2015) Xiaobo Wei et al.   MOLECULAR NEUROBIOLOGY

Increased CSF biomarkers of angiogenesis in Parkinson disease

(2015) Shorena Janelidze et al.   NEUROLOGY

α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation

(2015) Shijun Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Netrin-5 is highly expressed in neurogenic regions of the adult brain

(2015) Satoru Yamagishi et al.   Frontiers in Cellular Neuroscience

Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases

(2015) Miguel Chin-Chan et al.   Frontiers in Cellular Neuroscience

Scaffolding protein Homer1a protects against NMDA-induced neuronal injury

(2015) Y Wang et al.   Cell Death & Disease

Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration

(2015) J Zhang et al.   Cell Death & Disease

Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons

(2015) J C Koch et al.   Cell Death & Disease

Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia

(2015) Chuanhong Wu et al.   Scientific Reports

Limb Ischemic Perconditioning Attenuates Blood-Brain Barrier Disruption by Inhibiting Activity of MMP-9 and Occludin Degradation after Focal Cerebral Ischemia

(2015) Changhong Ren et al.   Aging and Disease

Neuroinflammation in Parkinson’s disease and its potential as therapeutic target

(2015) Qinqin Wang et al.   Translational Neurodegeneration

The neurovascular unit - concept review

(2014) V. Muoio et al.   Acta Physiologica

Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment

(2014) Anne-Maria Poehler et al.   Autophagy

Engineering a vascular endothelial growth factor 165-binding heparan sulfate for vascular therapy

(2014) Chunming Wang et al.   BIOMATERIALS

Neurons Limit Angiogenesis by Titrating VEGF in Retina

(2014) Keisuke Okabe et al.   CELL

The Ephrin-A5/EphA4 Interaction Modulates Neurogenesis and Angiogenesis by the p-Akt and p-ERK Pathways in a Mouse Model of TLE

(2014) Yi Shu et al.   MOLECULAR NEUROBIOLOGY

Interactions of Oxidative Stress and Neurovascular Inflammation in the Pathogenesis of Traumatic Brain Injury

(2014) P. M. Abdul-Muneer et al.   MOLECULAR NEUROBIOLOGY

PEGylated rhFGF-2 Conveys Long-term Neuroprotection and Improves Neuronal Function in a Rat Model of Parkinson’s Disease

(2014) Guanghui Zhu et al.   MOLECULAR NEUROBIOLOGY

Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons

(2014) Franziska Richter et al.   NEUROBIOLOGY OF DISEASE

Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling

(2014) Bruno P. Carreira et al.   Frontiers in Cellular Neuroscience

Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity

(2014) S Watanabe et al.   Cell Death & Disease

Vascular endothelial growth factors (VEGFs) and stroke

(2013) David A. Greenberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nuclear Import and Export Signals Control the Subcellular Localization of Nurr1 Protein in Response to Oxidative Stress

(2013) Ángel Juan García-Yagüe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuation of Early Brain Injury and Learning Deficits Following Experimental Subarachnoid Hemorrhage Secondary to Cystatin C: Possible Involvement of the Autophagy Pathway

(2013) Yizhi Liu et al.   MOLECULAR NEUROBIOLOGY

Autophagy Contributes to Leaf Starch Degradation

(2013) Y. Wang et al.   PLANT CELL

Supraphysiological doses of performance enhancing anabolic-androgenic steroids exert direct toxic effects on neuron-like cells

(2013) John R. Basile et al.   Frontiers in Cellular Neuroscience

Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity

(2013) J-T Kim et al.   Cell Death & Disease

Exogenous Nurr1 gene expression in electrically-stimulated human MSCs and the induction of neurogenesis

(2012) Ji Sun Park et al.   BIOMATERIALS

Alpha-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson’s disease

(2012) Weilin Xie et al.   JOURNAL OF NEUROCHEMISTRY

Opposing Roles of Synaptic and Extrasynaptic NMDA Receptor Signaling in Cocultured Striatal and Cortical Neurons

(2012) A. M. Kaufman et al.   JOURNAL OF NEUROSCIENCE

α-Synuclein Elevation in Human Neurodegenerative Diseases: Experimental, Pathogenetic, and Therapeutic Implications

(2012) Ayse Ulusoy et al.   MOLECULAR NEUROBIOLOGY

β-Catenin Loss in Hepatocytes Promotes Hepatocellular Cancer after Diethylnitrosamine and Phenobarbital Administration to Mice

(2012) Prince Kwaku Awuah et al.   PLoS One

Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining

(2012) Inês Palmela et al.   Frontiers in Cellular Neuroscience

Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system

(2012) Lin Zheng et al.   Translational Neurodegeneration

Vascular endothelial growth factor is upregulated by l-dopa in the parkinsonian brain: implications for the development of dyskinesia

(2011) K. Elisabet Ohlin et al.   BRAIN

MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression

(2011) Jian-Hong Fang et al.   HEPATOLOGY

Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism

(2011) Zhaohui Liu et al.   PHARMACOLOGICAL RESEARCH

Nuclear Receptors Nur77 and Nurr1 Modulate Mesenchymal Stromal Cell Migration

(2011) Marijke W. Maijenburg et al.   STEM CELLS AND DEVELOPMENT

Synphilin-1 attenuates neuronal degeneration in the A53T  -synuclein transgenic mouse model

(2010) W. W. Smith et al.   HUMAN MOLECULAR GENETICS

VEGF stimulates PKD-mediated CREB-dependent orphan nuclear receptor Nurr1 expression: Role in VEGF-induced angiogenesis

(2010) Dezheng Zhao et al.   INTERNATIONAL JOURNAL OF CANCER

A53T-Alpha-Synuclein Overexpression Impairs Dopamine Signaling and Striatal Synaptic Plasticity in Old Mice

(2010) Alexander Kurz et al.   PLoS One

Novel and Conventional Biomarkers for Prediction of Incident Cardiovascular Events in the Community

(2009) Olle Melander   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Early involvement of the cerebral cortex in Parkinson's disease: Convergence of multiple metabolic defects

(2009) Isidre Ferrer   PROGRESS IN NEUROBIOLOGY