The Ephrin-A5/EphA4 Interaction Modulates Neurogenesis and Angiogenesis by the p-Akt and p-ERK Pathways in a Mouse Model of TLE

In Vivo Expression of EphrinA5-Fc in Mice Results in Cephalic Neural Crest Agenesis and Craniofacial Abnormalities

(2014) Hyuna Noh et al.   MOLECULES AND CELLS

The Potential of Antiseizure Drugs and Agents that Act on Novel Molecular Targets as Antiepileptogenic Treatments

(2014) Rafal M. Kaminski et al.   Neurotherapeutics

Participation of bone marrow-derived cells in hippocampal vascularization after status epilepticus

(2014) Simone A. Romariz et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Altered expression of hypoxia-Inducible factor-1α participates in the epileptogenesis in animal models

(2014) Li Jie et al.   SYNAPSE

EphrinA/EphA-induced ectodomain shedding of neural cell adhesion molecule regulates growth cone repulsion through ADAM10 metalloprotease

(2013) Leann H. Brennaman et al.   JOURNAL OF NEUROCHEMISTRY

Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid

(2013) Pishan Chang et al.   NEUROBIOLOGY OF DISEASE

The PI3K/Akt and ERK1/2 signaling pathways mediate the erythropoietin-modulated calcium influx in kainic acid-induced epilepsy

(2013) Honghua Zheng et al.   NEUROREPORT

Discovery and Characterization of a Novel Cyclic Peptide That Effectively Inhibits Ephrin Binding to the EphA4 Receptor and Displays Anti-Angiogenesis Activity

(2013) Xiaofeng Han et al.   PLoS One

Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5

(2013) Kai Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ephrin-A5 deficiency alters sensorimotor and monoaminergic development

(2012) Michal Sheleg et al.   BEHAVIOURAL BRAIN RESEARCH

Whole transcriptome analysis of the hippocampus: toward a molecular portrait of epileptogenesis

(2012) Oswaldo K Okamoto et al.   BMC GENOMICS

Pentylenetetrazole-induced seizures cause acute, but not chronic, mTOR pathway activation in rat

(2012) Bo Zhang et al.   EPILEPSIA

EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion

(2012) Arend H. Sikkema et al.   NEURO-ONCOLOGY

Vascular endothelial growth factor regulates adult hippocampal cell proliferation through MEK/ERK- and PI3K/Akt-dependent signaling

(2012) Neil M. Fournier et al.   NEUROPHARMACOLOGY

Ephrin-A1-Mediated Dopaminergic Neurogenesis and Angiogenesis in a Rat Model of Parkinson's Disease

(2012) Xuefeng Jing et al.   PLoS One

A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke

(2012) J. J. Overman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knockdown of Ephrin-A5 Expression by 40% Does not Affect Motor Axon Growth or Migration into the Chick Hindlimb

(2011) Robert S. Winning et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Induction of Angiogenesis and Modulation of Vascular Endothelial Growth Factor Receptor-2 by Simvastatin After Traumatic Brain Injury

(2011) Hongtao Wu et al.   NEUROSURGERY

EphA4 Blockers Promote Axonal Regeneration and Functional Recovery Following Spinal Cord Injury in Mice

(2011) Yona Goldshmit et al.   PLoS One

Pathway-specific engagement of ephrinA5-EphA4/EphA5 system of the substantia nigra pars reticulata in cocaine-induced responses

(2011) K. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways

(2010) Bruno de Araújo Herculano et al.   BEHAVIOURAL BRAIN RESEARCH

Behavioral and genetic investigations of low exploratory behavior in Il18r1−/− mice: We can’t always blame it on the targeted gene

(2010) Amy F. Eisener-Dorman et al.   BRAIN BEHAVIOR AND IMMUNITY

Activation of ERK by spontaneous seizures in neural progenitors of the dentate gyrus in a mouse model of epilepsy

(2010) Yi Li et al.   EXPERIMENTAL NEUROLOGY

Estradiol-Induced Object Memory Consolidation in Middle-Aged Female Mice Requires Dorsal Hippocampal Extracellular Signal-Regulated Kinase and Phosphatidylinositol 3-Kinase Activation

(2010) L. Fan et al.   JOURNAL OF NEUROSCIENCE

The Developmental Stage of Dentate Granule Cells Dictates Their Contribution to Seizure-Induced Plasticity

(2010) M. M. Kron et al.   JOURNAL OF NEUROSCIENCE

Evidence of angiogenic vessels in Alzheimer’s disease

(2009) Brinda S. Desai et al.   JOURNAL OF NEURAL TRANSMISSION

Vascular changes in epilepsy: functional consequences and association with network plasticity in pilocarpine-induced experimental epilepsy

(2009) X.E. Ndode-Ekane et al.   NEUROSCIENCE

Cautionary insights on knockout mouse studies: The gene or not the gene?

(2008) Amy F. Eisener-Dorman et al.   BRAIN BEHAVIOR AND IMMUNITY

Mechanisms and functional significance of aberrant seizure-induced hippocampal neurogenesis

(2008) Jack M. Parent et al.   EPILEPSIA

IGF-1 receptor-mediated ERK/MAPK signaling couples status epilepticus to progenitor cell proliferation in the subgranular layer of the dentate gyrus

(2008) Yun-Sik Choi et al.   GLIA

Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors

(2008) Roberta Noberini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Functional Analysis of Phosphorylated Tyrosine Residues within EphA2 Receptor Tyrosine Kinase

(2008) Wei Bin Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function

(2008) L. Meikle et al.   JOURNAL OF NEUROSCIENCE

Seizure termination by acidosis depends on ASIC1a

(2008) Adam E Ziemann et al.   NATURE NEUROSCIENCE

Dynamic seizure-related changes in extracellular signal-regulated kinase activation in a mouse model of temporal lobe epilepsy

(2008) C.R. Houser et al.   NEUROSCIENCE