Adiponectin controls the apoptosis and the expression of tight junction proteins in brain endothelial cells through AdipoR1 under beta amyloid toxicity

Clinical significance of AGE-RAGE axis in colorectal cancer: associations with glyoxalase-I, adiponectin receptor expression and prognosis

(2016) Stratigoula Sakellariou et al.   BMC CANCER

Adiponectin protects palmitic acid induced endothelial inflammation and insulin resistance via regulating ROS/IKKβ pathways

(2016) Wenwen Zhao et al.   CYTOKINE

Adiponectin regulates contextual fear extinction and intrinsic excitability of dentate gyrus granule neurons through AdipoR2 receptors

(2016) D Zhang et al.   MOLECULAR PSYCHIATRY

BACE-1 is expressed in the blood–brain barrier endothelium and is upregulated in a murine model of Alzheimer’s disease

(2015) Kavi Devraj et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Striatal Blood–Brain Barrier Permeability in Parkinson'S Disease

(2015) Madison T Gray et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

(2015) Steffen E. Storck et al.   JOURNAL OF CLINICAL INVESTIGATION

The Interleukin-1 Balance During Encephalitis Is Associated With Clinical Severity, Blood-Brain Barrier Permeability, Neuroimaging Changes, and Disease Outcome

(2015) Benedict Daniel Michael et al.   JOURNAL OF INFECTIOUS DISEASES

Aβ1-42oligomer-induced leakage in anin vitroblood-brain barrier model is associated with up-regulation of RAGE and metalloproteinases, and down-regulation of tight junction scaffold proteins

(2015) Wenbin Wan et al.   JOURNAL OF NEUROCHEMISTRY

Hydrogen Sulfide Ameliorates Homocysteine-Induced Alzheimer’s Disease-Like Pathology, Blood–Brain Barrier Disruption, and Synaptic Disorder

(2015) Pradip K. Kamat et al.   MOLECULAR NEUROBIOLOGY

Resveratrol decreases the insoluble Aβ1–42 level in hippocampus and protects the integrity of the blood–brain barrier in AD rats

(2015) H.F. Zhao et al.   NEUROSCIENCE

Neurogenesis-independent antidepressant-like effects of enriched environment is dependent on adiponectin

(2015) Sarah Nicolas et al.   PSYCHONEUROENDOCRINOLOGY

Adiponectin receptor-mediated signaling ameliorates cerebral cell damage and regulates the neurogenesis of neural stem cells at high glucose concentrations: an in vivo and in vitro study

(2015) J Song et al.   Cell Death & Disease

Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer’s disease: the role, regulation and restoration of LRP1

(2015) Anita Ramanathan et al.   Frontiers in Aging Neuroscience

Amyloid-beta accumulation, neurogenesis, behavior, and the age of rats.

(2014) Russell M. Church et al.   BEHAVIORAL NEUROSCIENCE

Targeting CNS Transporters for Treatment of Neurodegenerative Diseases

(2014) Gabriele Jedlitschky et al.   CURRENT PHARMACEUTICAL DESIGN

Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice

(2014) Miguel Pappolla et al.   NEUROBIOLOGY OF DISEASE

Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin

(2014) S. Y. Yau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of Adiponectin and its Receptors in the Porcine Hypothalamus During the Oestrous Cycle

(2014) T Kaminski et al.   REPRODUCTION IN DOMESTIC ANIMALS

Aβ1–42 reduces P-glycoprotein in the blood–brain barrier through RAGE–NF-κB signaling

(2014) R Park et al.   Cell Death & Disease

Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease

(2013) Michelle A Erickson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Atorvastatin and pitavastatin reduce oxidative stress and improve IR/LDL-R signals in Alzheimer’s disease

(2013) Tomoko Kurata et al.   NEUROLOGICAL RESEARCH

Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo

(2013) Kyongman An et al.   Molecular Brain

Cerebral amyloid angiopathy impact on endothelium

(2012) Lea Tenenholz Grinberg et al.   EXPERIMENTAL GERONTOLOGY

Is RAGE still a therapeutic target for Alzheimer’s disease?

(2012) Richard J Deane   Future Medicinal Chemistry

Adiponectin is inversely associated with ratio of serum levels of AGEs to sRAGE and vascular inflammation

(2012) Nobuhiro Tahara et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Drug Transport across the Blood–Brain Barrier

(2012) William M Pardridge   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling

(2012) S.-Y. Kook et al.   JOURNAL OF NEUROSCIENCE

Low-density lipoprotein receptor-related protein 1: A physiological Aβ homeostatic mechanism with multiple therapeutic opportunities

(2012) Abhay P. Sagare et al.   PHARMACOLOGY & THERAPEUTICS

Adiponectin is Protective against Oxidative Stress Induced Cytotoxicity in Amyloid-Beta Neurotoxicity

(2012) Koon-Ho Chan et al.   PLoS One

GnRH Decreases Adiponectin Expression in Pituitary Gonadotropes via the Calcium and PKA Pathways

(2012) Jonathan Kim et al.   Reproductive Sciences

Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts

(2011) Yoko Okamoto et al.   ACTA NEUROPATHOLOGICA

Adiponectin and Its Globular Fragment Differentially Modulate the Oxidative Burst of Primary Human Phagocytes

(2011) Pia Chedid et al.   AMERICAN JOURNAL OF PATHOLOGY

Oxidative Stress and Blood–Brain Barrier Dysfunction Under Particular Consideration of Matrix Metalloproteinases

(2011) Christine Lehner et al.   ANTIOXIDANTS & REDOX SIGNALING

Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

(2011) Anna Carrano et al.   ANTIOXIDANTS & REDOX SIGNALING

The Interaction of Amyloid β and the Receptor for Advanced Glycation Endproducts Induces Matrix Metalloproteinase-2 Expression in Brain Endothelial Cells

(2011) Huan Du et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Vascular Changes in Rat Hippocampus following a High Saturated Fat and Cholesterol Diet

(2011) Linnea R Freeman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Targets for AD treatment: conflicting messages from γ-secretase inhibitors

(2011) Kumar Sambamurti et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial dysfunction: A crucial event in okadaic acid (ICV) induced memory impairment and apoptotic cell death in rat brain

(2011) Pradeep K. Kamat et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Adiponectin inhibits lymphotoxin-β receptor-mediated NF-κB signaling in human umbilical vein endothelial cells

(2010) Yizhou Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endothelial Nitric Oxide Modulates Expression and Processing of Amyloid Precursor Protein

(2010) Susan A. Austin et al.   CIRCULATION RESEARCH

Suppression of Liver Tumor Growth and Metastasis by Adiponectin in Nude Mice through Inhibition of Tumor Angiogenesis and Downregulation of Rho Kinase/IFN-Inducible Protein 10/Matrix Metalloproteinase 9 Signaling

(2010) K. Man et al.   CLINICAL CANCER RESEARCH

Blood-Brain-Barrier Models for the Investigation of Transporter- and Receptor-Mediated Amyloid-β Clearance in Alzheimers Disease

(2010) T. Pflanzner et al.   Current Alzheimer Research

Neuron-selective toxicity of tau peptide in a cell culture model of neurodegenerative tauopathy: Essential role for aggregation in neurotoxicity

(2010) Kelly Zhao et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease

(2009) Robert D. Bell et al.   ACTA NEUROPATHOLOGICA

Adiponectin protects hippocampal neurons against kainic acid-induced excitotoxicity

(2009) Byeong Tak Jeon et al.   BRAIN RESEARCH REVIEWS

Adiponectin Inhibits Lipopolysaccharide-Induced Adventitial Fibroblast Migration and Transition to Myofibroblasts via AdipoR1-AMPK-iNOS Pathway

(2009) Xiao-jun Cai et al.   MOLECULAR ENDOCRINOLOGY

Adiponectin Protects Against Angiotensin II or Tumor Necrosis Factor α–Induced Endothelial Cell Monolayer Hyperpermeability

(2008) Shi-Qiong Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Overexpression of Adiponectin Receptors Potentiates the Antiinflammatory Action of Subeffective Dose of Globular Adiponectin in Vascular Endothelial Cells

(2008) Peng Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease

(2008) Miles C. Miller et al.   BRAIN RESEARCH

The Functional Role of the Second NPXY Motif of the LRP1 β-Chain in Tissue-type Plasminogen Activator-mediated Activation ofN-Methyl-D-aspartate Receptors

(2008) Anne M. Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin impairs NADPH oxidase assembly and decreases superoxide anion production in microglia exposed to amyloid-β1-42

(2008) Juefei Zhou et al.   JOURNAL OF PINEAL RESEARCH

Antioxidant Therapy in Alzheimers Disease: Theory and Practice

(2008) Gjumrakch Aliev et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

LRP1 modulates APP trafficking along early compartments of the secretory pathway

(2008) Elaine Waldron et al.   NEUROBIOLOGY OF DISEASE