Biosynthesis of the antifungal haterumalide, oocydin A, inSerratia, and its regulation by quorum sensing, RpoS and Hfq

Bacteriophage ϕMAM1, a Viunalikevirus, Is a Broad-Host-Range, High-Efficiency Generalized Transducer That Infects Environmental and Clinical Isolates of the Enterobacterial Genera Serratia and Kluyvera

(2014) Miguel A. Matilla et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Intermediates in monensin biosynthesis: A late step in biosynthesis of the polyether ionophore monensin is crucial for the integrity of cation binding

(2014) Wolfgang Hüttel et al.   Beilstein Journal of Organic Chemistry

Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases

(2014) M. Till et al.   BIOTECHNOLOGY LETTERS

Recent advances in genome-based polyketide discovery

(2014) Eric JN Helfrich et al.   CURRENT OPINION IN BIOTECHNOLOGY

Conserved signature indels and signature proteins as novel tools for understanding microbial phylogeny and systematics: identification of molecular signatures that are specific for the phytopathogenic genera Dickeya, Pectobacterium and Brenneria

(2014) H. S. Naushad et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Viunalikeviruses are environmentally common agents of horizontal gene transfer in pathogens and biocontrol bacteria

(2014) Miguel A Matilla et al.   ISME Journal

Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes

(2014) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-seq reveals the RNA binding proteins, Hfq and RsmA, play various roles in virulence, antibiotic production and genomic flux in Serratia sp. ATCC 39006

(2013) Nabil M Wilf et al.   BMC GENOMICS

The AT2Domain of KirCI Loads Malonyl Extender Units to the ACPs of the Kirromycin PKS

(2013) Ewa Maria Musiol et al.   CHEMBIOCHEM

Global Small RNA Chaperone Hfq and Regulatory Small RNAs Are Important Virulence Regulators in Erwinia amylovora

(2013) Q. Zeng et al.   JOURNAL OF BACTERIOLOGY

Molecular Regulation of Antibiotic Biosynthesis in Streptomyces

(2013) G. Liu et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Cycling of RNAs on Hfq

(2013) E. Gerhart H. Wagner   RNA Biology

Poly Specific trans-Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases

(2012) Irina Koryakina et al.   ACS Chemical Biology

Cloning and preliminary identification of SptR, a LuxR-like regulator from Serratia plymuthica

(2012) Yunfei Duan et al.   African Journal of Microbiology Research

Discovery of the Rhizopodin Biosynthetic Gene Cluster in Stigmatella aurantiaca Sg a15 by Genome Mining

(2012) Dominik Pistorius et al.   CHEMBIOCHEM

Polyketide Proofreading by an Acyltransferase-like Enzyme

(2012) Katja Jensen et al.   CHEMISTRY & BIOLOGY

Post-transcriptional regulation on a global scale: form and function of Csr/Rsm systems

(2012) Tony Romeo et al.   ENVIRONMENTAL MICROBIOLOGY

Hfq Influences Multiple Transport Systems and Virulence in the Plant Pathogen Agrobacterium tumefaciens

(2012) I. Wilms et al.   JOURNAL OF BACTERIOLOGY

Bacterial Biosynthetic Gene Clusters Encoding the Anti-cancer Haterumalide Class of Molecules

(2012) Miguel A. Matilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acyl carrier protein structural classification and normal mode analysis

(2012) David C. Cantu et al.   PROTEIN SCIENCE

Crystallization and preliminary X-ray analysis of the bacillaene synthasetrans-acting acyltransferase PksC

(2011) Fiona Cuskin et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Biochemical Characterization of a Type III Polyketide Biosynthetic Gene Cluster from Streptomyces toxytricini

(2011) Jia Zeng et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Mupirocin: biosynthesis, special features and applications of an antibiotic from a Gram-negative bacterium

(2011) Rachel Gurney et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Structure and Mechanism of thetrans-Acting Acyltransferase from the Disorazole Synthase

(2011) Fong T. Wong et al.   BIOCHEMISTRY

Characterisation of two quorum sensing systems in the endophytic Serratia plymuthica strain G3: differential control of motility and biofilm formation according to life-style

(2011) Xiaoguang Liu et al.   BMC MICROBIOLOGY

A Late-Stage Intermediate in Salinomycin Biosynthesis Is Revealed by Specific Mutation in the Biosynthetic Gene Cluster

(2011) Marie E. Yurkovich et al.   CHEMBIOCHEM

Supramolecular Templating in Kirromycin Biosynthesis: The Acyltransferase KirCII Loads Ethylmalonyl-CoA Extender onto a Specific ACP of the trans-AT PKS

(2011) Ewa M. Musiol et al.   CHEMISTRY & BIOLOGY

The RNA chaperone, Hfq, controls two luxR-type regulators and plays a key role in pathogenesis and production of antibiotics in Serratia sp. ATCC 39006

(2011) Nabil M. Wilf et al.   ENVIRONMENTAL MICROBIOLOGY

Production of the antifungal compounds phenazine and pyrrolnitrin from Pseudomonas chlororaphis O6 is differentially regulated by glucose

(2011) J.Y. Park et al.   LETTERS IN APPLIED MICROBIOLOGY

Stringent response mutants of Pseudomonas chlororaphis PA23 exhibit enhanced antifungal activity against Sclerotinia sclerotiorum in vitro

(2011) J. Manuel et al.   MICROBIOLOGY-SGM

The stationary phase sigma factor, RpoS, regulates the production of a carbapenem antibiotic, a bioactive prodigiosin and virulence in the enterobacterial pathogen Serratia sp. ATCC 39006

(2011) N. M. Wilf et al.   MICROBIOLOGY-SGM

Hfq and its constellation of RNA

(2011) Jörg Vogel et al.   NATURE REVIEWS MICROBIOLOGY

The RpoS-Mediated General Stress Response inEscherichia coli

(2010) Aurelia Battesti et al.   Annual Review of Microbiology

Isolation and Purification of a New Kalimantacin/Batumin-Related Polyketide Antibiotic and Elucidation of Its Biosynthesis Gene Cluster

(2010) Wesley Mattheus et al.   CHEMISTRY & BIOLOGY

Quorum sensing-controlled Evr regulates a conserved cryptic pigment biosynthetic cluster and a novel phenomycin-like locus in the plant pathogen, Pectobacterium carotovorum

(2010) Neil R. Williamson et al.   ENVIRONMENTAL MICROBIOLOGY

Role of theSinorhizobium melilotiGlobal Regulator Hfq in Gene Regulation and Symbiosis

(2010) Mengsheng Gao et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Biosynthesis of polyketides by trans-AT polyketide synthases

(2010) Jörn Piel   NATURAL PRODUCT REPORTS

Positive regulation by small RNAs and the role of Hfq

(2010) T. Soper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering of new prodigiosin-based biosensors ofSerratiafor facile detection of short-chainN-acyl homoserine lactone quorum-sensing molecules

(2010) Simon Poulter et al.   Environmental Microbiology Reports

The Biosynthetic Logic of Polyketide Diversity

(2009) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Role ofBacillus subtilisBacB in the Synthesis of Bacilysin

(2009) Malligarjunan Rajavel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Total Synthesis and Cytotoxicity of Haterumalides NA and B and Their Artificial Analogues

(2009) Mitsuru Ueda et al.   JOURNAL OF ORGANIC CHEMISTRY

Quorum sensing and social networking in the microbial world

(2009) S. Atkinson et al.   Journal of the Royal Society Interface

PKS and NRPS release mechanisms

(2009) Liangcheng Du et al.   NATURAL PRODUCT REPORTS

In Vivo and In Vitro Trans-Acylation by BryP, the Putative Bryostatin Pathway Acyltransferase Derived from an Uncultured Marine Symbiont

(2008) Nicole B. Lopanik et al.   CHEMISTRY & BIOLOGY

Molecular Analysis of the Kirromycin Biosynthetic Gene Cluster Revealed β-Alanine as Precursor of the Pyridone Moiety

(2008) Tilmann Weber et al.   CHEMISTRY & BIOLOGY

Quorum-sensing effects in the antagonistic rhizosphere bacterium Serratia plymuthica HRO-C48

(2008) Henry Müller et al.   FEMS MICROBIOLOGY ECOLOGY

Stereochemical Determination and Complex Biosynthetic Assembly of Etnangien, a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum

(2008) Dirk Menche et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyunsaturated Fatty-Acid-LikeTrans-Enoyl Reductases Utilized in Polyketide Biosynthesis

(2008) Stefanie B. Bumpus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

(2008) TuAnh Nguyen et al.   NATURE BIOTECHNOLOGY

Deep Sequencing Analysis of Small Noncoding RNA and mRNA Targets of the Global Post-Transcriptional Regulator, Hfq

(2008) Alexandra Sittka et al.   PLoS Genetics

Glyceryl-S-Acyl Carrier Protein as an Intermediate in the Biosynthesis of Tetronate Antibiotics

(2007) Yuhui Sun et al.   CHEMBIOCHEM