Cycling of RNAs on Hfq

Extracting intracellular diffusive states and transition rates from single-molecule tracking data

(2013) Fredrik Persson et al.   NATURE METHODS

Multiple factors dictate target selection by Hfq-binding small RNAs

(2012) Chase L Beisel et al.   EMBO JOURNAL

An atlas of Hfq-bound transcripts reveals 3′ UTRs as a genomic reservoir of regulatory small RNAs

(2012) Yanjie Chao et al.   EMBO JOURNAL

Hexamer to Monomer Equilibrium of E. coli Hfq in Solution and Its Impact on RNA Annealing

(2012) Subrata Panja et al.   JOURNAL OF MOLECULAR BIOLOGY

The Seed Region of a Small RNA Drives the Controlled Destruction of the Target mRNA by the Endoribonuclease RNase E

(2012) Katarzyna J. Bandyra et al.   MOLECULAR CELL

A mixed double negative feedback loop between the sRNA MicF and the global regulator Lrp

(2012) Erik Holmqvist et al.   MOLECULAR MICROBIOLOGY

The low-resolution solution structure of Vibrio cholerae Hfq in complex with Qrr1 sRNA

(2012) Helen A. Vincent et al.   NUCLEIC ACIDS RESEARCH

Structural mechanism of Staphylococcus aureus Hfq binding to an RNA A-tract

(2012) Nicola Horstmann et al.   NUCLEIC ACIDS RESEARCH

Hfq proximity and orientation controls RNA annealing

(2012) Subrata Panja et al.   NUCLEIC ACIDS RESEARCH

Structural flexibility of RNA as molecular basis for Hfq chaperone function

(2012) Euripedes de Almeida Ribeiro et al.   NUCLEIC ACIDS RESEARCH

Study of E. coli Hfq’s RNA annealing acceleration and duplex destabilization activities using substrates with different GC-contents

(2012) Martina Doetsch et al.   NUCLEIC ACIDS RESEARCH

Requirement of upstream Hfq-binding (ARN)x elements in glmS and the Hfq C-terminal region for GlmS upregulation by sRNAs GlmZ and GlmY†

(2012) Nilshad N. Salim et al.   NUCLEIC ACIDS RESEARCH

Structural and Biochemical Studies on ATP Binding and Hydrolysis by the Escherichia coli RNA Chaperone Hfq

(2012) Hermann Hämmerle et al.   PLoS One

Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition

(2012) E. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The functional Hfq-binding module of bacterial sRNAs consists of a double or single hairpin preceded by a U-rich sequence and followed by a 3' poly(U) tail

(2012) H. Ishikawa et al.   RNA

Despite Similar Binding to the Hfq Protein Regulatory RNAs Widely Differ in Their Competition Performance

(2011) Mikołaj Olejniczak   BIOCHEMISTRY

The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators

(2011) Makhlouf Rabhi et al.   EMBO JOURNAL

Cooperation of Escherichia coli Hfq hexamers in DsrA binding

(2011) W. Wang et al.   GENES & DEVELOPMENT

Regulation by Small RNAs in Bacteria: Expanding Frontiers

(2011) Gisela Storz et al.   MOLECULAR CELL

Competition among Hfq-binding small RNAs in Escherichia coli

(2011) Kyung Moon et al.   MOLECULAR MICROBIOLOGY

Contribution of Hfq to photooxidative stress resistance and global regulation in Rhodobacter sphaeroides

(2011) Bork A. Berghoff et al.   MOLECULAR MICROBIOLOGY

Hfq and its constellation of RNA

(2011) Jörg Vogel et al.   NATURE REVIEWS MICROBIOLOGY

Dynamic competition of DsrA and rpoS fragments for the proximal binding site of Hfq as a means for efficient annealing

(2011) Wonseok Hwang et al.   NUCLEIC ACIDS RESEARCH

A highly conserved protein of unknown function in Sinorhizobium meliloti affects sRNA regulation similar to Hfq

(2011) Shree P. Pandey et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq

(2011) Tatsuhiko Someya et al.   NUCLEIC ACIDS RESEARCH

Rapid binding and release of Hfq from ternary complexes during RNA annealing

(2011) Julia F. Hopkins et al.   NUCLEIC ACIDS RESEARCH

Quantifying the sequence-function relation in gene silencing by bacterial small RNAs

(2011) Y. Hao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PolyU tail of rho-independent terminator of bacterial small RNAs is essential for Hfq action

(2011) Hironori Otaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for RNA 3′-end recognition by Hfq

(2011) Evelyn Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The stoichiometry of the Escherichia coli Hfq protein bound to RNA

(2011) T. B. Updegrove et al.   RNA

Role of polynucleotide phosphorylase in sRNA function in Escherichia coli

(2011) N. De Lay et al.   RNA

The role of Hfq in bacterial pathogens

(2010) Yanjie Chao et al.   CURRENT OPINION IN MICROBIOLOGY

Two antisense RNAs target the transcriptional regulator CsgD to inhibit curli synthesis

(2010) Erik Holmqvist et al.   EMBO JOURNAL

RNAs actively cycle on the Sm-like protein Hfq

(2010) A. Fender et al.   GENES & DEVELOPMENT

C-Terminally Truncated Derivatives of Escherichia coli Hfq Are Proficient in Riboregulation

(2010) Anders Steno Olsen et al.   JOURNAL OF MOLECULAR BIOLOGY

Hfq binding at RhlB-recognition region of RNase E is crucial for the rapid degradation of target mRNAs mediated by sRNAs in Escherichia coli

(2010) Yoshiki Ikeda et al.   MOLECULAR MICROBIOLOGY

Spatial organization of the flow of genetic information in bacteria

(2010) Paula Montero Llopis et al.   NATURE

Genomic SELEX for Hfq-binding RNAs identifies genomic aptamers predominantly in antisense transcripts

(2010) C. Lorenz et al.   NUCLEIC ACIDS RESEARCH

An Upstream Hfq Binding Site in the fhlA mRNA Leader Region Facilitates the OxyS-fhlA Interaction

(2010) Nilshad N. Salim et al.   PLoS One

Disruption of small RNA signaling caused by competition for Hfq

(2010) R. Hussein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positive regulation by small RNAs and the role of Hfq

(2010) T. Soper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deep sequencing of Salmonella RNA associated with heterologous Hfq proteins in vivo reveals small RNAs as a major target class and identifies RNA processing phenotypes

(2010) Alexandra Sittka et al.   RNA Biology

Regulatory RNAs in Bacteria

(2009) Lauren S. Waters et al.   CELL

Specific and pleiotropic patterns of mRNA regulation by ArcZ, a conserved, Hfq-dependent small RNA

(2009) Kai Papenfort et al.   MOLECULAR MICROBIOLOGY

Effect of salt and RNA structure on annealing and strand displacement by Hfq

(2009) J. F. Hopkins et al.   NUCLEIC ACIDS RESEARCH

Cellular Electron Microscopy Imaging Reveals the Localization of the Hfq Protein Close to the Bacterial Membrane

(2009) Elia Diestra et al.   PLoS One

Structure of Escherichia coli Hfq bound to polyriboadenylate RNA

(2009) T. M. Link et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of small RNAs in Pseudomonas aeruginosa by RNomics and structure-based bioinformatic tools

(2008) E. Sonnleitner et al.   MICROBIOLOGY-SGM

A quantitative comparison of sRNA-based and protein-based gene regulation

(2008) Pankaj Mehta et al.   Molecular Systems Biology

The rpoS mRNA leader recruits Hfq to facilitate annealing with DsrA sRNA

(2008) T. J. Soper et al.   RNA

Deep Sequencing Analysis of Small Noncoding RNA and mRNA Targets of the Global Post-Transcriptional Regulator, Hfq

(2008) Alexandra Sittka et al.   PLoS Genetics