Bacterial Biosynthetic Gene Clusters Encoding the Anti-cancer Haterumalide Class of Molecules

Discovery of the Rhizopodin Biosynthetic Gene Cluster in Stigmatella aurantiaca Sg a15 by Genome Mining

(2012) Dominik Pistorius et al.   CHEMBIOCHEM

Polyketide Proofreading by an Acyltransferase-like Enzyme

(2012) Katja Jensen et al.   CHEMISTRY & BIOLOGY

Emerging fungal threats to animal, plant and ecosystem health

(2012) Matthew C. Fisher et al.   NATURE

Mupirocin: biosynthesis, special features and applications of an antibiotic from a Gram-negative bacterium

(2011) Rachel Gurney et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An Additional Dehydratase-Like Activity is Required for Lankacidin Antibiotic Biosynthesis

(2011) Jeroen S. Dickschat  et al.   CHEMBIOCHEM

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

The development, regulation and use of biopesticides for integrated pest management

(2011) D. Chandler et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium

(2011) J. P. Ramsay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome Mining Reveals trans-AT Polyketide Synthase Directed Antibiotic Biosynthesis in the Bacterial Phylum Bacteroidetes

(2010) Roberta Teta  et al.   CHEMBIOCHEM

Analysis of the Sorangicin Gene Cluster Reinforces the Utility of a Combined Phylogenetic/Retrobiosynthetic Analysis for Deciphering Natural Product Assembly by trans-AT PKS

(2010) Herbert Irschik  et al.   CHEMBIOCHEM

Isolation and Purification of a New Kalimantacin/Batumin-Related Polyketide Antibiotic and Elucidation of Its Biosynthesis Gene Cluster

(2010) Wesley Mattheus et al.   CHEMISTRY & BIOLOGY

Oxazolomycin Biosynthesis inStreptomyces albusJA3453 Featuring an “Acyltransferase-less” Type I Polyketide Synthase That Incorporates Two Distinct Extender Units

(2010) Chunhua Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chloramphenicol Biosynthesis: The Structure of CmlS, a Flavin-Dependent Halogenase Showing a Covalent Flavin–Aspartate Bond

(2010) Kateryna Podzelinska et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of Tiacumicin B Biosynthetic Gene Cluster Affording Diversified Tiacumicin Analogues and Revealing a Tailoring Dihalogenase

(2010) Yi Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biosynthesis of polyketides by trans-AT polyketide synthases

(2010) Jörn Piel   NATURAL PRODUCT REPORTS

CDD: a Conserved Domain Database for the functional annotation of proteins

(2010) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes

(2010) L. C. Foulston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Biosynthetic Logic of Polyketide Diversity

(2009) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Plant-Growth-Promoting Rhizobacteria

(2009) Ben Lugtenberg et al.   Annual Review of Microbiology

Biohalogenation: Nature’s Way to Synthesize Halogenated Metabolites†

(2009) Claudia Wagner et al.   JOURNAL OF NATURAL PRODUCTS

Total Synthesis and Cytotoxicity of Haterumalides NA and B and Their Artificial Analogues

(2009) Mitsuru Ueda et al.   JOURNAL OF ORGANIC CHEMISTRY

Genes for the Biosynthesis of the Fungal Polyketides Hypothemycin from Hypomyces subiculosus and Radicicol from Pochonia chlamydosporia

(2008) C. D. Reeves et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

In Vivo and In Vitro Trans-Acylation by BryP, the Putative Bryostatin Pathway Acyltransferase Derived from an Uncultured Marine Symbiont

(2008) Nicole B. Lopanik et al.   CHEMISTRY & BIOLOGY

Halogenation Strategies In Natural Product Biosynthesis

(2008) Christopher S. Neumann et al.   CHEMISTRY & BIOLOGY

Molecular Analysis of the Kirromycin Biosynthetic Gene Cluster Revealed β-Alanine as Precursor of the Pyridone Moiety

(2008) Tilmann Weber et al.   CHEMISTRY & BIOLOGY

Crystal Structure of the Erythromycin Polyketide Synthase Dehydratase

(2008) Adrian Keatinge-Clay   JOURNAL OF MOLECULAR BIOLOGY

Stereochemical Determination and Complex Biosynthetic Assembly of Etnangien, a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum

(2008) Dirk Menche et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyunsaturated Fatty-Acid-LikeTrans-Enoyl Reductases Utilized in Polyketide Biosynthesis

(2008) Stefanie B. Bumpus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Halogenase Genes in Nonribosomal Peptide Synthetase Gene Clusters of Microcystis (Cyanobacteria): Sporadic Distribution and Evolution

(2008) S. Cadel-Six et al.   MOLECULAR BIOLOGY AND EVOLUTION

Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways

(2008) Elizabeth S. Sattely et al.   NATURAL PRODUCT REPORTS

The rhizosphere: a playground and battlefield for soilborne pathogens and beneficial microorganisms

(2008) Jos M. Raaijmakers et al.   PLANT AND SOIL

Glyceryl-S-Acyl Carrier Protein as an Intermediate in the Biosynthesis of Tetronate Antibiotics

(2007) Yuhui Sun et al.   CHEMBIOCHEM

Phosphate availability regulates biosynthesis of two antibiotics, prodigiosin and carbapenem, in Serratia via both quorum-sensing-dependent and -independent pathways

(2003) Holly Slater et al.   MOLECULAR MICROBIOLOGY