PPR-SMR protein SOT1 has RNA endonuclease activity

Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering

(2016) Addison V. Wright et al.   CELL

Modifying the Mitochondrial Genome

(2016) Alexander N. Patananan et al.   Cell Metabolism

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

(2016) Alexandra East-Seletsky et al.   NATURE

The PPR-SMR protein PPR53 enhances the stability and translation of specific chloroplast RNAs in maize

(2016) Reimo Zoschke et al.   PLANT JOURNAL

SOT1, a pentatricopeptide repeat protein with a small MutS-related domain, is required for correct processing of plastid 23S-4.5S rRNA precursors in Arabidopsis thaliana

(2016) Wenjuan Wu et al.   PLANT JOURNAL

Programmable RNA-binding protein composed of repeats of a single modular unit

(2016) Katarzyna P. Adamala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

(2016) Omar O. Abudayyeh et al.   SCIENCE

Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins

(2016) Cuicui Shen et al.   Nature Communications

Engineering Plastid Genomes: Methods, Tools, and Applications in Basic Research and Biotechnology

(2015) Ralph Bock   Annual Review of Plant Biology

The nuclease activities of both the Smr domain and an additional LDLK motif are required for an efficient anti-recombination function ofHelicobacter pylori MutS2

(2015) Prashant P. Damke et al.   MOLECULAR MICROBIOLOGY

Specific RNA Recognition by Designer Pentatricopeptide Repeat Protein

(2015) Cuicui Shen et al.   Molecular Plant

The solution structure of the pentatricopeptide repeat protein PPR10 upon binding atpH RNA

(2015) Benjamin S. Gully et al.   NUCLEIC ACIDS RESEARCH

Arabidopsis Chloroplast Mini-Ribonuclease III Participates in rRNA Maturation and Intron Recycling

(2015) Amber M. Hotto et al.   PLANT CELL

Predictable Alteration of Sequence Recognition by RNA Editing Factors from Arabidopsis

(2015) Peter Kindgren et al.   PLANT CELL

The Conserved Endoribonuclease YbeY Is Required for Chloroplast Ribosomal RNA Processing in Arabidopsis

(2015) Jinwen Liu et al.   PLANT PHYSIOLOGY

The design and structural characterization of a synthetic pentatricopeptide repeat protein

(2015) Benjamin S. Gully et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Bidirectional Regulation of mRNA Translation in Mammalian Cells by Using PUF Domains

(2014) Jicong Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pentatricopeptide Repeat Proteins in Plants

(2014) Alice Barkan et al.   Annual Review of Plant Biology

Structural and functional studies of MutS2 from Deinococcus radiodurans

(2014) Hui Zhang et al.   DNA REPAIR

Programmable RNA recognition and cleavage by CRISPR/Cas9

(2014) Mitchell R. O’Connell et al.   NATURE

A protein-RNA specificity code enables targeted activation of an endogenous human transcript

(2014) Zachary T Campbell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Expanding the RNA-recognition code of PUF proteins

(2014) Traci M Tanaka Hall   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quantitative analysis of motifs contributing to the interaction between PLS-subfamily members and their target RNA sequences in plastid RNA editing

(2014) Kenji Okuda et al.   PLANT JOURNAL

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

An artificial PPR scaffold for programmable RNA recognition

(2014) Sandrine Coquille et al.   Nature Communications

Engineering RNA-binding proteins for biology

(2013) Yu Chen et al.   FEBS Journal

Transformation of the mitochondrial genome

(2013) Véronique Larosa et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Treatment of Type 1 Myotonic Dystrophy by Engineering Site-specific RNA Endonucleases that Target (CUG) n Repeats

(2013) Wenjing Zhang et al.   MOLECULAR THERAPY

Structural basis for the modular recognition of single-stranded RNA by PPR proteins

(2013) Ping Yin et al.   NATURE

Structural basis for RNA recognition by a dimeric PPR-protein complex

(2013) Jiyuan Ke et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Elucidation of the RNA Recognition Code for Pentatricopeptide Repeat Proteins Involved in Organelle RNA Editing in Plants

(2013) Yusuke Yagi et al.   PLoS One

Improved Computational Target Site Prediction for Pentatricopeptide Repeat RNA Editing Factors

(2013) Mizuki Takenaka et al.   PLoS One

PPR-SMRs

(2013) Sheng Liu et al.   RNA Biology

Mutation of the pentatricopeptide repeat-SMR protein SVR7 impairs accumulation and translation of chloroplast ATP synthase subunits in Arabidopsis thaliana

(2012) Reimo Zoschke et al.   JOURNAL OF PLANT RESEARCH

The pentatricopeptide repeat-SMR protein ATP4 promotes translation of the chloroplastatpB/EmRNA

(2012) Reimo Zoschke et al.   PLANT JOURNAL

Engineering RNA endonucleases with customized sequence specificities

(2012) Rajarshi Choudhury et al.   Nature Communications

A Combinatorial Amino Acid Code for RNA Recognition by Pentatricopeptide Repeat Proteins

(2012) Alice Barkan et al.   PLoS Genetics

Ubiquitination of mRNA cycling sequence binding protein fromLeishmania donovani(LdCSBP) modulates the RNA endonuclease activity of its Smr domain

(2011) Dipankar Bhandari et al.   FEBS LETTERS

Crystal structure of YdaL, a stand-alone small MutS-related protein from Escherichia coli

(2011) Wen-Jun Gui et al.   JOURNAL OF STRUCTURAL BIOLOGY

A universal code for RNA recognition by PUF proteins

(2011) Aleksandra Filipovska et al.   Nature Chemical Biology

Targeted translational regulation using the PUF protein family scaffold

(2011) A. Cooke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Arabidopsis Pentatricopeptide Repeat Protein, SUPPRESSOR OF VARIEGATION7, Is Required for FtsH-Mediated Chloroplast Biogenesis

(2010) X. Liu et al.   PLANT PHYSIOLOGY

Mechanism of RNA stabilization and translational activation by a pentatricopeptide repeat protein

(2010) J. Prikryl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PIN-domain ribonucleases and the prokaryotic VapBC toxin-antitoxin array

(2010) V. L. Arcus et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Ribosomal protein L3 bound to 23S precursor rRNA stimulates its maturation by Mini-III ribonuclease

(2009) Yulia Redko et al.   MOLECULAR MICROBIOLOGY

Engineering splicing factors with designed specificities

(2009) Yang Wang et al.   NATURE METHODS

Crystal Structure of MutS2 Endonuclease Domain and the Mechanism of Homologous Recombination Suppression

(2008) Kenji Fukui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution Structure and Characterization of the DNA-Binding Activity of the B3BP–Smr Domain

(2008) Tammo Diercks et al.   JOURNAL OF MOLECULAR BIOLOGY

Mini-III, an unusual member of the RNase III family of enzymes, catalyses 23S ribosomal RNA maturation in B. subtilis

(2008) Yulia Redko et al.   MOLECULAR MICROBIOLOGY