The New Biology and Pharmacology of Glucagon

Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes

(2016) Nicolai J. Wewer Albrechtsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-Dependent Insulinotropic Polypeptide Receptors

(2016) Ying Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

(2016) Brian Finan et al.   CELL

Unimolecular Polypharmacy for Treatment of Diabetes and Obesity

(2016) Matthias H. Tschöp et al.   Cell Metabolism

Clinical Trials, Triumphs, and Tribulations of Glucagon Receptor Antagonists

(2016) Mackenzie J. Pearson et al.   DIABETES CARE

Effects of multiple ascending doses of the glucagon receptor antagonist PF-06291874 in patients with type 2 diabetes mellitus

(2016) D. J. Kazierad et al.   DIABETES OBESITY & METABOLISM

Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates

(2016) S. J. Henderson et al.   DIABETES OBESITY & METABOLISM

L-arginine promotes gut hormone release and reduces food intake in rodents

(2016) A. Alamshah et al.   DIABETES OBESITY & METABOLISM

Glucagon is the key factor in the development of diabetes

(2016) Young H. Lee et al.   DIABETOLOGIA

Effects of glucagon-like peptide-1 on glucagon secretion in patients with non-alcoholic fatty liver disease

(2016) Anders E. Junker et al.   JOURNAL OF HEPATOLOGY

Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism

(2016) Sarah A. Stanley et al.   NATURE

Amylin-mediated control of glycemia, energy balance, and cognition

(2016) Elizabeth G. Mietlicki-Baase   PHYSIOLOGY & BEHAVIOR

Reappraisal of GIP Pharmacology for Metabolic Diseases

(2016) Brian Finan et al.   TRENDS IN MOLECULAR MEDICINE

Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist

(2016) Nicolas Damond et al.   eLife

Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival

(2016) Ursula H. Neumann et al.   Molecular Metabolism

Essential role of UCP1 modulating the central effects of thyroid hormones on energy balance

(2016) Mayte Alvarez-Crespo et al.   Molecular Metabolism

The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1

(2015) Astrid Plamboeck et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Glucagon – the new ‘insulin’ in the pathophysiology of diabetes

(2015) Leon S. Farhy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Evaluation of Efficacy and Safety of the Glucagon Receptor Antagonist LY2409021 in Patients With Type 2 Diabetes: 12- and 24-Week Phase 2 Studies

(2015) Christof M. Kazda et al.   DIABETES CARE

Short-term administration of the glucagon receptor antagonist LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes

(2015) R. P. Kelly et al.   DIABETES OBESITY & METABOLISM

Efficacy and safety of liraglutide monotherapy compared with metformin in Japanese overweight/obese patients with type 2 diabetes

(2015) Kumiko Tanaka et al.   ENDOCRINE JOURNAL

Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys

(2015) Haruka Okamoto et al.   ENDOCRINOLOGY

Effect of Short-term Intensive Insulin Therapy on Post-challenge Hyperglucagonemia in Early Type 2 Diabetes

(2015) Caroline K. Kramer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucagon receptor antagonism induces increased cholesterol absorption

(2015) Hong-Ping Guan et al.   JOURNAL OF LIPID RESEARCH

Emerging opportunities for the treatment of metabolic diseases: Glucagon-like peptide-1 based multi-agonists

(2015) Brian Finan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Islet α cells and glucagon—critical regulators of energy homeostasis

(2015) Jonathan E. Campbell et al.   Nature Reviews Endocrinology

Physiology of Proglucagon Peptides: Role of Glucagon and GLP-1 in Health and Disease

(2015) Darleen A. Sandoval et al.   PHYSIOLOGICAL REVIEWS

Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance

(2015) Mar Quiñones et al.   Molecular Metabolism

Degradation and Stabilization of Peptide Hormones in Human Blood Specimens

(2015) Jizu Yi et al.   PLoS One

Hypothalamic effects of thyroid hormones on metabolism

(2014) Noelia Martínez-Sánchez et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Hypoglycemia-Activated GLUT2 Neurons of the Nucleus Tractus Solitarius Stimulate Vagal Activity and Glucagon Secretion

(2014) Christophe M. Lamy et al.   Cell Metabolism

Glucagon Regulates Hepatic Kisspeptin to Impair Insulin Secretion

(2014) Woo-Jin Song et al.   Cell Metabolism

Coinfusion of Low-Dose GLP-1 and Glucagon in Man Results in a Reduction in Food Intake

(2014) Jaimini Cegla et al.   DIABETES

Evidence for inhibitory autocrine effects of proinsulin C-peptide on pancreaticβ-cell function and insulin secretion

(2014) A. M. McKillop et al.   DIABETES OBESITY & METABOLISM

Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): implications for GLP-1 measurements in clinical studies

(2014) M. J. Bak et al.   DIABETES OBESITY & METABOLISM

Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

(2014) Nicolai J. Wewer Albrechtsen et al.   DIABETOLOGIA

GLP-1–oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice

(2014) Robert W. Schwenk et al.   DIABETOLOGIA

Glucagon Is Essential for Adaptive Thermogenesis in Brown Adipose Tissue

(2014) Keita Kinoshita et al.   ENDOCRINOLOGY

Evolution of receptors for peptides similar to glucagon

(2014) David M. Irwin   GENERAL AND COMPARATIVE ENDOCRINOLOGY

First proof of pharmacology in humans of a novel glucagon receptor antisense drug

(2014) Marloes G. J. van Dongen et al.   JOURNAL OF CLINICAL PHARMACOLOGY

MOLECULAR EVOLUTION OF GPCRS: Somatostatin/urotensin II receptors

(2014) Hervé Tostivint et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

(2014) Brian Finan et al.   NATURE MEDICINE

Glucagon Stimulates Hepatic FGF21 Secretion through a PKA- and EPAC-Dependent Posttranscriptional Mechanism

(2014) Holly A. Cyphert et al.   PLoS One

Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action

(2013) Jonathan E. Campbell et al.   Cell Metabolism

GLP-1R Agonism Enhances Adjustable Gastric Banding in Diet-Induced Obese Rats

(2013) Kirk M. Habegger et al.   DIABETES

Amelioration of Hypoglycemia Via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats

(2013) J. T. Y. Yue et al.   DIABETES

GLP-1/Glucagon Coagonism Restores Leptin Responsiveness in Obese Mice Chronically Maintained on an Obesogenic Diet

(2013) C. Clemmensen et al.   DIABETES

GLP-1R Responsiveness Predicts Individual Gastric Bypass Efficacy on Glucose Tolerance in Rats

(2013) K. M. Habegger et al.   DIABETES

Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

(2013) K. M. Habegger et al.   DIABETES

Vertical Sleeve Gastrectomy Is Effective in Two Genetic Mouse Models of Glucagon-Like Peptide 1 Receptor Deficiency

(2013) H. E. Wilson-Perez et al.   DIABETES

Orall-Arginine Stimulates GLP-1 Secretion to Improve Glucose Tolerance in Male Mice

(2013) Christoffer Clemmensen et al.   ENDOCRINOLOGY

Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes

(2013) Mikkel B. Christensen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cooperation between brain and islet in glucose homeostasis and diabetes

(2013) Michael W. Schwartz et al.   NATURE

Hypothalamic glucagon signaling inhibits hepatic glucose production

(2013) Patricia I Mighiu et al.   NATURE MEDICINE

Pramlintide Improved Measures of Glycemic Control and Body Weight in Patients With Type I Diabetes Mellitus Undergoing Continuous Subcutaneous Insulin Infusion Therapy

(2013) Kathrin Herrmann et al.   POSTGRADUATE MEDICINE

Energy balance regulation by thyroid hormones at central level

(2013) Miguel López et al.   TRENDS IN MOLECULAR MEDICINE

Mechanisms underlying current and future anti-obesity drugs

(2013) Roger A.H. Adan   TRENDS IN NEUROSCIENCES

Hypothalamic glucagon signals through the KATP channels to regulate glucose production

(2013) Mona A. Abraham et al.   Molecular Metabolism

SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells

(2012) Balrik Kailey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Return of Rainbow Diet Pills

(2012) Pieter A. Cohen et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

The l-α-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in l-arginine-induced insulin release

(2012) Sanela Smajilovic et al.   AMINO ACIDS

Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents

(2012) Jonathan W. Day et al.   BIOPOLYMERS

The mechanism underlying the central glucagon-induced hyperglycemia and anorexia in chicks

(2012) Kazuhisa Honda et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

In Situ Electrophysiological Examination of Pancreatic   Cells in the Streptozotocin-Induced Diabetes Model, Revealing the Cellular Basis of Glucagon Hypersecretion

(2012) Y.-C. Huang et al.   DIABETES

Coadministration of Glucagon-Like Peptide-1 During Glucagon Infusion in Humans Results in Increased Energy Expenditure and Amelioration of Hyperglycemia

(2012) T. M. Tan et al.   DIABETES

Liver-Specific Disruption of the Murine Glucagon Receptor Produces  -Cell Hyperplasia: Evidence for a Circulating  -Cell Growth Factor

(2012) C. Longuet et al.   DIABETES

Effect of Pramlintide on Prandial Glycemic Excursions During Closed-Loop Control in Adolescents and Young Adults With Type 1 Diabetes

(2012) S. A. Weinzimer et al.   DIABETES CARE

Glucagon increases circulating fibroblast growth factor 21 independently of endogenous insulin levels: a novel mechanism of glucagon-stimulated lipolysis?

(2012) A. M. Arafat et al.   DIABETOLOGIA

GPRC6A Mediates the Effects ofl-Arginine on Insulin Secretion in Mouse Pancreatic Islets

(2012) Min Pi et al.   ENDOCRINOLOGY

Activation of the Farnesoid X Receptor Induces Hepatic Expression and Secretion of Fibroblast Growth Factor 21

(2012) Holly A. Cyphert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

(2012) Roger H. Unger et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy on Glucose and Gut Hormones: a Prospective Randomised Trial

(2012) José Manuel Ramón et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Discovery of a Novel Glucagon Receptor Antagonist N-[(4-{(1S)-1-[3-(3, 5-Dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the Treatment of Type II Diabetes

(2012) Yusheng Xiong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21

(2012) Timo D. Müller et al.   JOURNAL OF PEPTIDE SCIENCE

The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine

(2012) Oliver J. Mace et al.   JOURNAL OF PHYSIOLOGY-LONDON

Targeted estrogen delivery reverses the metabolic syndrome

(2012) Brian Finan et al.   NATURE MEDICINE

The Glucagon Receptor Is Involved in Mediating the Body Weight-Lowering Effects of Oxyntomodulin

(2012) Jennifer R. Kosinski et al.   Obesity

Targeting the glucagon receptor family for diabetes and obesity therapy

(2012) Young Min Cho et al.   PHARMACOLOGY & THERAPEUTICS

Anti-Diabetic Efficacy and Impact on Amino Acid Metabolism of GRA1, a Novel Small-Molecule Glucagon Receptor Antagonist

(2012) James Mu et al.   PLoS One

Human Monoclonal Antibodies against Glucagon Receptor Improve Glucose Homeostasis by Suppression of Hepatic Glucose Output in Diet-Induced Obese Mice

(2012) Wook-Dong Kim et al.   PLoS One

The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

(2011) Asger Lund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction

(2011) Yong Xu et al.   Cell Metabolism

Glucagon as a Critical Factor in the Pathology of Diabetes

(2011) D. S. Edgerton et al.   DIABETES

Somatostatin Receptor Type 2 Antagonism Improves Glucagon and Corticosterone Counterregulatory Responses to Hypoglycemia in Streptozotocin-Induced Diabetic Rats

(2011) J. T. Y. Yue et al.   DIABETES

Glucose-Dependent Insulinotropic Polypeptide: A Bifunctional Glucose-Dependent Regulator of Glucagon and Insulin Secretion in Humans

(2011) M. Christensen et al.   DIABETES

Regulation of glucagon secretion by incretins

(2011) J. J. Holst et al.   DIABETES OBESITY & METABOLISM

Glucagon gene expression in the endocrine pancreas: the role of the transcription factor Pax6 in α-cell differentiation, glucagon biosynthesis and secretion

(2011) Y. Gosmain et al.   DIABETES OBESITY & METABOLISM

Chronic treatment with a glucagon receptor antagonist lowers glucose and moderately raises circulating glucagon and glucagon-like peptide 1 without severe alpha cell hypertrophy in diet-induced obese mice

(2011) J. Mu et al.   DIABETOLOGIA

Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca2+and cAMP

(2011) Gwen Tolhurst et al.   ENDOCRINOLOGY

Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis

(2011) Safina Ali et al.   JOURNAL OF CLINICAL INVESTIGATION

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

(2011) Judith Y. Altarejos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Impact of Laparoscopic Sleeve Gastrectomy and Laparoscopic Gastric Bypass on HbA1c Blood Level and Pharmacological Treatment of Type 2 Diabetes Mellitus in Severe or Morbidly Obese Patients. Results of a Multicenter Prospective Study at 1 Year

(2011) David Nocca et al.   OBESITY SURGERY

Glucose-dependent docking and SNARE protein-mediated exocytosis in mouse pancreatic alpha-cell

(2011) Sofia A. Andersson et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Laparoscopic sleeve gastrectomy and laparoscopic gastric bypass are equally effective for reduction of cardiovascular risk in severely obese patients at one year of follow-up

(2011) David Benaiges et al.   Surgery for Obesity and Related Diseases

A role for islet somatostatin in mediating sympathetic regulation of glucagon secretion

(2011) Astrid C. Hauge-Evans et al.   Islets

Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor

(2010) Wei Gu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Phosphorylation of the CREB-specific coactivator TORC2 at Ser307 regulates its intracellular localization in COS-7 cells and in the mouse liver

(2010) Tatsuya Uebi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucagon and lipid interactions in the regulation of hepatic AMPK signaling and expression of PPARα and FGF21 transcripts in vivo

(2010) Eric D. Berglund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis

(2010) Sabine D. Jordan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Glucagonostatic and Insulinotropic Effects of Glucagon-Like Peptide 1 Contribute Equally to Its Glucose-Lowering Action

(2010) K. J. Hare et al.   DIABETES

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

(2010) Miguel López et al.   NATURE MEDICINE

A tale of two hormones

(2010) Jeffrey M Friedman   NATURE MEDICINE

The metabolic actions of glucagon revisited

(2010) Kirk M. Habegger et al.   Nature Reviews Endocrinology

GIP and GLP-1, the two incretin hormones: Similarities and differences

(2010) Yutaka Seino et al.   Journal of Diabetes Investigation

Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes

(2009) Maziyar Saberi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exogenous Glucose-Dependent Insulinotropic Polypeptide Worsens Post prandial Hyperglycemia in T ype 2 Diabetes

(2009) C. W. Chia et al.   DIABETES

Glucagon-Like Peptide 1/Glucagon Receptor Dual Agonism Reverses Obesity in Mice

(2009) A. Pocai et al.   DIABETES

Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells

(2009) M. Braun et al.   DIABETOLOGIA

Fibroblast Growth Factor 21-Deficient Mice Demonstrate Impaired Adaptation to Ketosis

(2009) Michael K. Badman et al.   ENDOCRINOLOGY

Effect of Glucagon on Glucose Output from Bivascularly Perfused Rat Liver

(2009) T. Ikeda et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

The role of amylin in the physiology of glycemic control

(2009) W. A. Scherbaum   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Endocrine Cell Clustering During Human Pancreas Development

(2009) Jongmin Jeon et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Fully Human Monoclonal Antibodies Antagonizing the Glucagon Receptor Improve Glucose Homeostasis in Mice and Monkeys

(2009) H. Yan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Differential expression of glucagon and glucagon-like peptide 1 receptors in mouse pancreatic alpha and beta cells in two models of alpha cell hyperplasia

(2009) Mamdouh H. Kedees et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A new glucagon and GLP-1 co-agonist eliminates obesity in rodents

(2009) Jonathan W Day et al.   Nature Chemical Biology

Thyroid hormone mimetics: potential applications in atherosclerosis, obesity and type 2 diabetes

(2009) John D. Baxter et al.   NATURE REVIEWS DRUG DISCOVERY

Interaction of Leptin and Amylin in the Long-term Maintenance of Weight Loss in Diet-induced Obese Rats

(2009) James L. Trevaskis et al.   Obesity

Pax6 and Pdx1 are required for production of glucose-dependent insulinotropic polypeptide in proglucagon-expressing L cells

(2008) Yukihiro Fujita et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cross-talk between estrogen and leptin signaling in the hypothalamus

(2008) Qian Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetes

(2008) Safina Ali et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Characterization of voltage operated R-type Ca2+ channels in modulating somatostatin receptor subtype 2- and 3-dependent inhibition of insulin secretion from INS-1 cells

(2008) Stefan Mergler et al.   CELLULAR SIGNALLING

Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts

(2008) A. Wojtusciszyn et al.   DIABETOLOGIA

Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

(2008) J. de Heer et al.   DIABETOLOGIA

Cross Talk between the Insulin and Wnt Signaling Pathways: Evidence from Intestinal Endocrine L Cells

(2008) Fenghua Yi et al.   ENDOCRINOLOGY

Fibroblast Growth Factor 21 Corrects Obesity in Mice

(2008) Tamer Coskun et al.   ENDOCRINOLOGY

Amylin-Mediated Restoration of Leptin Responsiveness in Diet-Induced Obesity: Magnitude and Mechanisms

(2008) James L. Trevaskis et al.   ENDOCRINOLOGY

N-Type Ca2+-Channels in Murine Pancreatic β-Cells Are Inhibited by an Exclusive Coupling with Somatostatin Receptor Subtype 1

(2008) Paul A. Smith   ENDOCRINOLOGY

Mechanisms underlying proglucagon gene expression

(2008) Tianru Jin   JOURNAL OF ENDOCRINOLOGY

Physiology of the pancreatic α-cell and glucagon secretion: role in glucose homeostasis and diabetes

(2008) Ivan Quesada et al.   JOURNAL OF ENDOCRINOLOGY

Novel aspects of the molecular mechanisms controlling insulin secretion

(2008) Lena Eliasson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies

(2008) J. D. Roth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel GIP receptor splice variant influences GIP sensitivity of pancreatic β-cells in obese mice

(2007) Norio Harada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM