Glucagon increases circulating fibroblast growth factor 21 independently of endogenous insulin levels: a novel mechanism of glucagon-stimulated lipolysis?
Published 2012 View Full Article
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Title
Glucagon increases circulating fibroblast growth factor 21 independently of endogenous insulin levels: a novel mechanism of glucagon-stimulated lipolysis?
Authors
Keywords
Adipocytes, Animal study, Endocrine pancreas, Glucose homeostasis, Hepatocytes, Human study, Secretion, Type 1 diabetes
Journal
DIABETOLOGIA
Volume 56, Issue 3, Pages 588-597
Publisher
Springer Nature
Online
2012-12-21
DOI
10.1007/s00125-012-2803-y
References
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Note: Only part of the references are listed.- Fibroblast Growth Factor 21 (FGF-21) and Its Relation to Obesity, Metabolic Syndrome, and Nonalcoholic Fatty Liver in Children: A Longitudinal Analysis
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- Orexin A stimulates glucose uptake, lipid accumulation and adiponectin secretion from 3T3-L1 adipocytes and isolated primary rat adipocytes
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- Paradoxical Regulation of Human FGF21 by Both Fasting and Feeding Signals: Is FGF21 a Nutritional Adaptation Factor?
- (2011) Takashi Uebanso et al. PLoS One
- Physiological modulation of circulating FGF21: relevance of free fatty acids and insulin
- (2010) Knut Mai et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Glucagon and lipid interactions in the regulation of hepatic AMPK signaling and expression of PPARα and FGF21 transcripts in vivo
- (2010) Eric D. Berglund et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Hypocaloric high-protein diet improves fatty liver and hypertriglyceridemia in sucrose-fed obese rats via two pathways
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- Free Fatty Acids Link Metabolism and Regulation of the Insulin-Sensitizing Fibroblast Growth Factor-21
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- Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity
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- Fibroblast Growth Factor 21 Regulates Lipolysis in White Adipose Tissue But Is Not Required for Ketogenesis and Triglyceride Clearance in Liver
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- FGF21 induces PGC-1 and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
- (2009) M. J. Potthoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Glucagon Receptor Is Required for the Adaptive Metabolic Response to Fasting
- (2008) Christine Longuet et al. Cell Metabolism
- Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans
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- FGF21 attenuates lipolysis in human adipocytes - A possible link to improved insulin sensitivity
- (2008) Peter Arner et al. FEBS LETTERS
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