Effects of multiple ascending doses of the glucagon receptor antagonist PF-06291874 in patients with type 2 diabetes mellitus

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Short-term administration of the glucagon receptor antagonist LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes

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Glucagon receptor antagonism induces increased cholesterol absorption

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First proof of pharmacology in humans of a novel glucagon receptor antisense drug

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The design and synthesis of a potent glucagon receptor antagonist with favorable physicochemical and pharmacokinetic properties as a candidate for the treatment of type 2 diabetes mellitus

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Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

(2013) Russell A. Miller et al.   NATURE

Targeted metabolomics for discrimination of systemic inflammatory disorders in critically ill patients

(2012) Diana Schmerler et al.   JOURNAL OF LIPID RESEARCH

Anti-Diabetic Efficacy and Impact on Amino Acid Metabolism of GRA1, a Novel Small-Molecule Glucagon Receptor Antagonist

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Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes

(2011) Jianxin Yang et al.   BMC GENOMICS

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(2011) D. D'Alessio   DIABETES OBESITY & METABOLISM

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The Hill equation: a review of its capabilities in pharmacological modelling

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