A novel HIF-1α/VMP1-autophagic pathway induces resistance to photodynamic therapy in colon cancer cells

Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling

(2016) Hyowon Choi et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Cycling hypoxia: A key feature of the tumor microenvironment

(2016) Carine Michiels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

The potential of photodynamic therapy (PDT)—Experimental investigations and clinical use

(2016) Anna Oniszczuk et al.   BIOMEDICINE & PHARMACOTHERAPY

The ever-expanding role of HIF in tumour and stromal biology

(2016) Edward L. LaGory et al.   NATURE CELL BIOLOGY

Colorectal Adenomas

(2016) Williamson B. Strum   NEW ENGLAND JOURNAL OF MEDICINE

Aloe-emodin-mediated photodynamic therapy induces autophagy and apoptosis in human osteosarcoma cell line MG-63 through the ROS/JNK signaling pathway

(2016) PINGHUA TU et al.   ONCOLOGY REPORTS

Multisciplinary management of patients with liver metastasis from colorectal cancer

(2016) Kathleen De Greef et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

The BH3-mimetic obatoclax reduces HIF-1α levels and HIF-1 transcriptional activity and sensitizes hypoxic colon adenocarcinoma cells to 5-fluorouracil

(2015) Marzia B. Gariboldi et al.   CANCER LETTERS

HIF-1 at the crossroads of hypoxia, inflammation, and cancer

(2015) Kuppusamy Balamurugan   INTERNATIONAL JOURNAL OF CANCER

The Selective Degradation of Synaptic Connexin 43 Protein by Hypoxia-induced Autophagy Impairs Natural Killer Cell-mediated Tumor Cell Killing

(2015) Andrés Tittarelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p53 family and the hypoxia-inducible factors (HIFs): determinants of cancer progression

(2015) Ivano Amelio et al.   TRENDS IN BIOCHEMICAL SCIENCES

The role of autophagy induced by tumor microenvironment in different cells and stages of cancer

(2015) Xue Yang et al.   Cell and Bioscience

A novel mammalian trans-membrane protein reveals an alternative initiation pathway for autophagy

(2014) Maria I. Vaccaro et al.   Autophagy

Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells

(2014) Ming-Feng Wei et al.   Autophagy

Inactivation of von Hippel-Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR-210/VMP1 signaling pathway

(2014) TING LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Hypoxia-induced autophagy reduces radiosensitivity by the HIF-1α/miR-210/Bcl-2 pathway in colon cancer cells

(2014) YONG SUN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

CoCl2, a Mimic of Hypoxia, Induces Formation of Polyploid Giant Cells with Stem Characteristics in Colon Cancer

(2014) Laura M. Lopez-Sánchez et al.   PLoS One

VMP1 is a new player in the regulation of the autophagy-specific phosphatidylinositol 3-kinase complex activation

(2013) Maria I. Molejon et al.   Autophagy

Effects of Nitric Oxide and Reactive Oxygen Species on HIF-1a Stabilization FollowingClostridium DifficileToxin Exposure of the Caco-2 Epithelial Cell Line

(2013) Joshua Y. Lee et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cisplatin-Induced Apoptosis Inhibits Autophagy, Which Acts as a Pro-Survival Mechanism in Human Melanoma Cells

(2013) Barbara Del Bello et al.   PLoS One

NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1α stabilization by inhibiting prolyl hydroxylases activity

(2013) Ying-Na Li et al.   TOXICOLOGY LETTERS

The VMP1-Beclin 1 interaction regulates autophagy induction

(2013) Maria I. Molejon et al.   Scientific Reports

Tumour Hypoxia Affects the Responsiveness of Cancer Cells to Chemotherapy and Promotes Cancer Progression

(2012) Jean-Philippe Cosse et al.   Anti-Cancer Agents in Medicinal Chemistry

Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy

(2012) Paola Maycotte et al.   Autophagy

Novel AKT1-GLI3-VMP1 Pathway Mediates KRAS Oncogene-induced Autophagy in Cancer Cells

(2012) Andrea E. Lo Ré et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

(2011) Tracey R. O’Donovan et al.   Autophagy

Measurements of Tumor Cell Autophagy Predict Invasiveness, Resistance to Chemotherapy, and Survival in Melanoma

(2011) X.-H. Ma et al.   CLINICAL CANCER RESEARCH

Mechanisms of Resistance to Photodynamic Therapy

(2011) A. Casas et al.   CURRENT MEDICINAL CHEMISTRY

Zymophagy, a Novel Selective Autophagy Pathway Mediated by VMP1-USP9x-p62, Prevents Pancreatic Cell Death

(2010) Daniel Grasso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells

(2010) L. Harhaji-Trajkovic et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage

(2010) Michael Dewaele et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Gemcitabine Induces the VMP1 -Mediated Autophagy Pathway to Promote Apoptotic Death in Human Pancreatic Cancer Cells

(2010) Romina Pardo et al.   PANCREATOLOGY

Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity

(2009) S. Wilkinson et al.   GENES & DEVELOPMENT

Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells

(2009) Donglei Liu et al.   MEDICAL ONCOLOGY

Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells

(2008) Seung-Nam Jung et al.   CARCINOGENESIS