Novel AKT1-GLI3-VMP1 Pathway Mediates KRAS Oncogene-induced Autophagy in Cancer Cells

A novel mammalian trans-membrane protein reveals an alternative initiation pathway for autophagy

(2014) Maria I. Vaccaro et al.   Autophagy

Gli Proteins in Development and Disease

(2011) Chi-chung Hui et al.   Annual Review of Cell and Developmental Biology

Involvement of mitophagy in oncogenic K-Ras-induced transformation

(2011) June-Hyung Kim et al.   Autophagy

Autophagy as a mediator of chemotherapy-induced cell death in cancer

(2011) Annick Notte et al.   BIOCHEMICAL PHARMACOLOGY

The multiple roles of autophagy in cancer

(2011) M. T. Rosenfeldt et al.   CARCINOGENESIS

Ras, autophagy and glycolysis

(2011) Rebecca Lock et al.   CELL CYCLE

Pancreatic cancers require autophagy for tumor growth

(2011) S. Yang et al.   GENES & DEVELOPMENT

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

GLI2 Transcription Factor Mediates Cytokine Cross-talk in the Tumor Microenvironment

(2011) Sherine F. Elsawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of Autophagy in Oncogenic K-Ras-induced Malignant Cell Transformation

(2011) Min-Jung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy in Ras-Induced Malignant Transformation: Fatal or Vital?

(2011) Guillermo Mariño et al.   MOLECULAR CELL

C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms

(2010) Ye Tian et al.   CELL

Role of autophagy in suppression of inflammation and cancer

(2010) Eileen White et al.   CURRENT OPINION IN CELL BIOLOGY

Zymophagy, a Novel Selective Autophagy Pathway Mediated by VMP1-USP9x-p62, Prevents Pancreatic Cell Death

(2010) Daniel Grasso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

(2010) Rebecca Lock et al.   MOLECULAR BIOLOGY OF THE CELL

Gemcitabine Induces the VMP1 -Mediated Autophagy Pathway to Promote Apoptotic Death in Human Pancreatic Cancer Cells

(2010) Romina Pardo et al.   PANCREATOLOGY

Context-dependent Regulation of the GLI Code in Cancer by HEDGEHOG and Non-HEDGEHOG Signals

(2010) B. Stecca et al.   Journal of Molecular Cell Biology

Autophagy and tumorigenesis

(2009) Nan Chen et al.   FEBS LETTERS

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation

(2009) O. Nolan-Stevaux et al.   GENES & DEVELOPMENT

Autophagy: Basic Principles and Relevance to Disease

(2008) Mondira Kundu et al.   Annual Review of Pathology-Mechanisms of Disease

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos

(2008) Wenchu Lin et al.   DEVELOPMENTAL DYNAMICS

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE

Autophagy and VMP1 Expression Are Early Cellular Events in Experimental Diabetes

(2008) Daniel Grasso et al.   PANCREATOLOGY