Physiological roles of macrophages

Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis

(2016) Spencer A. Freeman et al.   CELL

Phagocytosis: The Legacy of Metchnikoff

(2016) Siamon Gordon   CELL

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

Autophagy in leukocytes and other cells: mechanisms, subsystem organization, selectivity, and links to innate immunity

(2016) Vojo Deretic   JOURNAL OF LEUKOCYTE BIOLOGY

The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis

(2016) Ido Amit et al.   NATURE IMMUNOLOGY

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

(2016) Peng Yuan et al.   NEURON

Macrophage-epithelial interactions in pulmonary alveoli

(2016) Jahar Bhattacharya et al.   Seminars in Immunopathology

Sepsis: pathophysiology and clinical management

(2016) Jeffrey E Gotts et al.   BMJ-British Medical Journal

Sepsis: pathophysiology and clinical management

(2016) Jeffrey E Gotts et al.   BMJ-British Medical Journal

Brown Fat and Browning for the Treatment of Obesity and Related Metabolic Disorders

(2016) So Hun Kim et al.   Diabetes & Metabolism Journal

Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration

(2015) Amitava Das et al.   AMERICAN JOURNAL OF PATHOLOGY

Non-neuronopathic lysosomal storage disorders: Disease spectrum and treatments

(2015) Gregory M. Pastores et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist

(2015) Aaron M. Cypess et al.   Cell Metabolism

Phagoptosis - Cell Death By Phagocytosis - Plays Central Roles in Physiology, Host Defense and Pathology

(2015) G. Brown et al.   CURRENT MOLECULAR MEDICINE

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair

(2015) Johanna A. Knipper et al.   IMMUNITY

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Interleukin-13 Receptor-α1 Chain Is Essential for Induction of the Alternative Macrophage Activation Pathway by IL-13 but Not IL-4

(2015) Faruk Sheikh et al.   Journal of Innate Immunity

Phagocytosis of apoptotic cells in homeostasis

(2015) Sanja Arandjelovic et al.   NATURE IMMUNOLOGY

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

The resolution of inflammation: Principles and challenges

(2015) Sarah E. Headland et al.   SEMINARS IN IMMUNOLOGY

Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques

(2015) Carlo Condello et al.   Nature Communications

Deficient autophagy unravels the ROS paradox in chronic granulomatous disease

(2014) Frank L van de Veerdonk et al.   Autophagy

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

Origin and Functions of Tissue Macrophages

(2014) Slava Epelman et al.   IMMUNITY

Origin, development, and homeostasis of tissue-resident macrophages

(2014) Malay Haldar et al.   IMMUNOLOGICAL REVIEWS

Of macrophages and red blood cells; a complex love story

(2014) Djuna Z. de Back et al.   Frontiers in Physiology

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

(2013) F. O. Martinez et al.   BLOOD

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

Macrophages: Supportive cells for tissue repair and regeneration

(2013) Bénédicte Chazaud   IMMUNOBIOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Eosinophils secrete IL-4 to facilitate liver regeneration

(2013) Y. P. S. Goh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beyond Stem Cells: Self-Renewal of Differentiated Macrophages

(2013) M. H. Sieweke et al.   SCIENCE

Macrophages and Systemic Iron Homeostasis

(2012) Tomas Ganz   Journal of Innate Immunity

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Intercellular Cross-Talk Among Bone Cells: New Factors and Pathways

(2012) Natalie A. Sims et al.   Current Osteoporosis Reports

Regulatory macrophages: Setting the Threshold for Therapy

(2011) Bryan D. Fleming et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

(2011) Khoa D. Nguyen et al.   NATURE

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Patterns of Pathogenesis: Discrimination of Pathogenic and Nonpathogenic Microbes by the Innate Immune System

(2009) Russell E. Vance et al.   Cell Host & Microbe

The scavenger receptor CD36 plays a role in cytokine-induced macrophage fusion

(2009) L. Helming et al.   JOURNAL OF CELL SCIENCE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Erythroblastic islands: niches for erythropoiesis

(2008) J. A. Chasis et al.   BLOOD

Molecular mechanisms of phagocytic uptake in mammalian cells

(2008) E. Groves et al.   CELLULAR AND MOLECULAR LIFE SCIENCES