Parasite excretory-secretory products and their effects on metabolic syndrome
Published 2017 View Full Article
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Title
Parasite excretory-secretory products and their effects on metabolic syndrome
Authors
Keywords
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Journal
PARASITE IMMUNOLOGY
Volume 39, Issue 5, Pages e12410
Publisher
Wiley
Online
2017-01-09
DOI
10.1111/pim.12410
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Note: Only part of the references are listed.- The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages
- (2017) Raquel Alvarado et al. FASEB JOURNAL
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- (2016) Timothy E. O’Sullivan et al. IMMUNITY
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- (2016) Prakash Babu Narasimhan et al. INFECTION AND IMMUNITY
- The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation
- (2016) Umul Kulthum Ahmed et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Filarial Infection or Antigen Administration Improves Glucose Tolerance in Diet-Induced Obese Mice
- (2016) Afiat Berbudi et al. Journal of Innate Immunity
- The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma
- (2016) J. C. Coltherd et al. Scientific Reports
- Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice
- (2016) Shih-Yin Tsai et al. Cell Reports
- Unraveling the Hygiene Hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications
- (2015) Mathilde Versini et al. BMC Medicine
- Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation
- (2015) Lamyaa Al-Riyami et al. EXPERIMENTAL PARASITOLOGY
- Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice
- (2015) Leonie Hussaarts et al. FASEB JOURNAL
- A parasitic helminth-derived peptide that targets the macrophage lysosome is a novel therapeutic option for autoimmune disease
- (2015) Raquel Alvarado et al. IMMUNOBIOLOGY
- NLRP3 at the interface of metabolism and inflammation
- (2015) Moritz Haneklaus et al. IMMUNOLOGICAL REVIEWS
- The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model
- (2015) Tamar R. Aprahamian et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome
- (2015) Justyna Rzepecka et al. JOURNAL OF AUTOIMMUNITY
- Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity
- (2015) Elise Dalmas et al. NATURE MEDICINE
- PKC/ROS-Mediated NLRP3 Inflammasome Activation Is Attenuated by Leishmania Zinc-Metalloprotease during Infection
- (2015) Marina Tiemi Shio et al. PLoS Neglected Tropical Diseases
- The Parasitic Worm Product ES-62 Targets Myeloid Differentiation Factor 88-Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/lprMice
- (2015) David T. Rodgers et al. Arthritis & Rheumatology
- Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages
- (2014) Mario Kratz et al. Cell Metabolism
- T Cell–Derived IL-22 Amplifies IL-1β–Driven Inflammation in Human Adipose Tissue: Relevance to Obesity and Type 2 Diabetes
- (2014) Elise Dalmas et al. DIABETES
- Macrophage mTORC1 disruption reduces inflammation and insulin resistance in obese mice
- (2014) Hongfeng Jiang et al. DIABETOLOGIA
- ES-62, a therapeutic anti-inflammatory agent evolved by the filarial nematode Acanthocheilonema viteae
- (2014) Miguel A. Pineda et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- Secretory products of helminth parasites as immunomodulators
- (2014) William Harnett MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity
- (2014) Jonathan R. Brestoff et al. NATURE
- Secreted Proteins from the Helminth Fasciola hepatica Inhibit the Initiation of Autoreactive T Cell Responses and Prevent Diabetes in the NOD Mouse
- (2014) Maria E. Lund et al. PLoS One
- Impact of Leishmania mexicana Infection on Dendritic Cell Signaling and Functions
- (2014) Irazú Contreras et al. PLoS Neglected Tropical Diseases
- Adipose Natural Regulatory B Cells Negatively Control Adipose Tissue Inflammation
- (2013) Satoshi Nishimura et al. Cell Metabolism
- Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis
- (2013) Ine M. J. Wolfs et al. FASEB JOURNAL
- Parasitic Nematode-Induced Modulation of Body Weight and Associated Metabolic Dysfunction in Mouse Models of Obesity
- (2013) Zhonghan Yang et al. INFECTION AND IMMUNITY
- The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype
- (2013) Justyna Rzepecka et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Innate sensors of pathogen and stress: Linking inflammation to obesity
- (2013) Chengcheng Jin et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages
- (2013) Ari B. Molofsky et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis
- (2013) J. I. Odegaard et al. SCIENCE
- Arthritis: its prevalence, risk factors, and association with cardiovascular diseases in the United States, 1999 to 2008
- (2012) Kwok Leung Ong et al. ANNALS OF EPIDEMIOLOGY
- The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17-producing cellular network at multiple sites
- (2012) Miguel A. Pineda et al. ARTHRITIS AND RHEUMATISM
- Tumor Necrosis Factor-α Signaling in Macrophages
- (2012) Narayanan Parameswaran et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes
- (2012) Hye-Mi Lee et al. DIABETES
- Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways
- (2012) Prerna Bhargava et al. NATURE MEDICINE
- Helminth infection in populations undergoing epidemiological transition: a friend or foe?
- (2012) Aprilianto Eddy Wiria et al. Seminars in Immunopathology
- Impact of Leishmania metalloprotease GP63 on macrophage signaling
- (2012) Amandine Isnard et al. Frontiers in Cellular and Infection Microbiology
- Inflammatory Mechanisms in Obesity
- (2011) Margaret F. Gregor et al. Annual Review of Immunology
- Akt, FoxO and regulation of apoptosis
- (2011) Xinbo Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Leishmania Repression of Host Translation through mTOR Cleavage Is Required for Parasite Survival and Infection
- (2011) Maritza Jaramillo et al. Cell Host & Microbe
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- (2011) Kirk D.C. Jensen et al. Cell Host & Microbe
- Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression
- (2011) Muhannad Shweash et al. MOLECULAR IMMUNOLOGY
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
- (2011) Daniel A Winer et al. NATURE MEDICINE
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- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
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- (2011) Alessandro S. Farias et al. PLoS One
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- (2011) D. Wu et al. SCIENCE
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- (2011) Barbara A. Butcher et al. PLoS Pathogens
- Decreased Prevalence of Lymphatic Filariasis Among Subjects with Type-1 Diabetes
- (2010) Vivekanandhan Aravindhan et al. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
- The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity
- (2010) Rinke Stienstra et al. Cell Metabolism
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- (2010) Kiichi Nakahira et al. NATURE IMMUNOLOGY
- T-Cell Recruitment and Th1 Polarization in Adipose Tissue During Diet-Induced Obesity in C57BL/6 Mice
- (2010) Katherine J. Strissel et al. Obesity
- The NLRP3 Inflammasome: A Sensor for Metabolic Danger?
- (2010) K. Schroder et al. SCIENCE
- Excretory-secretory products (ESP) from Fasciola hepatica induce tolerogenic properties in myeloid dendritic cells
- (2010) Cristian Falcón et al. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
- Linking calorie restriction to longevity through sirtuins and autophagy: any role for TOR
- (2010) M V Blagosklonny Cell Death & Disease
- Effects of Schistosoma mansoni worms and eggs on circulating cholesterol and liver lipids in mice
- (2009) Ronald G. Stanley et al. ATHEROSCLEROSIS
- MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity
- (2009) André Kleinridders et al. Cell Metabolism
- Modulation of host immune responses by helminth glycans
- (2009) Donald A. Harn et al. IMMUNOLOGICAL REVIEWS
- Major Secretory Antigens of the Helminth Fasciola hepatica Activate a Suppressive Dendritic Cell Phenotype That Attenuates Th17 Cells but Fails To Activate Th2 Immune Responses
- (2009) D. J. Dowling et al. INFECTION AND IMMUNITY
- Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity
- (2009) James P. Hewitson et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
- (2009) Satoshi Nishimura et al. NATURE MEDICINE
- Normalization of obesity-associated insulin resistance through immunotherapy
- (2009) Shawn Winer et al. NATURE MEDICINE
- Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages
- (2008) Sheila Donnelly et al. FASEB JOURNAL
- Akt-dependent regulation of NF- B is controlled by mTOR and Raptor in association with IKK
- (2008) H. C. Dan et al. GENES & DEVELOPMENT
- Soluble egg antigen from Schistosoma japonicum modulates the progression of chronic progressive experimental autoimmune encephalomyelitis via Th2-shift response
- (2008) Xueping Zheng et al. JOURNAL OF NEUROIMMUNOLOGY
- Intracellular Signaling by Akt: Bound to Be Specific
- (2008) T. F. Franke Science Signaling
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