Helminth infection in populations undergoing epidemiological transition: a friend or foe?

Statins Induce Regulatory T Cell Recruitment via a CCL1 Dependent Pathway

(2014) E. Mira et al.   JOURNAL OF IMMUNOLOGY

IL-23 Is Required for the Development of Severe Egg-Induced Immunopathology in Schistosomiasis and for Lesional Expression of IL-17

(2014) L. I. Rutitzky et al.   JOURNAL OF IMMUNOLOGY

Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis

(2014) Alyria Teixeira Dias et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Simvastatin inhibits the pro-inflammatory and pro-thrombotic effects of IL-17 and TNF-α on endothelial cells

(2012) Arnaud Hot et al.   ANNALS OF THE RHEUMATIC DISEASES

Combination of IL-17 and TNFα induces a pro-inflammatory, pro-coagulant and pro-thrombotic phenotype in human endothelial cells

(2012) Arnaud Hot et al.   ANNALS OF THE RHEUMATIC DISEASES

Overexpression of Peroxiredoxin 4 Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice

(2012) Xin Guo et al.   ANTIOXIDANTS & REDOX SIGNALING

Susceptibility and immunity to helminth parasites

(2012) Rick M Maizels et al.   CURRENT OPINION IN IMMUNOLOGY

A helminth cathelicidin-like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPase

(2012) Mark W. Robinson et al.   FASEB JOURNAL

Schistosomiasis

(2012) Bruno Gryseels   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

The Effect of Anthelmintic Treatment During Pregnancy on HIV Plasma Viral Load

(2012) Emily L. Webb et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization

(2012) Helton C. Santiago et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

(2012) Bart Everts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T-Helper 17 Cells Are Associated With Pathology in Human Schistosomiasis

(2012) Moustapha Mbow et al.   JOURNAL OF INFECTIOUS DISEASES

Associations between atopic markers in asthma and intestinal helminth infections in Cuban schoolchildren

(2012) Kim Vereecken et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Schistosomes Induce Regulatory Features in Human and Mouse CD1dhi B Cells: Inhibition of Allergic Inflammation by IL-10 and Regulatory T Cells

(2012) Luciën E. P. M. van der Vlugt et al.   PLoS One

Prevalence of Childhood Atopic Dermatitis: An Urban and Rural Community-Based Study in Shanghai, China

(2012) Feng Xu et al.   PLoS One

New Paradigms in Type 2 Immunity

(2012) B. Pulendran et al.   SCIENCE

Paradoxical associations between soil-transmitted helminths and Plasmodium falciparum infection

(2012) Julián A. Fernández-Niño et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Helminthic therapy: improving mucosal barrier function

(2012) Martin J. Wolff et al.   TRENDS IN PARASITOLOGY

Troubles never come alone

(2012) Alison Elliott et al.   Current Opinion in HIV and AIDS

Epidemiology and immunology of helminth–HIV interactions

(2012) Emily L. Webb et al.   Current Opinion in HIV and AIDS

Regulatory T Cells in Human Lymphatic Filariasis: Stronger Functional Activity in Microfilaremics

(2012) Linda J. Wammes et al.   PLoS Neglected Tropical Diseases

Systematic Review and Meta-Analysis of Methotrexate Use and Risk of Cardiovascular Disease

(2011) Renata Micha et al.   AMERICAN JOURNAL OF CARDIOLOGY

Epidemiology of Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of Malaria Coinfection, Anemia, and Albendazole Treatment Failure

(2011) Debbie Humphries et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Interleukin-10 Released by CD4 + CD25 + Natural Regulatory T Cells Improves Microvascular Endothelial Function Through Inhibition of NADPH Oxidase Activity in Hypertensive Mice

(2011) Modar Kassan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impact of early life exposures to geohelminth infections on the development of vaccine immunity, allergic sensitization, and allergic inflammatory diseases in children living in tropical Ecuador: the ECUAVIDA birth cohort study

(2011) Philip J Cooper et al.   BMC INFECTIOUS DISEASES

A longitudinal study of allergy and intestinal helminth infections in semi urban and rural areas of Flores, Indonesia (ImmunoSPIN Study)

(2011) Firdaus Hamid et al.   BMC INFECTIOUS DISEASES

Peroxiredoxin 2 Deficiency Exacerbates Atherosclerosis in Apolipoprotein E–Deficient Mice

(2011) Jong-Gil Park et al.   CIRCULATION RESEARCH

Parasitic worm therapy for allergy: Is this incongruous or avant-garde medicine?

(2011) D. I. Pritchard et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Evidence for a modulatory effect of IL-10 on both Th1 and Th2 cytokine production: The role of the environment

(2011) Camila A. Figueiredo et al.   CLINICAL IMMUNOLOGY

Filariasis in Africa—treatment challenges and prospects

(2011) A. Hoerauf et al.   CLINICAL MICROBIOLOGY AND INFECTION

Macrophage activation governs schistosomiasis-induced inflammation and fibrosis

(2011) Luke Barron et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Exacerbated egg-induced immunopathology in murine Schistosoma mansoni infection is primarily mediated by IL-17 and restrained by IFN-γ

(2011) Laura I. Rutitzky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Helminth Infection Does Not Reduce Risk for Chronic Inflammatory Disease in a Population-Based Cohort Study

(2011) Peter Bager et al.   GASTROENTEROLOGY

Regulatory B-cell induction by helminths: Implications for allergic disease

(2011) Leonie Hussaarts et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Muc5ac: a critical component mediating the rejection of enteric nematodes

(2011) Sumaira Z. Hasnain et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Filarial Infection Suppresses Malaria-Specific Multifunctional Th1 and Th17 Responses in Malaria and Filarial Coinfections

(2011) S. Metenou et al.   JOURNAL OF IMMUNOLOGY

Heligmosomoides polygyrus Elicits a Dominant Nonprotective Antibody Response Directed against Restricted Glycan and Peptide Epitopes

(2011) J. P. Hewitson et al.   JOURNAL OF IMMUNOLOGY

The impact of parasite infections on the course of multiple sclerosis

(2011) Jorge Correale et al.   JOURNAL OF NEUROIMMUNOLOGY

Neuroschistosomiasis

(2011) Allen G. Ross et al.   JOURNAL OF NEUROLOGY

Interactions between worms and malaria: Good worms or bad worms?

(2011) Mathieu Nacher   MALARIA JOURNAL

Probiotic helminth administration in relapsing–remitting multiple sclerosis: a phase 1 study

(2011) JO Fleming et al.   Multiple Sclerosis Journal

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Integrating Neglected Tropical Diseases into AIDS, Tuberculosis, and Malaria Control

(2011) Peter J. Hotez et al.   NEW ENGLAND JOURNAL OF MEDICINE

Species-specific treatment effects of helminth/HIV-1 co-infection: a systematic review and meta-analysis

(2011) LAURA R. SANGARÉ et al.   PARASITOLOGY

Immunological footprint: the development of a child's immune system in environments rich in microorganisms and parasites

(2011) YENNY DJUARDI et al.   PARASITOLOGY

Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results

(2011) Harriet Mpairwe et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study

(2011) Lena Innala et al.   ARTHRITIS RESEARCH & THERAPY

Mapping the Risk of Anaemia in Preschool-Age Children: The Contribution of Malnutrition, Malaria, and Helminth Infections in West Africa

(2011) Ricardo J. Soares Magalhães et al.   PLOS MEDICINE

Effects of Chronic Ascariasis and Trichuriasis on Cytokine Production and Gene Expression in Human Blood: A Cross-Sectional Study

(2011) Miguel Reina Ortiz et al.   PLoS Neglected Tropical Diseases

CD4+CD25+ Regulatory Cells Contribute to the Regulation of Colonic Th2 Granulomatous Pathology Caused by Schistosome Infection

(2011) Joseph D. Turner et al.   PLoS Neglected Tropical Diseases

A Helminth Immunomodulator Exploits Host Signaling Events to Regulate Cytokine Production in Macrophages

(2011) Christian Klotz et al.   PLoS Pathogens

Inhibition and Role of let-7d in Idiopathic Pulmonary Fibrosis

(2010) Kusum V. Pandit et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Tuberculin Skin-Test Reactions Are Unaffected by the Severity of Hyperendemic Intestinal Helminth Infections and Co-Infections

(2010) Karine Zevallos et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Decreased Prevalence of Lymphatic Filariasis Among Subjects with Type-1 Diabetes

(2010) Vivekanandhan Aravindhan et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Multiple Functions of Peroxiredoxins: Peroxidases, Sensors and Regulators of the Intracellular Messenger H2O2, and Protein Chaperones

(2010) Sue Goo Rhee et al.   ANTIOXIDANTS & REDOX SIGNALING

Impact of repeated four-monthly anthelmintic treatment on Plasmodiuminfection in preschool children: a double-blind placebo-controlled randomized trial

(2010) Patrick Kirwan et al.   BMC INFECTIOUS DISEASES

Experimental hookworm infection: a randomized placebo-controlled trial in asthma

(2010) J. R. Feary et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Long-term periodic anthelmintic treatments are associated with increased allergen skin reactivity

(2010) P. Endara et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Helminths and dendritic cells: Sensing and regulating via pattern recognition receptors, Th2 and Treg responses

(2010) Bart Everts et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T cells in human geohelminth infection suppress immune responses to BCG andPlasmodium falciparum

(2010) Linda J. Wammes et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

In Vitro-Derived Alternatively Activated Macrophages Reduce Colonic Inflammation in Mice

(2010) Meaghan M. Hunter et al.   GASTROENTEROLOGY

Regulation of divalent metal transporter 1 (DMT1) non-IRE isoform by the microRNA Let-7d in erythroid cells

(2010) I. Andolfo et al.   HAEMATOLOGICA

Inflammation, Immunity, and Hypertension

(2010) David G. Harrison et al.   HYPERTENSION

Chronic Intestinal Helminth Infections Are Associated with Immune Hyporesponsiveness and Induction of a Regulatory Network

(2010) C. A. Figueiredo et al.   INFECTION AND IMMUNITY

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

(2010) John R. Grainger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

At Homeostasis Filarial Infections Have Expanded Adaptive T Regulatory but Not Classical Th2 Cells

(2010) S. Metenou et al.   JOURNAL OF IMMUNOLOGY

Lymphatic filariasis and onchocerciasis

(2010) Mark J Taylor et al.   LANCET

Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial

(2010) Emily L Webb et al.   LANCET

Th2 immune response against Schistosoma mansoni infection

(2010) Gabriele Schramm et al.   MICROBES AND INFECTION

Peroxiredoxin: a central player in immune modulation

(2010) M. W. ROBINSON et al.   PARASITE IMMUNOLOGY

Low levels of transforming growth factor-beta (TGF-beta) and reduced suppression of Th2-mediated inflammation in hyperreactive human onchocerciasis

(2010) S. KORTEN et al.   PARASITOLOGY

Plasmodium vivax: Induction of CD4+CD25+FoxP3+ Regulatory T Cells during Infection Are Directly Associated with Level of Circulating Parasites

(2010) Lilian Lacerda Bueno et al.   PLoS One

Concurrent Helminthic Infection Protects Schoolchildren with Plasmodium vivax from Anemia

(2010) Gisely Cardoso Melo et al.   PLoS One

IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity

(2010) R. R. Ricardo-Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-22+ CD4+ T Cells Are Associated with Therapeutic Trichuris trichiura Infection in an Ulcerative Colitis Patient

(2010) M. J. Broadhurst et al.   Science Translational Medicine

Risk factors for atopic and non-atopic asthma in a rural area of Ecuador

(2010) A. L. Moncayo et al.   THORAX

Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis

(2010) Nancy D. Marin et al.   TUBERCULOSIS

Decreased Prevalence of Lymphatic Filariasis among Diabetic Subjects Associated with a Diminished Pro-Inflammatory Cytokine Response (CURES 83)

(2010) Vivekanandhan Aravindhan et al.   PLoS Neglected Tropical Diseases

Helminth Coinfection Does Not Affect Therapeutic Effect of a DNA Vaccine in Mice Harboring Tuberculosis

(2010) Fabiani G. Frantz et al.   PLoS Neglected Tropical Diseases

International variations in associations of allergic markers and diseases in children: ISAAC Phase Two

(2009) G. Weinmayr et al.   ALLERGY

IgE cross-reactivity betweenAscarisand domestic mite allergens: the role of tropomyosin and the nematode polyprotein ABA-1

(2009) N. Acevedo et al.   ALLERGY

Effects of Schistosoma mansoni worms and eggs on circulating cholesterol and liver lipids in mice

(2009) Ronald G. Stanley et al.   ATHEROSCLEROSIS

Prevalence and Progression of Subclinical Atherosclerosis in Younger Adults With Low Short-Term but High Lifetime Estimated Risk For Cardiovascular Disease

(2009) Jarett D. Berry et al.   CIRCULATION

Modulation of malaria-induced immunopathology by concurrent gastrointestinal nematode infection in mice

(2009) M. Segura et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Diabetes in Asia

(2009) Juliana C. N. Chan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Trichuris suis ova therapy for allergic rhinitis: A randomized, double-blind, placebo-controlled clinical trial

(2009) Peter Bager et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Patent Filarial Infection Modulates Malaria-Specific Type 1 Cytokine Responses in an IL-10-Dependent Manner in a Filaria/Malaria-Coinfected Population

(2009) S. Metenou et al.   JOURNAL OF IMMUNOLOGY

Helminth Antigens Modulate Immune Responses in Cells from Multiple Sclerosis Patients through TLR2-Dependent Mechanisms

(2009) J. Correale et al.   JOURNAL OF IMMUNOLOGY

Gastrointestinal Nematode Infection Exacerbates Malaria-Induced Liver Pathology

(2009) H. Helmby   JOURNAL OF IMMUNOLOGY

Human Type 1 and 17 Responses in Latent Tuberculosis Are Modulated by Coincident Filarial Infection through Cytotoxic T Lymphocyte Antigen–4 and Programmed Death–1

(2009) Subash Babu et al.   JOURNAL OF INFECTIOUS DISEASES

Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity

(2009) James P. Hewitson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4

(2009) F Broere et al.   Mucosal Immunology

Filarial Lymphedema Is Characterized by Antigen-Specific Th1 and Th17 Proinflammatory Responses and a Lack of Regulatory T Cells

(2009) Subash Babu et al.   PLoS Neglected Tropical Diseases

Plasmodium falciparum–Mediated Induction of Human CD25hiFoxp3hi CD4 T Cells Is Independent of Direct TCR Stimulation and Requires IL-2, IL-10 and TGFβ

(2009) Anja Scholzen et al.   PLoS Pathogens

Helminth infections associated with multiple sclerosis induce regulatory B cells

(2008) Jorge Correale et al.   ANNALS OF NEUROLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Cardiovascular Disease and Risk Factors in Asia

(2008) Hirotsugu Ueshima et al.   CIRCULATION

Peroxiredoxin1 Prevents Excessive Endothelial Activation and Early Atherosclerosis

(2008) Janka Kisucka et al.   CIRCULATION RESEARCH

Infection with the roundworm Toxocara canis leads to exacerbation of experimental allergic airway inflammation

(2008) E. Pinelli et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages

(2008) Sheila Donnelly et al.   FASEB JOURNAL

Review series on helminths, immune modulation and the hygiene hypothesis: How might infection modulate the onset of type 1 diabetes?

(2008) Anne Cooke   IMMUNOLOGY

Helminths and the IBD hygiene hypothesis

(2008) Joel V. Weinstock et al.   INFLAMMATORY BOWEL DISEASES

IL-12– and IL-23–modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition

(2008) Mark A. Kroenke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ascaris lumbricoides–Induced Interleukin‐10 Is Not Associated with Atopy in Schoolchildren in a Rural Area of the Tropics

(2008) Philip J. Cooper et al.   JOURNAL OF INFECTIOUS DISEASES

Intensity of Intestinal Infection with Multiple Worm Species Is Related to Regulatory Cytokine Output and Immune Hyporesponsiveness

(2008) Joseph D. Turner et al.   JOURNAL OF INFECTIOUS DISEASES

Peroxiredoxin-1 from Schistosoma japonicum functions as a scavenger against hydrogen peroxide but not nitric oxide

(2008) Takashi Kumagai et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

(2008) Ingunn M Stromnes et al.   NATURE MEDICINE

Total IgE in urban Black South African teenagers: The influence of atopy and helminth infection

(2008) M. E. Levin et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Poor immunogenicity of BCG in helminth infected population is associated with increased in vitro TGF-β production

(2008) Daniel Elias et al.   VACCINE