Heptafluoroisopropyl diazomethane (i-C3F7CHN2): in situ generation and synthesis of pyrazoles

Synthesis of N -Nitroso CHF2 -Pyrazolines and Their Transformation into CHF2 -Isoxazolines and -Pyrazoles

(2017) Pavlo S. Lebed et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Halogen-Bond-Promoted Photoactivation of Perfluoroalkyl Iodides: A Photochemical Protocol for Perfluoroalkylation Reactions

(2017) Yaxin Wang et al.   ORGANIC LETTERS

Synthesis of Functionalized 4-Fluoropyridazines

(2017) Alexandra Feraldi-Xypolia et al.   Asian Journal of Organic Chemistry

Iodinated (Perfluoro)alkyl Quinoxalines by Atom Transfer Radical Addition Using ortho -Diisocyanoarenes as Radical Acceptors

(2016) Dirk Leifert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct heptafluoroisopropylation of arylboronic acids via hexafluoropropene (HFP)

(2016) Yajun Li et al.   CHEMICAL COMMUNICATIONS

Rhodium catalyzed synthesis of difluoromethyl cyclopropanes

(2016) Katharina J. Hock et al.   CHEMICAL COMMUNICATIONS

Fluoroalkyl-Substituted Diazomethanes and Their Application in a General Synthesis of Pyrazoles and Pyrazolines

(2016) Lucas Mertens et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of CF2H-Substituted Pyrazolines by [3+2] Cycloaddition between CF2HCHN2and Electron-Deficient Alkenes

(2016) Jue Li et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Fluoroalkyl Pyrazoles from In-Situ-Generated C2F5CHN2and Electron-Deficient Alkenes

(2016) Pavel K. Mykhailiuk et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Copper-mediated aerobic iodination and perfluoroalkylation of boronic acids with (CF 3 ) 2 CFI at room temperature

(2016) Xi-Hai Liu et al.   JOURNAL OF FLUORINE CHEMISTRY

Fluorinated diazoalkanes – a versatile class of reagents for the synthesis of fluorinated compounds

(2016) Lucas Mertens et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Unexpected Reactivity of Trifluoromethyl Diazomethane (CF3CHN2): Electrophilicity of the Terminal N-Atom

(2016) Anton V. Arkhipov et al.   ORGANIC LETTERS

Generation and Synthetic Application of Trifluoromethyl Diazomethane Utilizing Continuous Flow Technologies

(2016) Bartholomäus Pieber et al.   ORGANIC LETTERS

In Situ Generation of Difluoromethyl Diazomethane for [3+2] Cycloadditions with Alkynes

(2015) Pavel K. Mykhailiuk   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver(I)-CatalyzedN-Trifluoroethylation of Anilines andO-Trifluoroethylation of Amides with 2,2,2-Trifluorodiazoethane

(2015) Haiqing Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Three-component synthesis of C2F5-substituted pyrazoles from C2F5CH2NH2·HCl, NaNO2and electron-deficient alkynes

(2015) Pavel K Mykhailiuk   Beilstein Journal of Organic Chemistry

Dialkylzinc-Mediated Cross-Coupling Reactions of Perfluoroalkyl and Perfluoroaryl Halides with Aryl Halides

(2015) Hisano Kato et al.   CHEMISTRY-A EUROPEAN JOURNAL

New Life for Diazoacetonitrile (N2CHCN): in situ Generation and Practical Synthesis of CN-Pyrazoles

(2015) Pavel K. Mykhailiuk   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Selective Incorporation of Fluorine in Pyrazoles

(2015) Joseph C. Sloop et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

[3 + 2] Cycloaddition of arynes with CF 3 CHN 2 : Access to 3-trifluoromethyl-1 H -indazoles

(2015) Long Sun et al.   JOURNAL OF FLUORINE CHEMISTRY

Three-component synthesis of fluorinated pyrazoles from fluoroalkylamines, NaNO2 and electron-deficient alkynes

(2015) Pavel K. Mykhailiuk   ORGANIC & BIOMOLECULAR CHEMISTRY

Diastereoselective Synthesis of Vicinally Bis(trifluoromethylated) Alkylboron Compounds through Successive Insertions of 2,2,2-Trifluorodiazoethane

(2014) Gary A. Molander et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Generation of C2F5CHN2In Situ and Its First Reaction: [3+2] Cycloaddition with Alkenes

(2014) Pavel K. Mykhailiuk    CHEMISTRY-A EUROPEAN JOURNAL

Rapid Trifluoromethylation and Perfluoroalkylation of Five-Membered Heterocycles by Photoredox Catalysis in Continuous Flow

(2014) Natan J. W. Straathof et al.   ChemSusChem

Switchable 2,2,2-Trifluoroethylation andgem-Difluorovinylation of Organoboronic Acids with 2,2,2-Trifluorodiazoethane

(2014) Guojiao Wu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Multigram Synthesis of Fluoroalkyl-Substituted Pyrazole-4-carboxylic Acids

(2014) Rustam T. Iminov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[n.1.0]alkanes: Advanced Building Blocks for Drug Discovery

(2014) Olexiy S. Artamonov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A General, Regiospecific Synthetic Route to Perfluoroalkylated Arenes via Arenediazonium Salts with RFCu(CH3CN) Complexes

(2014) Dong-Fang Jiang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

One-Pot Synthesis of CF3-Substituted Pyrazolines/Pyrazoles from Electron-Deficient Alkenes/Alkynes and CF3CHN2Generated in situ: Optimized Synthesis of Tris(trifluoromethyl)pyrazole

(2014) Evgeniy Y. Slobodyanyuk et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of CF3-Containing 3,3′-Cyclopropyl Spirooxindoles by Sequential [3 + 2] Cycloaddition/Ring Contraction of Ylideneoxindoles with 2,2,2-Trifluorodiazoethane

(2014) Tian-Ren Li et al.   JOURNAL OF ORGANIC CHEMISTRY

A Direct Copper-Promoted Three-Component Entry to Trifluoromethylketoximes

(2014) Shuai Wang et al.   ORGANIC LETTERS

Regioselective Cycloaddition of Trifluorodiazoethane with Electron-Deficient Allenic Esters and Ketones: Access to CF3-Substituted Pyrazolines and Pyrazoles

(2014) Fa-Guang Zhang et al.   ORGANIC LETTERS

Silver-Mediated Cycloaddition of Alkynes with CF3CHN2: Highly Regioselective Synthesis of 3-Trifluoromethylpyrazoles

(2013) Feng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cupration of C2F5H: Isolation, Structure, and Synthetic Applications of [K(DMF)2][(t-BuO)Cu(C2F5)]. Highly Efficient Pentafluoroethylation of Unactivated Aryl Bromides

(2013) Anton Lishchynskyi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Brønsted acid-catalyzed diastereo- and enantioselective synthesis of CF3-substituted aziridines

(2012) Zhuo Chai et al.   CHEMICAL COMMUNICATIONS

Synthesis of diversely fluorinated pyrazoles as novel active agrochemical ingredients

(2012) Florence Giornal et al.   JOURNAL OF FLUORINE CHEMISTRY

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

(2011) Santos Fustero et al.   CHEMICAL REVIEWS

Polyfluoroalkylation of 2-aminothiazoles

(2011) Qingqing Qi et al.   JOURNAL OF FLUORINE CHEMISTRY

“Reported, but Still Unknown.” A Closer Look into 3,4-Bis- and 3,4,5-Tris(trifluoromethyl)pyrazoles

(2011) Igor I. Gerus et al.   JOURNAL OF ORGANIC CHEMISTRY

Iron-Catalyzed Cyclopropanation with Trifluoroethylamine Hydrochloride and Olefins in Aqueous Media: In Situ Generation of Trifluoromethyl Diazomethane

(2009) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Trifluoromethyl‐Substituted Proline Analogues as19F NMR Labels for Peptides in the Polyproline II Conformation

(2008) Pavel K. Mykhailiuk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

(2008) Kenneth L. Kirk   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Atropisomerism about a heptafluoroisopropyl to aryl bond in 5-amino-4-heptafluoroisopropyl indazole

(2008) Bahiya Atouioual et al.   TETRAHEDRON LETTERS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS