Three-component synthesis of fluorinated pyrazoles from fluoroalkylamines, NaNO2 and electron-deficient alkynes

Three-component synthesis of C2F5-substituted pyrazoles from C2F5CH2NH2·HCl, NaNO2and electron-deficient alkynes

(2015) Pavel K Mykhailiuk   Beilstein Journal of Organic Chemistry

Nucleophilic tetrafluoroethylation of carbonyl compounds with fluorinated sulfones

(2015) Jiří Václavík et al.   JOURNAL OF FLUORINE CHEMISTRY

Synthesis of tetrafluoroethyl- and tetrafluoroethylene-containing amines by the reaction of silanes with enamines under acidic conditions

(2015) Yana Chernykh et al.   JOURNAL OF FLUORINE CHEMISTRY

Diastereoselective Synthesis of Vicinally Bis(trifluoromethylated) Alkylboron Compounds through Successive Insertions of 2,2,2-Trifluorodiazoethane

(2014) Gary A. Molander et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Good Partnership between Sulfur and Fluorine: Sulfur-Based Fluorination and Fluoroalkylation Reagents for Organic Synthesis

(2014) Chuanfa Ni et al.   CHEMICAL REVIEWS

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Generation of C2F5CHN2In Situ and Its First Reaction: [3+2] Cycloaddition with Alkenes

(2014) Pavel K. Mykhailiuk    CHEMISTRY-A EUROPEAN JOURNAL

Recent Advances in Trifluoromethylation Reactions with Electrophilic Trifluoromethylating Reagents

(2014) Sebastián Barata-Vallejo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Switchable 2,2,2-Trifluoroethylation andgem-Difluorovinylation of Organoboronic Acids with 2,2,2-Trifluorodiazoethane

(2014) Guojiao Wu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Multigram Synthesis of Fluoroalkyl-Substituted Pyrazole-4-carboxylic Acids

(2014) Rustam T. Iminov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[n.1.0]alkanes: Advanced Building Blocks for Drug Discovery

(2014) Olexiy S. Artamonov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Design and Synthesis of 3-Trifluoromethyl-3H-pyrazoles and Further Investigations of Their Transformation to 1H-Pyrazoles

(2014) Qiang Sha et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

One-Pot Synthesis of CF3-Substituted Pyrazolines/Pyrazoles from Electron-Deficient Alkenes/Alkynes and CF3CHN2Generated in situ: Optimized Synthesis of Tris(trifluoromethyl)pyrazole

(2014) Evgeniy Y. Slobodyanyuk et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Successful fluorine-containing herbicide agrochemicals

(2014) Tomoya Fujiwara et al.   JOURNAL OF FLUORINE CHEMISTRY

Synthesis of CF3-Containing 3,3′-Cyclopropyl Spirooxindoles by Sequential [3 + 2] Cycloaddition/Ring Contraction of Ylideneoxindoles with 2,2,2-Trifluorodiazoethane

(2014) Tian-Ren Li et al.   JOURNAL OF ORGANIC CHEMISTRY

A Direct Copper-Promoted Three-Component Entry to Trifluoromethylketoximes

(2014) Shuai Wang et al.   ORGANIC LETTERS

Regioselective Cycloaddition of Trifluorodiazoethane with Electron-Deficient Allenic Esters and Ketones: Access to CF3-Substituted Pyrazolines and Pyrazoles

(2014) Fa-Guang Zhang et al.   ORGANIC LETTERS

A New Synthesis and Process Development of Bis(fluoroalkyl)pyrazoles As Novel Agrophores

(2014) Florence Giornal et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Synthesis of Fluorinated and Nonfluorinated Tebufenpyrad Analogues for the Study of Anti-angiogenesis MOA

(2014) Raquel Román et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Synthesis and Applications of α-Trifluoromethylated Alkylboron Compounds

(2013) O. Andreea Argintaru et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver-Mediated Cycloaddition of Alkynes with CF3CHN2: Highly Regioselective Synthesis of 3-Trifluoromethylpyrazoles

(2013) Feng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

A New Life for an Old Reagent: Fluoroalkyl Amino Reagents as Efficient Tools for the Synthesis of Diversely Fluorinated Pyrazoles

(2013) Sergiy Pazenok et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of trans-2-(Trifluoromethyl)cyclopropanes via Suzuki Reactions with an N-Methyliminodiacetic Acid Boronate

(2013) Matthew A. J. Duncton et al.   ORGANIC LETTERS

Synthesis of Trifluoromethylated Isoxazolidines: 1,3-Dipolar Cycloaddition of Nitrosoarenes, (Trifluoromethyl)diazomethane, and Alkenes

(2013) Gary A. Molander et al.   ORGANIC LETTERS

Chiral Brønsted acid-catalyzed diastereo- and enantioselective synthesis of CF3-substituted aziridines

(2012) Zhuo Chai et al.   CHEMICAL COMMUNICATIONS

The New Age of Electrophilic Perfluoro­alk­ylation Reactions

(2012) Yohan Macé et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Efficient synthesis of 5′-fluoroalkoxythiazoles via α-bromo-α-fluoroalkoxyacetophenones Hantzsch type cyclization with thioureas or thioamides

(2012) Taras M. Sokolenko et al.   JOURNAL OF FLUORINE CHEMISTRY

Synthesis of diversely fluorinated pyrazoles as novel active agrochemical ingredients

(2012) Florence Giornal et al.   JOURNAL OF FLUORINE CHEMISTRY

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

(2011) Santos Fustero et al.   CHEMICAL REVIEWS

Development of PhSCF2CF2SiMe3 as a Tandem Anion and Radical Tetrafluoroethylene Equivalent: Preparation of Tetrafluoroethyl-Substituted Alcohols and Tetrafluorotetrahydropyrans

(2011) Yana Chernykh et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

“Reported, but Still Unknown.” A Closer Look into 3,4-Bis- and 3,4,5-Tris(trifluoromethyl)pyrazoles

(2011) Igor I. Gerus et al.   JOURNAL OF ORGANIC CHEMISTRY

Trifluoromethylation of aryl and heteroaryl halides

(2011) Sudipta Roy et al.   TETRAHEDRON

Enantioselective Cobalt-Catalyzed Preparation of Trifluoromethyl-Substituted Cyclopropanes

(2010) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Cyclopropenation of Alkynes: Synthesis of Trifluoromethyl-Substituted Cyclopropenes

(2010) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

Fluorine in health care: Organofluorine containing blockbuster drugs

(2010) David O’Hagan   JOURNAL OF FLUORINE CHEMISTRY

Iron-Catalyzed Cyclopropanation with Trifluoroethylamine Hydrochloride and Olefins in Aqueous Media: In Situ Generation of Trifluoromethyl Diazomethane

(2009) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in the Synthesis of Pyrazoles. A Review

(2009) Santos Fustero et al.   ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL

Dibutyl 2-(trifluoromethyl)cyclopropylboronate as a useful (trifluoromethyl)cyclopropyl donor: application to antagonists of TRPV1

(2009) Matthew A.J. Duncton et al.   TETRAHEDRON LETTERS

Synthesis of Trifluoromethyl‐Substituted Proline Analogues as19F NMR Labels for Peptides in the Polyproline II Conformation

(2008) Pavel K. Mykhailiuk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS