Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells

Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches

(2017) C C Wong et al.   ONCOGENE

Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism

(2017) Tao Shan et al.   ONCOLOGY REPORTS

Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet

(2016) Stephen L. Slocum et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Effects of G6PD activity inhibition on the viability, ROS generation and mechanical properties of cervical cancer cells

(2016) Zishui Fang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis

(2016) Sandra Fernandes Martins et al.   BMC CANCER

Colonic Lamina Propria Inflammatory Cells from Patients with IBD Induce the Nuclear Factor-E2 Related Factor-2 Thereby Leading to Greater Proteasome Activity and Apoptosis Protection in Human Colonocytes

(2016) Marie-Luise Kruse et al.   INFLAMMATORY BOWEL DISEASES

Bioenergetics and redox adaptations of astrocytes to neuronal activity

(2016) Juan P. Bolaños   JOURNAL OF NEUROCHEMISTRY

Energy metabolism in the acquisition and maintenance of stemness

(2016) Clifford D.L. Folmes et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming

(2016) Kate E. Hawkins et al.   Cell Reports

Oncometabolic Nuclear Reprogramming of Cancer Stemness

(2016) Javier A. Menendez et al.   Stem Cell Reports

Dysregulation of the Keap1–Nrf2 pathway in cancer: Figure 1

(2015) Hanna M. Leinonen et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Keap1/Nrf2 pathway in the frontiers of cancer and non-cancer cell metabolism

(2015) Dionysios V. Chartoumpekis et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Metabolic reprogramming: the emerging concept and associated therapeutic strategies

(2015) Go J. Yoshida   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth

(2015) Emily D. Montal et al.   MOLECULAR CELL

Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth

(2015) Emma E. Vincent et al.   MOLECULAR CELL

Epithelial–mesenchymal transition in human cancer: Comprehensive reprogramming of metabolism, epigenetics, and differentiation

(2015) Linna Li et al.   PHARMACOLOGY & THERAPEUTICS

Warburg Effect or Reverse Warburg Effect? A Review of Cancer Metabolism

(2015) Xiao Dong Xu et al.   Oncology Research and Treatment

Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression

(2014) Patrizia Sanità et al.   BMC CANCER

Neuronal Progenitor Maintenance Requires Lactate Metabolism and PEPCK-M-Directed Cataplerosis

(2014) Zaida Álvarez et al.   CEREBRAL CORTEX

PCK2 activation mediates an adaptive response to glucose depletion in lung cancer

(2014) K Leithner et al.   ONCOGENE

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Oncogenic functions of the transcription factor Nrf2

(2013) Irene Gañán-Gómez et al.   FREE RADICAL BIOLOGY AND MEDICINE

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

The SLC16 gene family – Structure, role and regulation in health and disease

(2013) Andrew P. Halestrap   MOLECULAR ASPECTS OF MEDICINE

Metabolic targets for cancer therapy

(2013) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Toward clinical application of the Keap1–Nrf2 pathway

(2013) Takafumi Suzuki et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay

(2012) T. Fiaschi et al.   CANCER RESEARCH

Using the “reverse Warburg effect” to identify high-risk breast cancer patients

(2012) Agnieszka K. Witkiewicz et al.   CELL CYCLE

Emerging avenues linking inflammation and cancer

(2012) Joydeb Kumar Kundu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of monocarboxylate transporters in human cancers: state of the art

(2012) Céline Pinheiro et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Metabolic symbiosis in cancer: Refocusing the Warburg lens

(2012) Erica C. Nakajima et al.   MOLECULAR CARCINOGENESIS

TGF-β1-dependent L1CAM expression has an essential role in macrophage-induced apoptosis resistance and cell migration of human intestinal epithelial cells

(2012) H Schäfer et al.   ONCOGENE

The Warburg effect: Insights from the past decade

(2012) Mohita Upadhyay et al.   PHARMACOLOGY & THERAPEUTICS

Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers

(2011) Agnieszka K. Witkiewicz et al.   CELL CYCLE

Evidence for a stromal-epithelial “lactate shuttle” in human tumors

(2011) Diana Whitaker-Menezes et al.   CELL CYCLE

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

Stromal–epithelial metabolic coupling in cancer: Integrating autophagy and metabolism in the tumor microenvironment

(2011) Ubaldo E. Martinez-Outschoorn et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Inflammatory Macrophages Induce Nrf2 Transcription Factor-dependent Proteasome Activity in Colonic NCM460 Cells and Thereby Confer Anti-apoptotic Protection

(2011) Susanne Sebens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prognostic significance of monocarboxylate transporter 4 expression in patients with colorectal cancer

(2011) YOSHIFUMI NAKAYAMA et al.   Experimental and Therapeutic Medicine

Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway

(2010) John D. Hayes et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)

(2009) A Arlt et al.   ONCOGENE

Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells

(2009) Olivier Feron   RADIOTHERAPY AND ONCOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

(2008) T. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas

(2008) Céline Pinheiro et al.   VIRCHOWS ARCHIV