USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation

The FANC pathway and mitosis: A replication legacy

(2011) Valeria Naim et al.   CELL CYCLE

SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype

(2011) Chantal Stoepker et al.   NATURE GENETICS

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

(2011) Gerry P Crossan et al.   NATURE GENETICS

Mutations of the SLX4 gene in Fanconi anemia

(2011) Yonghwan Kim et al.   NATURE GENETICS

New partners for Chk1

(2010) George Iliakis   CELL CYCLE

Expanded roles of the Fanconi anemia pathway in preserving genomic stability

(2010) Y. Kee et al.   GENES & DEVELOPMENT

Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway

(2010) Ihn Young Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spontaneous abrogation of the G2 DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients

(2010) Raphael Ceccaldi et al.   JOURNAL OF CLINICAL INVESTIGATION

DNA Repair Has a New FAN1 Club

(2010) Lara O'Donnell et al.   MOLECULAR CELL

Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia

(2010) Adele Adamo et al.   MOLECULAR CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Fanconi anemia and breast cancer susceptibility meet again

(2010) Ephrat Levy-Lahad   NATURE GENETICS

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2

(2010) Eloïse Dray et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

(2010) P. Pace et al.   SCIENCE

Constitutive Activation of the DNA Damage Signaling Pathway in Acute Myeloid Leukemia with Complex Karyotype: Potential Importance for Checkpoint Targeting Therapy

(2009) C. Cavelier et al.   CANCER RESEARCH

DDB1 Targets Chk1 to the Cul4 E3 Ligase Complex in Normal Cycling Cells and in Cells Experiencing Replication Stress

(2009) V. Leung-Pineda et al.   CANCER RESEARCH

Inactivation of Murine Usp1 Results in Genomic Instability and a Fanconi Anemia Phenotype

(2009) Jung Min Kim et al.   DEVELOPMENTAL CELL

Human DNA damage response and repair deficiency syndromes: Linking genomic instability and cell cycle checkpoint proficiency

(2009) Claudia Kerzendorfer et al.   DNA REPAIR

Functional Interaction between the Fanconi Anemia D2 Protein and Proliferating Cell Nuclear Antigen (PCNA) via a Conserved Putative PCNA Interaction Motif

(2009) Niall G. Howlett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

USP7 counteracts SCFβTrCP- but not APCCdh1-mediated proteolysis of Claspin

(2009) Helene Faustrup et al.   JOURNAL OF CELL BIOLOGY

Checkpoint Signaling from a Single DNA Interstrand Crosslink

(2009) Merav Ben-Yehoyada et al.   MOLECULAR CELL

The F Box Protein Fbx6 Regulates Chk1 Stability and Cellular Sensitivity to Replication Stress

(2009) You-Wei Zhang et al.   MOLECULAR CELL

The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities

(2009) Valeria Naim et al.   NATURE CELL BIOLOGY

Chk1 and Claspin potentiate PCNA ubiquitination

(2008) X. H. Yang et al.   GENES & DEVELOPMENT

FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex

(2008) Spencer J. Collis et al.   MOLECULAR CELL

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

G2/M checkpoint stringency is a key parameter in the sensitivity of AML cells to genotoxic stress

(2008) C Didier et al.   ONCOGENE