HERC2-USP20 axis regulates DNA damage checkpoint through Claspin

Ubiquitin-specific Peptidase 20 Regulates Rad17 Stability, Checkpoint Kinase 1 Phosphorylation and DNA Repair by Homologous Recombination

(2014) Ilanchezhian Shanmugam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deubiquitylating Enzymes and DNA Damage Response Pathways

(2013) Xavier Jacq et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

Causes and consequences of replication stress

(2013) Michelle K. Zeman et al.   NATURE CELL BIOLOGY

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA damage–inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

(2012) Jannie Rendtlew Danielsen et al.   JOURNAL OF CELL BIOLOGY

The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

(2011) Simon Bekker-Jensen et al.   FEBS LETTERS

MDC1 collaborates with TopBP1 in DNA replication checkpoint control

(2011) Jiadong Wang et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin-Specific Peptidase 20 Targets TRAF6 and Human T Cell Leukemia Virus Type 1 Tax To Negatively Regulate NF- B Signaling

(2011) J. Yasunaga et al.   JOURNAL OF VIROLOGY

ATR Autophosphorylation as a Molecular Switch for Checkpoint Activation

(2011) Shizhou Liu et al.   MOLECULAR CELL

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

HERC2 Is an E3 Ligase That Targets BRCA1 for Degradation

(2010) W. Wu et al.   CANCER RESEARCH

Rad17 Plays a Central Role in Establishment of the Interaction between TopBP1 and the Rad9-Hus1-Rad1 Complex at Stalled Replication Forks

(2010) Joon Lee et al.   MOLECULAR BIOLOGY OF THE CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein

(2010) T.-H. Kang et al.   NUCLEIC ACIDS RESEARCH

ATR: a master conductor of cellular responses to DNA replication stress

(2010) Rachel Litman Flynn et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dissecting the role of ubiquitylation in the DNA damage response checkpoint in G2

(2009) F Bassermann et al.   CELL DEATH AND DIFFERENTIATION

The deubiquitinases USP33 and USP20 coordinate β2 adrenergic receptor recycling and resensitization

(2009) Magali Berthouze et al.   EMBO JOURNAL

The ubiquitin landscape at DNA double-strand breaks

(2009) Troy E. Messick et al.   JOURNAL OF CELL BIOLOGY

The Unstructured C-Terminal Tail of the 9-1-1 Clamp Subunit Ddc1 Activates Mec1/ATR via Two Distinct Mechanisms

(2009) Vasundhara M. Navadgi-Patil et al.   MOLECULAR CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

(2009) Simon Bekker-Jensen et al.   NATURE CELL BIOLOGY

Assembly of checkpoint and repair machineries at DNA damage sites

(2009) Michael S.Y. Huen et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Cdc14B-Cdh1-Plk1 Axis Controls the G2 DNA-Damage-Response Checkpoint

(2008) Florian Bassermann et al.   CELL

TopBP1 activates ATR through ATRIP and a PIKK regulatory domain

(2008) D. A. Mordes et al.   GENES & DEVELOPMENT