Endocrine-disrupting chemicals and fatty liver disease

Metabolism disrupting chemicals and metabolic disorders

(2017) Jerrold J. Heindel et al.   REPRODUCTIVE TOXICOLOGY

The Role of Nuclear Receptors in the Pathophysiology, Natural Course, and Drug Treatment of NAFLD in Humans

(2016) Stefano Ballestri et al.   ADVANCES IN THERAPY

Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum

(2016) Timothy Hardy et al.   Annual Review of Pathology-Mechanisms of Disease

Nuclear receptors and nonalcoholic fatty liver disease 1 1This article is part of a Special Issue entitled: Xenobiotic nuclear receptors: New Tricks for An Old Dog, edited by Dr. Wen Xie.

(2016) Matthew C. Cave et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Small-molecule modulators of PXR and CAR

(2016) Sergio C. Chai et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice

(2016) Volodymyr P. Tryndyak et al.   BMC GENOMICS

Hepatocellular Carcinoma in Obesity, Type 2 Diabetes, and NAFLD

(2016) Helen L. Reeves et al.   DIGESTIVE DISEASES AND SCIENCES

Exposure to Famine in Early Life and Nonalcoholic Fatty Liver Disease in Adulthood

(2016) Ningjian Wang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD

(2016) Barbara Gross et al.   Nature Reviews Endocrinology

Developmental origins of NAFLD: a womb with a clue

(2016) Stephanie R. Wesolowski et al.   Nature Reviews Gastroenterology & Hepatology

Overlapping nongenomic and genomic actions of thyroid hormone and steroids

(2015) Stephen R. Hammes et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

The identification of nuclear receptors associated with hepatic steatosis to develop and extend adverse outcome pathways

(2015) Claire L. Mellor et al.   CRITICAL REVIEWS IN TOXICOLOGY

Nonalcoholic Fatty Liver Disease and Type 2 Diabetes: Common Pathophysiologic Mechanisms

(2015) Chiara Saponaro et al.   Current Diabetes Reports

EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

(2015) A. C. Gore et al.   ENDOCRINE REVIEWS

Nonalcoholic fatty liver disease: Update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine

(2015) Mazen Noureddin et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Phosphorylation of the nuclear receptor corepressor 1 by protein kinase B switches its corepressor targets in the liver in mice

(2015) Young Suk Jo et al.   HEPATOLOGY

Nonalcoholic Fatty Liver Disease

(2015) Mary E. Rinella   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Fetal and infant exposure to the Chinese famine increases the risk of fatty liver disease in Chongqing, China

(2015) Jiang-Peng Chen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Minireview: Nuclear Receptor Coregulators of the p160 Family: Insights into Inflammation and Metabolism

(2015) David A. Rollins et al.   MOLECULAR ENDOCRINOLOGY

Endocrine disruptors and obesity

(2015) Jerrold J. Heindel et al.   Nature Reviews Endocrinology

Epidemiology and Natural History of Nonalcoholic Fatty Liver Disease

(2015) Sanjaya Satapathy et al.   SEMINARS IN LIVER DISEASE

Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis

(2015) Banrida Wahlang et al.   TOXICOLOGICAL SCIENCES

Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis

(2015) Rita S. Strakovsky et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease

(2015) Müjdat Zeybel et al.   Clinical Epigenetics

The Amelioration of Hepatic Steatosis by Thyroid Hormone Receptor Agonists Is Insufficient to Restore Insulin Sensitivity in Ob/Ob Mice

(2015) Alexandro J. Martagón et al.   PLoS One

Regulation of the nongenomic actions of retinoid X receptor-α by targeting the coregulator-binding sites

(2014) Xiao-kun Zhang et al.   ACTA PHARMACOLOGICA SINICA

Fatty liver indices in the multiethnic United States National Health and Nutrition Examination Survey

(2014) C. E. Ruhl et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Transcriptional Coregulators: Fine-Tuning Metabolism

(2014) Laurent Mouchiroud et al.   Cell Metabolism

Effects of co-exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polychlorinated biphenyls on nonalcoholic fatty liver disease in mice

(2014) Qiuli Shan et al.   ENVIRONMENTAL TOXICOLOGY

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet

(2014) Jie Wei et al.   JOURNAL OF ENDOCRINOLOGY

High Fat Diet Feeding Exaggerates Perfluorooctanoic Acid-Induced Liver Injury in Mice via Modulating Multiple Metabolic Pathways

(2014) Xiaobing Tan et al.   PLoS One

Identification of Environmental Chemicals Associated with the Development of Toxicant-associated Fatty Liver Disease in Rodents

(2014) Laila Al-Eryani et al.   TOXICOLOGIC PATHOLOGY

Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease

(2014) Banrida Wahlang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chronic exposure of mice to environmental endocrine-disrupting chemicals disturbs their energy metabolism

(2014) Yuanxiang Jin et al.   TOXICOLOGY LETTERS

Steroid receptor coactivators: servants and masters for control of systems metabolism

(2014) Erin Stashi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Agouti mouse: a biosensor for environmental epigenomics studies investigating the developmental origins of health and disease

(2014) Randy L Jirtle   Epigenomics

Epigenetic Mechanisms Underlying the Link between Non-Alcoholic Fatty Liver Diseases and Nutrition

(2014) Joo Lee et al.   Nutrients

Maternal chocolate and sucrose soft drink intake induces hepatic steatosis in rat offspring associated with altered lipid gene expression profile

(2013) M. Kjaergaard et al.   Acta Physiologica

Maternal western diet primes non-alcoholic fatty liver disease in adult mouse offspring

(2013) M. G. M. Pruis et al.   Acta Physiologica

Relationship Between Methylome and Transcriptome in Patients With Nonalcoholic Fatty Liver Disease

(2013) Susan K. Murphy et al.   GASTROENTEROLOGY

Maternal obesity programs offspring nonalcoholic fatty liver disease by innate immune dysfunction in mice

(2013) Angelina Mouralidarane et al.   HEPATOLOGY

Dietary fructose in nonalcoholic fatty liver disease

(2013) Miriam B. Vos et al.   HEPATOLOGY

Ursodeoxycholic Acid Inhibits Liver X Receptor α-mediated Hepatic Lipogenesis via Induction of the Nuclear Corepressor SMILE

(2013) Ji-Min Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vitamin A and retinoid signaling: genomic and nongenomic effects

(2013) Ziad Al Tanoury et al.   JOURNAL OF LIPID RESEARCH

Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice

(2013) Banrida Wahlang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Deacetylase-Independent Function of HDAC3 in Transcription and Metabolism Requires Nuclear Receptor Corepressor

(2013) Zheng Sun et al.   MOLECULAR CELL

Proteomic Analysis of Coregulators Bound to ERα on DNA and Nucleosomes Reveals Coregulator Dynamics

(2013) Charles E. Foulds et al.   MOLECULAR CELL

Research Resource: Tissue- and Pathway-Specific Metabolomic Profiles of the Steroid Receptor Coactivator (SRC) Family

(2013) Brian York et al.   MOLECULAR ENDOCRINOLOGY

The global NAFLD epidemic

(2013) Rohit Loomba et al.   Nature Reviews Gastroenterology & Hepatology

From NAFLD to NASH to cirrhosis—new insights into disease mechanisms

(2013) Alexander Wree et al.   Nature Reviews Gastroenterology & Hepatology

NAFLD, NASH and liver cancer

(2013) Gregory A. Michelotti et al.   Nature Reviews Gastroenterology & Hepatology

Phosphorylation: a fundamental regulator of steroid receptor action

(2013) Lindsey S. Treviño et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Fructose as a key player in the development of fatty liver disease

(2013) Metin Basaranoglu   WORLD JOURNAL OF GASTROENTEROLOGY

Association Between Nonalcoholic Fatty Liver Disease and Risk for Hepatocellular Cancer, Based on Systematic Review

(2012) Donna L. White et al.   Clinical Gastroenterology and Hepatology

A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates

(2012) Melissa A. Suter et al.   FASEB JOURNAL

Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism

(2012) Volodymyr Tryndyak et al.   FASEB JOURNAL

In-depth Proteomic Characterization of Endogenous Nuclear Receptors in Mouse Liver

(2012) Qiongming Liu et al.   MOLECULAR & CELLULAR PROTEOMICS

The estrogenic endocrine disrupting chemical bisphenol A (BPA) and obesity

(2012) Frederick S. vom Saal et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

(2012) Zheng Sun et al.   NATURE MEDICINE

S-adenosylmethionine in Liver Health, Injury, and Cancer

(2012) Shelly C. Lu et al.   PHYSIOLOGICAL REVIEWS

Developmental origins of chronic disease

(2012) D.J.P. Barker   PUBLIC HEALTH

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Endocrine Disruptors: From Endocrine to Metabolic Disruption

(2011) Cristina Casals-Casas et al.   Annual Review of Physiology

The role of methyl-binding proteins in chromatin organization and epigenome maintenance

(2011) A. Fournier et al.   Briefings in Functional Genomics

Thiazolidinediones Enhance Sodium-Coupled Bicarbonate Absorption from Renal Proximal Tubules via PPARγ-Dependent Nongenomic Signaling

(2011) Yoko Endo et al.   Cell Metabolism

Minireview: Recent Advances in Extranuclear Steroid Receptor Actions

(2011) Stephen R. Hammes et al.   ENDOCRINOLOGY

Diagnosis and Evaluation of Nonalcoholic Fatty Liver Disease

(2011) Mikako Obika et al.   Experimental Diabetes Research

Transcription coactivator mediator subunit MED1 Is required for the development of fatty liver in the mouse

(2011) Liang Bai et al.   HEPATOLOGY

Ligand-dependent corepressor acts as a novel corepressor of thyroid hormone receptor and represses hepatic lipogenesis in mice

(2011) Yiyun Song et al.   JOURNAL OF HEPATOLOGY

Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets

(2011) Jiong Li et al.   JOURNAL OF HEPATOLOGY

Genetic determinants of hepatic steatosis in man

(2011) Amanda J. Hooper et al.   JOURNAL OF LIPID RESEARCH

Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver

(2011) Nicole G. Ashino et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Endocrine disruptors in the etiology of type 2 diabetes mellitus

(2011) Paloma Alonso-Magdalena et al.   Nature Reviews Endocrinology

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring

(2010) Bianca M. Gregorio et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The Language of Histone Crosstalk

(2010) Jung-Shin Lee et al.   CELL

A structural view of nuclear hormone receptor: endocrine disruptor interactions

(2010) Albane le Maire et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide

(2010) Marta Varela-Rey et al.   HEPATOLOGY

Maternal obesity during pregnancy and lactation programs the development of offspring non-alcoholic fatty liver disease in mice

(2010) Jude A. Oben et al.   JOURNAL OF HEPATOLOGY

Deletion of steroid receptor coactivator-3 gene ameliorates hepatic steatosis

(2010) Xinran Ma et al.   JOURNAL OF HEPATOLOGY

Coupling global methylation and gene expression profiles reveal key pathophysiological events in liver injury induced by a methyl-deficient diet

(2010) Volodymyr P. Tryndyak et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Jung Sub Lim et al.   Nature Reviews Gastroenterology & Hepatology

Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology

(2010) B. York et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-term maternal high-fat feeding from weaning through pregnancy and lactation predisposes offspring to hypertension, raised plasma lipids and fatty liver in mice

(2009) Maqsood M. Elahi et al.   BRITISH JOURNAL OF NUTRITION

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression

(2009) Kimberley D. Bruce et al.   HEPATOLOGY

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

(2009) Igor P. Pogribny et al.   JOURNAL OF HEPATOLOGY

Endocrine disruptive chemicals: mechanisms of action and involvement in metabolic disorders

(2009) Elin Swedenborg et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease

(2009) B. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide Coactivation Analysis of PGC-1α Identifies BAF60a as a Regulator of Hepatic Lipid Metabolism

(2008) Siming Li et al.   Cell Metabolism

Thyroid hormone (T3) and TRβ agonist GC-1 inhibit/reverse nonalcoholic fatty liver in rats

(2008) Andrea Perra et al.   FASEB JOURNAL

Nuclear receptor cofactor receptor interacting protein 140 controls hepatic triglyceride metabolism during wasting in mice

(2008) Mauricio Berriel Diaz et al.   HEPATOLOGY

Fructose consumption as a risk factor for non-alcoholic fatty liver disease

(2008) Xiaosen Ouyang et al.   JOURNAL OF HEPATOLOGY

Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome

(2008) Kjersti M Aagaard-Tillery et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Effect of folate deficiency on placental DNA methylation in hyperhomocysteinemic rats

(2008) Ji-Myung Kim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Absence of the SRC-2 Coactivator Results in a Glycogenopathy Resembling Von Gierke's Disease

(2008) A. R. Chopra et al.   SCIENCE

Mechanisms of Disease Progression in Nonalcoholic Fatty Liver Disease

(2008) Janice Jou et al.   SEMINARS IN LIVER DISEASE