Regulation of the nongenomic actions of retinoid X receptor-α by targeting the coregulator-binding sites

Chemopreventive Effects of RXR-Selective Rexinoid Bexarotene on Intestinal Neoplasia of ApcMin/+ Mice

(2015) Naveena B. Janakiram et al.   NEOPLASIA

Nuclear Receptors, RXR, and the Big Bang

(2014) Ronald M. Evans et al.   CELL

Sulindac-Derived RXRα Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site

(2014) Liqun Chen et al.   CHEMISTRY & BIOLOGY

Type 1 TNF Receptor Forms a Complex with and Uses Jak2 and c-Src to Selectively Engage Signaling Pathways That Regulate Transcription Factor Activity

(2014) R. Pincheira et al.   JOURNAL OF IMMUNOLOGY

Apoptotic and neurotoxic actions of 4-para-nonylphenol are accompanied by activation of retinoid X receptor and impairment of classical estrogen receptor signaling

(2014) E. Litwa et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Identification of a New RXRα Antagonist Targeting the Coregulator-Binding Site

(2014) Fan Chen et al.   ACS Medicinal Chemistry Letters

Low Dose Bexarotene Treatment Rescues Dopamine Neurons and Restores Behavioral Function in Models of Parkinson’s Disease

(2013) Krista McFarland et al.   ACS Chemical Neuroscience

Regulation of proteolytic cleavage of retinoid X receptor-  by GSK-3 

(2013) W. Gao et al.   CARCINOGENESIS

The Importance of the Retinoid X Receptor Alpha in Modulating Inflammatory Signaling in Acute Murine Colitis

(2013) Rebecca Knackstedt et al.   DIGESTIVE DISEASES AND SCIENCES

The Retinoid X Receptor Agonist Bexarotene Relieves Positive Symptoms of Schizophrenia

(2013) Vladimir Lerner et al.   JOURNAL OF CLINICAL PSYCHIATRY

Retinoid X receptor activation is essential for docosahexaenoic acid protection of retina photoreceptors

(2013) Olga L. German et al.   JOURNAL OF LIPID RESEARCH

Retinoid X receptors in macrophage biology

(2013) Tamás Rőszer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Targeting Truncated Retinoid X Receptor-  by CF31 Induces TNF- -Dependent Apoptosis

(2012) G.-H. Wang et al.   CANCER RESEARCH

Beyond the Ligand-Binding Pocket: Targeting Alternate Sites in Nuclear Receptors

(2012) Laura Caboni et al.   MEDICINAL RESEARCH REVIEWS

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

Modulation of RXR function through ligand design

(2011) Efrén Pérez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The retinoid X receptors and their ligands

(2011) Marcia I. Dawson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis

(2011) Zhaokang Cheng et al.   EUROPEAN HEART JOURNAL

A conserved surface on the ligand binding domain of nuclear receptors for allosteric control

(2011) Víctor Buzón et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

NSAID Sulindac and Its Analog Bind RXRα and Inhibit RXRα-Dependent AKT Signaling

(2010) Hu Zhou et al.   CANCER CELL

Danthron Functions as a Retinoic X Receptor Antagonist by Stabilizing Tetramers of the Receptor

(2010) Haitao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RXRα Ablation in Epidermal Keratinocytes Enhances UVR-Induced DNA Damage, Apoptosis, and Proliferation of Keratinocytes and Melanocytes

(2010) Zhixing Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Retinoid X receptor   controls innate inflammatory responses through the up-regulation of chemokine expression

(2010) V. Nunez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Potential of "Rexinoids" in Cancer Prevention and Treatment

(2009) T. Tanaka et al.   CANCER RESEARCH

Minireview: Not Picking Pockets: Nuclear Receptor Alternate-Site Modulators (NRAMs)

(2009) Terry W. Moore et al.   MOLECULAR ENDOCRINOLOGY

Impaired cervical homeostasis upon selective ablation of RXRα in epithelial cells

(2008) R. Ocadiz-Delgado et al.   GENESIS

Phase III Trial Comparing Carboplatin, Paclitaxel, and Bexarotene With Carboplatin and Paclitaxel in Chemotherapy-Naïve Patients With Advanced or Metastatic Non–Small-Cell Lung Cancer: SPIRIT II

(2008) George R. Blumenschein et al.   JOURNAL OF CLINICAL ONCOLOGY

Randomized Phase III Trial Comparing Bexarotene (L1069-49)/Cisplatin/Vinorelbine With Cisplatin/Vinorelbine in Chemotherapy-Naïve Patients With Advanced or Metastatic Non–Small-Cell Lung Cancer: SPIRIT I

(2008) Rodryg Ramlau et al.   JOURNAL OF CLINICAL ONCOLOGY

During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain

(2008) Jennifer Thompson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting phosphoinositide 3-kinase—Moving towards therapy

(2007) Romina Marone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS