- Home
- Publications
- Publication Search
- Publication Details
Title
Harnessing Solute Carrier Transporters for Precision Oncology
Authors
Keywords
-
Journal
MOLECULES
Volume 22, Issue 4, Pages 539
Publisher
MDPI AG
Online
2017-03-28
DOI
10.3390/molecules22040539
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155
- (2017) Michael D. Nyquist et al. MOLECULAR CANCER RESEARCH
- Loss of SLCO1B3 drives taxane resistance in prostate cancer
- (2016) Ellen S de Morrée et al. BRITISH JOURNAL OF CANCER
- Antibody-drug conjugates—an emerging class of cancer treatment
- (2016) Nikolaos Diamantis et al. BRITISH JOURNAL OF CANCER
- Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer
- (2016) V Coothankandaswamy et al. BRITISH JOURNAL OF PHARMACOLOGY
- Dioxonaphthoimidazoliums are Potent and Selective Rogue Stem Cell Clearing Agents with SOX2-Suppressing Properties
- (2016) Si-Han Sherman Ho et al. ChemMedChem
- Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics
- (2016) B Prasad et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Bipolar Androgen Therapy for Men With Androgen Ablation Naïve Prostate Cancer: Results From the Phase II BATMAN Study
- (2016) Michael T. Schweizer et al. PROSTATE
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Impact of Membrane Drug Transporters on Resistance to Small-Molecule Tyrosine Kinase Inhibitors
- (2016) Claudia Neul et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Effects of YM155 on survivin levels and viability in neuroblastoma cells with acquired drug resistance
- (2016) Yvonne Voges et al. Cell Death & Disease
- Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-κB pathway
- (2016) Si Han Sherman Ho et al. Oncotarget
- Hallmarks of glycosylation in cancer
- (2016) Jennifer Munkley et al. Oncotarget
- Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy
- (2015) Nilay Thakkar et al. AAPS Journal
- Protein Glycosylation in Cancer
- (2015) Sean R. Stowell et al. Annual Review of Pathology-Mechanisms of Disease
- Translating cancer genomes and transcriptomes for precision oncology
- (2015) Sameek Roychowdhury et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Amino Acid Transporters in Cancer and Their Relevance to "Glutamine Addiction": Novel Targets for the Design of a New Class of Anticancer Drugs
- (2015) Y. D. Bhutia et al. CANCER RESEARCH
- A Call for Systematic Research on Solute Carriers
- (2015) Adrián César-Razquin et al. CELL
- Inhibition of Survivin with YM155 Induces Durable Tumor Response in Anaplastic Thyroid Cancer
- (2015) A. Mehta et al. CLINICAL CANCER RESEARCH
- Phase I Study of Vorinostat as a Radiation Sensitizer with 131I-Metaiodobenzylguanidine (131I-MIBG) for Patients with Relapsed or Refractory Neuroblastoma
- (2015) S. G. DuBois et al. CLINICAL CANCER RESEARCH
- Individualized dosing of tyrosine kinase inhibitors: are we there yet?
- (2015) Djoeke de Wit et al. DRUG DISCOVERY TODAY
- Antiproliferative, DNA intercalation and redox cycling activities of dioxonaphtho[2,3-d]imidazolium analogs of YM155: A structure–activity relationship study
- (2015) Si-Han Sherman Ho et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
- (2015) Manuele Rebsamen et al. NATURE
- SLC transporters as therapeutic targets: emerging opportunities
- (2015) Lawrence Lin et al. NATURE REVIEWS DRUG DISCOVERY
- Coexpression of Multiple ABC-Transporters is Strongly Associated with Treatment Response in Childhood Acute Myeloid Leukemia
- (2015) Stephan Bartholomae et al. PEDIATRIC BLOOD & CANCER
- Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: Results from a pilot clinical study
- (2015) M. T. Schweizer et al. Science Translational Medicine
- YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network
- (2015) Eloïse Véquaud et al. Oncotarget
- Transcriptomic and Immunohistochemical Profiling of SLC6A14 in Pancreatic Ductal Adenocarcinoma
- (2015) Alan R. Penheiter et al. Biomed Research International
- Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets
- (2015) Marçal Pastor-Anglada et al. Frontiers in Pharmacology
- Sunitinib-induced severe toxicities in a Japanese patient with the ABCG2 421 AA genotype
- (2015) Yuji Miura et al. BMC CANCER
- Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics
- (2014) Bhagwat Prasad et al. AAPS Journal
- Phase II, multicenter, open-label, randomized study of YM155 plus docetaxel as first-line treatment in patients with HER2-negative metastatic breast cancer
- (2014) Michael R. Clemens et al. BREAST CANCER RESEARCH AND TREATMENT
- YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells
- (2014) S M Cheng et al. BRITISH JOURNAL OF PHARMACOLOGY
- Toxicity of targeted therapy: Implications for response and impact of genetic polymorphisms
- (2014) Sariah Liu et al. CANCER TREATMENT REVIEWS
- Practical Guidelines for Therapeutic Drug Monitoring of Anticancer Tyrosine Kinase Inhibitors: Focus on the Pharmacokinetic Targets
- (2014) Huixin Yu et al. CLINICAL PHARMACOKINETICS
- Review of therapeutic drug monitoring of anticancer drugs part two – Targeted therapies
- (2014) Nicolas Widmer et al. EUROPEAN JOURNAL OF CANCER
- Review of therapeutic drug monitoring of anticancer drugs part 1 – Cytotoxics
- (2014) Angelo Paci et al. EUROPEAN JOURNAL OF CANCER
- Therapeutic drug monitoring in cancer – Are we missing a trick?
- (2014) Christophe Bardin et al. EUROPEAN JOURNAL OF CANCER
- Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway
- (2014) Julia Roediger et al. Molecular Cancer
- Small Molecule Inhibitor YM155-Mediated Activation of Death Receptor 5 Is Crucial for Chemotherapy-Induced Apoptosis in Pancreatic Carcinoma
- (2014) X. Zhao et al. MOLECULAR CANCER THERAPEUTICS
- The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity
- (2014) Georg E Winter et al. Nature Chemical Biology
- What do drug transporters really do?
- (2014) Sanjay K. Nigam NATURE REVIEWS DRUG DISCOVERY
- A phase 2, multicenter, open-label study of sepantronium bromide (YM155) plus docetaxel in patients with stage III (unresectable) or stage IV melanoma
- (2014) Ragini Kudchadkar et al. Cancer Medicine
- The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy
- (2014) Yangzom D. Bhutia et al. Asian Journal of Pharmaceutical Sciences
- Structure and function of nucleotide sugar transporters: Current progress
- (2014) Barbara Hadley et al. Computational and Structural Biotechnology Journal
- A phase I/II study of sepantronium bromide (YM155, survivin suppressor) with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer
- (2013) R. J. Kelly et al. ANNALS OF ONCOLOGY
- Targeting Survivin in Cancer: Novel Drug Development Approaches
- (2013) Bernd Groner et al. BIODRUGS
- Understanding, recognizing, and managing toxicities of targeted anticancer therapies
- (2013) Grace K. Dy et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Influence on the behavior of lung cancer H1299 cells by silencing SLC35F2 expression
- (2013) Xiao Li et al. Cancer Cell International
- Upregulation of Peptide Transporters PEPT1 and PEPT2 by Janus Kinase JAK2
- (2013) Zohreh Hosseinzadeh et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Pancreatic Cancer hENT1 Expression and Survival From Gemcitabine in Patients From the ESPAC-3 Trial
- (2013) William Greenhalf et al. JNCI-Journal of the National Cancer Institute
- The SLC22 family with transporters of organic cations, anions and zwitterions
- (2013) Hermann Koepsell MOLECULAR ASPECTS OF MEDICINE
- Roles of the nucleotide sugar transporters (SLC35 family) in health and disease
- (2013) Zhiwei Song MOLECULAR ASPECTS OF MEDICINE
- The SLCO (former SLC21) superfamily of transporters
- (2013) Bruno Hagenbuch et al. MOLECULAR ASPECTS OF MEDICINE
- The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29
- (2013) James D. Young et al. MOLECULAR ASPECTS OF MEDICINE
- The ABCs of membrane transporters in health and disease (SLC series): Introduction
- (2013) Matthias A. Hediger et al. MOLECULAR ASPECTS OF MEDICINE
- Proton-coupled oligopeptide transporter family SLC15: Physiological, pharmacological and pathological implications
- (2013) David E. Smith et al. MOLECULAR ASPECTS OF MEDICINE
- Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases
- (2013) Lars Petter Jordheim et al. NATURE REVIEWS DRUG DISCOVERY
- Aberrant PSA glycosylation—a sweet predictor of prostate cancer
- (2013) Sarah Gilgunn et al. Nature Reviews Urology
- Control of glutamine metabolism by the tumor suppressor Rb
- (2013) M R Reynolds et al. ONCOGENE
- The SLC38 family of sodium–amino acid co-transporters
- (2013) Stefan Bröer PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Inhibition of pluripotent stem cell-derived teratoma formation by small molecules
- (2013) M.-O. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors
- (2013) Debra H. Josephs et al. THERAPEUTIC DRUG MONITORING
- Sepantronium Bromide (YM155) induces disruption of the ILF3/p54nrb complex, which is required for survivin expression
- (2012) Tomohiro Yamauchi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- ABC transporters and their role in nucleoside and nucleotide drug resistance
- (2012) Yu Fukuda et al. BIOCHEMICAL PHARMACOLOGY
- Targeting survivin in cancer
- (2012) Dario C. Altieri CANCER LETTERS
- SLC1A5 Mediates Glutamine Transport Required for Lung Cancer Cell Growth and Survival
- (2012) M. Hassanein et al. CLINICAL CANCER RESEARCH
- Contribution of tumoral and host solute carriers to clinical drug response
- (2012) Jason A. Sprowl et al. DRUG RESISTANCE UPDATES
- Pharmacogenetic determinants of mercaptopurine disposition in children with acute lymphoblastic leukemia
- (2012) Tiphaine Adam de Beaumais et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Developmental diseases caused by impaired nucleotide sugar transporters
- (2012) Li Liu et al. GLYCOCONJUGATE JOURNAL
- Endocrine and metabolic regulation of renal drug transporters
- (2012) Lindsay L. Yacovino et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Proton pump inhibitors significantly increase the intracellular concentration of nilotinib, but not imatinib in target CML cells
- (2012) D L White et al. LEUKEMIA
- Interleukin Enhancer-binding Factor 3/NF110 Is a Target of YM155, a Suppressant of Survivin
- (2012) Naoto Nakamura et al. MOLECULAR & CELLULAR PROTEOMICS
- The mitochondrial transporter family SLC25: Identification, properties and physiopathology
- (2012) Ferdinando Palmieri MOLECULAR ASPECTS OF MEDICINE
- HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
- (2012) Ainara Elorza et al. MOLECULAR CELL
- Expression Profile and Functional Activity of Peptide Transporters in Prostate Cancer Cells
- (2012) Wanyi Tai et al. MOLECULAR PHARMACEUTICS
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- Radiosynthesis, biodistribution and imaging of [11C]YM155, a novel survivin suppressant, in a human prostate tumor-xenograft mouse model
- (2012) Yoshihiro Murakami et al. NUCLEAR MEDICINE AND BIOLOGY
- Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel
- (2012) Uchenna O. Njiaju et al. Pharmacogenetics and Genomics
- Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy
- (2012) Sabrina Angelini et al. PHARMACOLOGICAL RESEARCH
- Adaptive auto-regulation of androgen receptor provides a paradigm shifting rationale for bipolar androgen therapy (BAT) for castrate resistant human prostate cancer
- (2012) John T. Isaacs et al. PROSTATE
- A phase II study of YM155, a novel small-molecule suppressor of survivin, in castration-resistant taxane-pretreated prostate cancer
- (2011) A. W. Tolcher et al. ANNALS OF ONCOLOGY
- OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies
- (2011) Megan Roth et al. BRITISH JOURNAL OF PHARMACOLOGY
- A phase II study of the survivin suppressant YM155 in patients with refractory diffuse large B-cell lymphoma
- (2011) Bruce D. Cheson et al. CANCER
- Expression of SLCO Transport Genes in Castration-Resistant Prostate Cancer and Impact of Genetic Variation in SLCO1B3 and SLCO2B1 on Prostate Cancer Outcomes
- (2011) J. L. Wright et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Induction of autophagy-dependent apoptosis by the survivin suppressant YM155 in prostate cancer cells
- (2011) Qinwen Wang et al. CANCER LETTERS
- CNT1 Expression Influences Proliferation and Chemosensitivity in Drug-Resistant Pancreatic Cancer Cells
- (2011) Y. D. Bhutia et al. CANCER RESEARCH
- Vorinostat Increases Expression of Functional Norepinephrine Transporter in Neuroblastoma In Vitro and In Vivo Model Systems
- (2011) S. S. More et al. CLINICAL CANCER RESEARCH
- Utility of P-Glycoprotein and Organic Cation Transporter 1 Double-Transfected LLC-PK1 Cells for Studying the Interaction of YM155 Monobromide, Novel Small-Molecule Survivin Suppressant, with P-Glycoprotein
- (2011) M. Iwai et al. DRUG METABOLISM AND DISPOSITION
- Targeted BIRC5 silencing using YM155 causes cell death in neuroblastoma cells with low ABCB1 expression
- (2011) Fieke Lamers et al. EUROPEAN JOURNAL OF CANCER
- SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer
- (2011) Senthil Karunakaran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study
- (2011) Caicun Zhou et al. LANCET ONCOLOGY
- Highly expressed SLC35F2 in non-small cell lung cancer is associated with pathological staging
- (2011) Jun Wang Molecular Medicine Reports
- Expression of OATP Family Members in Hormone-Related Cancers: Potential Markers of Progression
- (2011) Heather Pressler et al. PLoS One
- The prognostic significance of human equilibrative nucleoside transporter 1 expression in patients with metastatic bladder cancer treated with gemcitabine-cisplatin-based combination chemotherapy
- (2010) Nagahide Matsumura et al. BJU INTERNATIONAL
- Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models
- (2010) Takahito Nakahara et al. CANCER SCIENCE
- Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
- (2010) Michael C Haffner et al. NATURE GENETICS
- Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation
- (2010) C. D. Klaassen et al. PHARMACOLOGICAL REVIEWS
- Hijacking Solute Carriers for Proton-Coupled Drug Transport
- (2010) Catriona M. H. Anderson et al. PHYSIOLOGY
- Clinical Relevance of a Pharmacogenetic Approach Using Multiple Candidate Genes to Predict Response and Resistance to Imatinib Therapy in Chronic Myeloid Leukemia
- (2009) D. H. Kim et al. CLINICAL CANCER RESEARCH
- Characterization of Human Organic Cation Transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-Mediated Transport of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small Molecule Survivin Suppressant
- (2009) T. Minematsu et al. DRUG METABOLISM AND DISPOSITION
- Tissue-Specific mRNA Expression Profiles of Human Solute Carrier 35 Transporters
- (2009) Masuhiro Nishimura et al. Drug Metabolism and Pharmacokinetics
- Endoplasmic Reticulum/Golgi Nucleotide Sugar Transporters Contribute to the Cellular Release of UDP-sugar Signaling Molecules
- (2009) Juliana I. Sesma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multicenter Phase II Trial of YM155, a Small-Molecule Suppressor of Survivin, in Patients With Advanced, Refractory, Non–Small-Cell Lung Cancer
- (2009) Giuseppe Giaccone et al. JOURNAL OF CLINICAL ONCOLOGY
- Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy
- (2008) Senthil Karunakaran et al. BIOCHEMICAL JOURNAL
- Pharmacokinetic Considerations for New Targeted Therapies
- (2008) SD Baker et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Phase I and Pharmacokinetic Study of YM155, a Small-Molecule Inhibitor of Survivin
- (2008) Anthony W. Tolcher et al. JOURNAL OF CLINICAL ONCOLOGY
- Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters
- (2008) M. Okabe et al. MOLECULAR CANCER THERAPEUTICS
- Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond
- (2008) Vadivel Ganapathy et al. PHARMACOLOGY & THERAPEUTICS
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
- (2008) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search